Pirindol | Pyrazidol tablets 25 mg, 50 pcs.

Special Price $16.49 Regular Price $25.00
In stock
SKU
BID472716
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Form release

tablets
Form release

tablets

Packing

per pack 50 pcs.

Pharmacological action

Pyrazidol - timoleptic, antidepressant.

Selectively inhibits MAO type A, blocks the deamination of serotonin and norepinephrine, to a lesser extent tyramine. Partially inhibits monoamine reuptake, potentiates the effects of norepinephrine precursor - dioxiphenylalanine (L-dopa) and serotonin precursor - 5-hydroxytryptophan. Stimulates adrenergic and serotonergic structures. Activates the processes of synaptic transmission of nervous excitation in the central nervous system. It has a nootropic effect, improves cognitive function.

Pharmacodynamics

The timoleptic effect is combined with a balanced effect on the central nervous system (activating effect in patients with apathetic, anergic depressions or sedative effect in patients in an agitated state).

Indications

Depression, incl. senile, involutional, occurring mainly with psychomotor inhibition and asthenic disorders, anxiety-depressive or anxiety-delusional components, alcohol withdrawal syndrome, Alzheimer's disease (as part of complex therapy).

Contraindications

Hypersensitivity, acute hepatitis, blood diseases, concomitant use of MAO inhibitors.

Use during pregnancy and lactation

Adequate and strictly controlled studies on the safety and effectiveness of the drug during pregnancy and lactation have not been conducted.

Special instructions

Pyrazidol is not prescribed simultaneously with MAO inhibitor antidepressants, furazolidone, procarbazine, selegiline.

Pirazidol may be used in patients with glaucoma and benign prostatic hyperplasia.

Pyrazidolum is compatible with antipsychotic agents, anxiolytics.

Composition

Active ingredient: pirlindol

Excipients: sugar milk starch potato calcium stearate

Dosage and administration

Inside, at 0.05-0.075 g / day in 2 divided doses, gradually increasing the dose by 0.025-0.05 g to 0.15-0.30 g / day. The maximum daily dose is 0.4 g, divided into 2-3 doses. After the therapeutic effect is achieved, treatment is continued for 2–4 weeks, after which the dose is gradually reduced.

Side effects

Dry mouth, nausea, sweating, hand tremor, tachycardia, dizziness, allergic reactions.

Drug Interactions

Increases the effectiveness of epinephrine (due to antimonoamine oxidase activity). Compatible with antipsychotic drugs, anxiolytics. Incompatible with antidepressants - MAO inhibitors, furazolidone, procarbazine, selegiline.

Storage conditions

In a dry, dark place, at a temperature not exceeding 25 РC.

Term hodnosty

3 years

active substance

Pirlindol

lekarstvennaja form

tablets

Pharmstandard-Leksredstva, Russia

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