Piracetam | Piracetam-SOLOpharm Politvist solution for iv. and w / mouse. enter 200 mg / ml 5 ml ampoules plastic 10 pcs.

Special Price $14.55 Regular Price $22.00
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SKU
BID608276
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Latin name

PIRACETAM
Latin name

PIRACETAM

Release form

Solution for intravenous and intramuscular administration

Pharmacological action of

The active ingredient is piracetam, a cyclic derivative of gamma-aminobutyric acid (GABA).

Piracetam is Nootropica tool that directly affects the brain, improving cognitive (cognitive) processes, such as learning ability, memory, attention, and also mental performance.

Piracetam affects the central nervous system in various ways: by changing the rate of propagation of excitation in the brain, it improves metabolic processes in nerve cells, improves microcirculation, affects the rheological characteristics of the blood without having a vasodilating effect. Improves the connection between the cerebral hemispheres and synaptic conduction in neocortical structures, improves cerebral blood flow.

Piracetam inhibits platelet aggregation and restores the configuration properties of the outer membrane of rigid erythrocytes, as well as the ability of the latter to pass through the vessels of the microvasculature. At a dose of 9.6 g, it reduces the concentration of fibrinogen and von Willebrand factors by 30-40% and lengthens the bleeding time. Piracetam has a protective and restorative effect in case of impaired brain function due to hypoxia and intoxication.

Piracetam reduces the severity and duration of vestibular nystagmus.

Indications

In adults: - symptomatic treatment of psycho-organic syndrome, accompanied by decreased memory, decreased concentration and activity, mood changes, behavioral disorders, impaired gait

- treatment of dizziness (vertigo) and related imbalances (except for vasomotor dizziness and psychogenic origin)

- treatment of cortical myoclonia (monotherapy or as part of complex therapy)

- relief of sickle-cell vaso-occlusion onnogo crisis.

In children: - treatment of dyslexia in children from 8 years old in combination with other

methods - relief of sickle-cell vaso-occlusive crisis.

Contraindications

- severe chronic renal failure (clearance min / min)

stroke - psychomotor agitation

- Huntington's chorea

- pregnancy

- lactation period

Caution: hemostatic disorder extensive surgery heavy bleeding chronic p renal failure (KK 20-80 ml / min).

Use during pregnancy and lactation

Contraindicated in pregnancy and lactation.

Special instructions

Use with caution in patients with impaired hemostasis, before upcoming major surgeries, or in patients with symptoms of severe bleeding.

In the treatment of cortical myoclonia, abrupt cessation of treatment should be avoided, as this may cause a resumption of seizures.

With prolonged therapy in elderly patients, regular monitoring of renal function is recommended, if necessary, dose adjustment is carried out depending on QC.

Penetrates through the filtering membranes of hemodialysis machines.

Influence on the ability to drive vehicles and control mechanisms

During treatment, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Composition

1 amp. piracetam 1 g

Dosage and administration

i.v. in stream or drip, i.v. The daily dose is divided into 2-4 doses.

Symptomatic treatment of the psycho-organic syndrome: 4.8 g / day for the first week, then switch to a maintenance dose of 1.2-2.4 g / day.

Treatment of dizziness and related imbalances: 2.4-4.8 g / day.

Treatment of cortical myoclonia: start with a dose of 7.2 g / day, every 3-4 days the dose is increased by 4.8 g / day until a maximum dose of 24 g / day is reached. Treatment continues throughout the period of the disease. Every 6 months you should try to reduce the dose or cancel the drug, gradually reducing the dose by 1.2 g / day every 2 days. With a slight therapeutic effect or its absence, treatment is stopped.

For sickle-cell vaso-occlusive crisis (in adults and children): iv 300 mg / kg / day divided into 4 equal doses.

Treatment of dyslexia in children over 8 years of age (in combination with other methods of treatment) - 3.2 g each, divided into 2 equal doses.

In chronic renal failure of mild degree (KK 50-79 ml / min) - 2/3 of the dose divided into 2-3 doses of the average degree (KK 30-49 ml / min) - 1/3 of the dose divided into 2 doses of severe (KK 20-30 ml / min) -1/6 doses once.

Side effects

From the side of the central nervous system: motor disinhibition, irritability, drowsiness, depression, asthenia, headache, insomnia, mental agitation, imbalance, ataxia, exacerbation of the course of epilepsy, anxiety, hallucinations, confusion.

From the digestive system: nausea, vomiting, diarrhea, abdominal pain.

Metabolism: weight gain.

On the part of the sensory organs: vertigo.

From the skin: dermatitis, itching, rashes.

Allergic reactions: hypersensitivity, anaphylactic reactions, angioedema.

Local reactions: pain at the injection site, thrombophlebitis. Other: fever, decreased blood pressure.

Drug Interactions

When used simultaneously with iodine-containing thyroid hormones, confusion, irritability, and sleep disturbance may occur. In high doses (9.6 g / day) in patients with venous thrombosis, it increases the anticoagulant effect of indirect anticoagulants (a more pronounced decrease in platelet aggregation, fibrinogen, von Willebrand factor, blood viscosity and plasma).

Pharmaceutically compatible with solutions of dextrose (5%, 10%, 20%), fructose (5%, 10%, 20%), 0.9% sodium chloride solution, Ringer's solution, 20% mannitol solution, hydroxyethyl starch (6%, 10% )

Overdose

Symptoms: abdominal pain, diarrhea with blood admixture.

Treatment: induction of vomiting, gastric lavage, symptomatic therapy, hemodialysis (efficiency 50-60%).

There is no specific antidote.

Storage conditions

Store in a dark place at a temperature not exceeding 25 РC. Store in a place out of the reach of children

shelf life

5 years

Deystvuyushtee substance

Piracetam

Terms and conditions

prescription

Dosage form

injection and infusion

Possible product names

Piracetam-SOLOpharm Politvist solution for iv. and w / mouse. enter 200 mg / ml 5 ml ampoules plastic 10 pcs.

Grotex Ltd. LLC, Russia

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