Polysorb MP powder for suspension preparation, for oral administration, 50g

Х acute and chronic intoxication of various origins in adults and children;
Х acute intestinal infections of any genesis, including foodborne toxicoinfections, as well as diarrheal syndrome of non-infectious origin, dysbiosis (as part of complex therapy);
Х purulent-septic diseases, accompanied by severe intoxication ;
Х acute poisoning with potent and poisonous substances, including drugs and alcohol, alkaloids, salts of heavy metals, etc .;
Х food and drug allergies ;
Х hyperbilirubinemia (viral hepatitisand other jaundice) and hyperazotemia (chronic renal failure);
Х residents of ecologically unfavorable regions and workers of hazardous industries, for the purpose of prevention .

Inside, only as an aqueous suspension!

To obtain a suspension, the required amount of the drug is thoroughly mixed in 1 / 4Ц1 / 2 glass of water. It is recommended to prepare a fresh suspension before each dose of the drug and drink it 1 hour before meals or other drugs.

The average daily dose for adults is 0.1Ц0.2 g / kg (6Ц12 g).

Frequency rate of admission - 3-4 times a day.

The maximum daily dose in adults is 0.33 g / kg.

The dose for children is calculated depending on body weight (see table).

Table

1 teaspoon with a 'slide' - 1 g of the drug; 1 tablespoon with a 'slide' - 3 g of the drug.

In case of food allergies, the drug should be taken immediately before or during a meal, the daily dose of the drug is divided into 3 doses during the day.

The duration of treatment depends on the diagnosis and the severity of the disease. The course of treatment for acute intoxication is 3-5 days; for allergic diseases and chronic intoxication - up to 10-14 days. Repetition of the course of treatment is possible in 2-3 weeks, on the recommendation of a doctor.

Features of the use of the drug PolysorbЃ MP in various conditions and diseases

Foodborne diseases and acute poisoning

Treatment should be started in the first hours or the first day of illness!

Rinse the stomach with 0.5-1% suspension of PolysorbЃ MP. In case of severe poisoning on the first day, gastric lavage is carried out through a tube every 4-6 hours, along with this, the drug is given orally. A single dose in adults can be 0.1-0.15 g / kg 2-3 times a day.

If necessary, the treatment is extended for another 3-5 days.

Acute intestinal infections

It is recommended to start treatment with PolysorbЃ MP in the first hours or days of the disease in combination with other therapy methods.

On the first day of treatment, the daily dose is given for 5 hours with intervals between doses of 1 hour. The daily dose is 0.2 g / kg.

On the second day of treatment, the daily dose is given in 4 doses, in between meals and other medications. The duration of treatment is 3-5 days.

If there is a clinical effect, you can limit yourself to this course or, if necessary, continue treatment for another 2-3 days.

Viral hepatitis treatment

In the complex therapy of viral hepatitis, PolysorbЃ MP is used as a detoxifying agent in usual doses during the first 7-10 days of illness.

Chronic renal failure

The courses of treatment with PolysorbЃ MP are 25-30 days at a daily dose of 0.15-0.2 g / kg. The courses can be repeated at intervals of 2-3 weeks.

Alcoholism, drug addiction

PolysorbЃ MP is used for the treatment of alcohol withdrawal syndromes, at a dose of 0.2 g / kg / day, for 5-10 days.

Dermatology

The course of treatment for psoriasis and eczema is 14-21 days, and for other dermatoses - 10-14 days.

Allergic diseases

In cases of acute drug and food allergies, the stomach and intestines are preliminarily washed with 0.5Ц1% suspension of PolysorbЃ MP. Then the drug is given in usual doses until the onset of the clinical effect. For chronic food allergies, courses of 7-10-15 days are recommended, the drug is taken immediately before meals.

Similar courses are shown for acute recurrent urticaria and Quincke's edema, eosinophilia on the eve and against the background of exacerbation of pollinosis and other atopy.

The daily dose is 0.2 g / kg until the onset of the clinical effect.

The inclusion of the drug PolysorbЃ MP in complex therapy for acute and recurrent urticaria and angioedema, bronchial asthma, hay fever and, especially, atopic dermatitis is shown.

The duration of the course depends on the persistence of clinical manifestations and is, on average, 5-10 days.

Treatment and prevention of gestosis

The daily dose of PolysorbЃ MP for prophylactic purposes is 0.1 g / kg, and for medicinal purposes - 0.15Ц0.2 g / kg.

The duration of the course of treatment in both cases is 10-14 days. The courses can be repeated after 10-14 days.

Treatment and prevention of diseases associated with the development of atherosclerosis.

It is recommended to use PolysorbЃ MP in patients with diseases caused by the development of atherosclerosis, at a dose of 0.1Ц0.15 g / kg / day for 1Ц1.5 months.

For the prevention of atherosclerosis, especially in persons suffering from hypercholesterol and lipidemia, PolysorbЃ MP is used in the same doses and at the same time. If necessary, courses can be repeated after 1Ц1.5 months.

Active ingredient: colloidal silicon dioxide

Х Peptic ulcer and 12 duodenal ulcer in the acute phase;
Х Bleeding from the gastrointestinal tract;
Х Intestinal atony;
Х Individual intolerance to the drug.

Trade name of the drug : Polysorb MP
International non-proprietary name or grouping name: Colloidal silicon dioxide
Dosage form : powder for preparation of suspension for oral administration

Ingredients : colloidal silicon dioxide

Description : Light white or white with a bluish shade, odorless powder. When shaken with water, forms a suspension.

Pharmacotherapeutic group: enterosorbent agent.

Pharmacological properties . Polysorb MP (medical oral) is an inorganic, non-selective, multifunctional enterosorbent based on highly dispersed silica with a particle size of up to 0.09 mm, with the chemical formula SiO2. The sorption capacity of the drug for internal use is 300 m? / G.

Pharmacodynamics.
Polysorb MP has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including pathogenic bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metal salts, radionuclides , alcohol. Polysorb MP also sorbs some metabolic products of the body, including an excess of bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.

Pharmacokinetics .
Polysorb MP is not degraded or absorbed in the gastrointestinal tract and is excreted unchanged.

Indications for use :
Х acute and chronic intoxication of various origins in adults and children;
Х acute intestinal infections of any genesis, including food toxicoinfections, as well as diarrheal syndrome of non-infectious origin, dysbiosis (as part of complex therapy);
Х purulent-septic diseases, accompanied by severe intoxication ;
Х acute poisoning with potent and poisonous substances, including drugs and alcohol, alkaloids, salts of heavy metals, etc .;
Х food and drug allergies ;
Х hyperbilirubinemia (viral hepatitisand other jaundice) and hyperazotemia (chronic renal failure);
Х residents of ecologically unfavorable regions and workers of hazardous industries, for the purpose of prevention .

Contraindications:

Х Peptic ulcer and 12 duodenal ulcer in the acute phase;
Х Bleeding from the gastrointestinal tract;
Х Intestinal atony;
Х Individual intolerance to the drug.

Dosage and administration
Polysorb MP is taken orally only in the form of an aqueous suspension! To obtain a suspension, the required amount of the drug is thoroughly mixed in 1/4 -1/2 glass of water. It is recommended to prepare a fresh suspension before each dose of the drug and drink it 1 hour before meals or other medications.

The average daily dose in adults is 0.1-0.2 g / kg of body weight (6-12 g). The drug is taken in 3-4 doses during the day. The maximum daily dose in adults is 0.33 g / kg of body weight (20 g). The dose for children is calculated depending on body weight (see table).

1 teaspoon of Polysorb MP 'with top' contains 1 g of the drug

1 dining room 'top' 2.5-3 g.

In cases of food allergy, the drug is taken immediately before a meal, the daily dose of Polysorb MP is divided into three doses during the day. The duration of treatment depends on the diagnosis and severity of the disease, the course of treatment for acute intoxications is 3-5 days; for allergic diseases, chronic intoxications, the duration of treatment is up to 10-14 days. Repeated courses after 2-3 weeks, on the recommendation of a doctor.

Features of the use of Polysorb MP for various diseases.

1. Food poisoning and acute poisoning . It is recommended to start therapy with gastric lavage with 0.5-1% suspension of Polysorb MP. In case of severe poisoning on the first day, gastric lavage is carried out through a probe every 4-6 hours, along with this, the drug is given orally. A single dose in adults can be 0.1-0.15 mg / kg of the patient's body weight 2-3 times a day.

2. Acute intestinal infections . It is recommended to start treatment with Polysorb MP in the first hours or days of the disease in combination with other methods of treatment. On the first day, the daily dose is given within 5 hours at intervals of 1 hour between doses. On the 2nd day - the daily dose is given in 4 doses during the day. Duration of treatment is 3-5 days.

3. Treatment of viral hepatitis . In the complex therapy of viral hepatitis, Polysorb MP is used as a detoxifying agent in usual doses during the first 7-10 days of illness.

4. Allergic diseases .

In case of acute allergic reactions of drug or food origin, preliminary washing of the stomach and intestines with 0.5-1% suspension of Polysorb MP is recommended. Then the drug is given in usual doses until the onset of the clinical effect. For chronic food allergies , courses of Polisorb MP are recommended for 7-10-15 days, the drug is taken immediately before meals. Similar courses are indicated for acute recurrent urticaria and Quincke's edema, eosinophilia, on the eve and against the background of exacerbation of pollinosis and other atopy.

5. Chronic renal failure. They use courses of treatment with Polysorb MP in a daily dose of 0.15-0.2 g / kg body for 25-30 days with a break of 2-3 weeks.

Side effect.

Rarely - allergic reactions, dyspepsia, constipation. With a long, more than 14 days, intake of Polysorb MP, a violation of the absorption of vitamins, calcium is possible, and therefore it is recommended to take prophylactic multivitamin preparations, calcium.

Interaction with other medicines.

It is possible to reduce the therapeutic effect of simultaneously taken orally drugs

Release form. Powder for preparation of oral suspension. 1, 2, 3, 6, 10 and 12 g in disposable bags made of label paper with a thermal layer. 1, 2, 3, 4, 5, 10, 30, 50 or 100 single-use bags together with instructions for use in a cardboard box. It is allowed to place single-use bags directly in the group packaging, instructions are inserted according to the number of bags.

50 g in double polyethylene bags or 5 kg, 10 kg in double polyethylene bags (for hospitals). Package of 50 g in a carton box. Also, 12, 15, 20, 25, 30, 35, 40, 45 and 50 g in cans made of polystyrene, polyethylene or polyethylene terephthalate, sealed with lids of similar materials. Bank with instructions in a cardboard box. Banks of 12 g are allowed to be packaged in shrink film in 5 and 10 pieces, enclosing instructions according to the number of cans.

Shelf life:

5 years. Do not use after the expiration date.

Storage conditions : At a temperature not exceeding 25 ? —. Store in a tightly closed container after opening. Suspension shelf life is no more than 48 hours.

Terms of dispensing from pharmacies:

Without recipe.