Picamilon solution for injection 0.05mg / ml, 2ml No. 10

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BIDL3179943
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Expiration Date: 05/2027

Russian Pharmacy name:

Пикамилон раствор для инъекций 0,05мг/мл, 2мл №10

Picamilon solution for injection 0.05mg / ml, 2ml No. 10

Adults:

Chronic cerebrovascular insufficiency (discirculatory encephalopathy, consequences of cerebrovascular accident), condition after traumatic brain injury, vegetative dystonia syndrome, as part of complex therapy for depressive disorders of various origins in old age.

Ј As part of complex treatment for chronic alcoholism (reduction of asthenic, asthenoneurotic, postpsychotic, pre-relapse states in alcoholic encephalopathy).

Ј As part of the complex therapy of primary open-angle glaucoma with compensated intraocular pressure (to stabilize visual function).

Ј As part of the complex therapy of vegetative dystonia syndrome, accompanied by anxiety, fear, increased irritability, asthenia, emotional lability.

To improve the tolerance of physical and mental stress, to increase stress resistance (for persons who are in stressful and extreme conditions of activity; to restore the physical performance of athletes, to increase resistance to physical and mental stress).

Children over 3 years old and adults in urological practice with urination disorders to improve the adaptive function of the bladder (decrease detrusor hypoxia).

Intravenous drip or jet (slow), intramuscular injection.

Before dropwise administration, the contents of the ampoule are dissolved in 200 ml of 0.9% sodium chloride solution.

In chronic cerebrovascular insufficiency: 100-200 mg is administered 1 time per day for 10 days intravenously, then intramuscularly. The course of treatment is 15 - 30 days. When the condition improves, they switch to oral forms in a daily dose of 50-150 mg. A second course - in 5-6 months.

As part of complex therapy in the treatment of depressive conditions of the elderly: 50-200 mg is administered per day for 10-15 days.

In the treatment of chronic alcoholism, 100 mg is administered per day for a course of 6-15 days.

To restore working capacity at increased loads, 200 mg is administered in a daily dose for 10-15 days, for athletes - in the same dose for 14 days of the training period.

As part of the complex therapy of vegetative dystonia syndrome, 100-200 mg is prescribed for 10-15 days.

In the complex treatment of primary open-angle glaucoma, 100-200 mg is administered per day for 10 days.

In the treatment of urinary disorders: 100 mg is injected intramuscularly (for children from 3 to 10 years old), 200 mg per day (for children over 11 years old and adults).

Active substance

Nicotinoyl sodium gamma aminobutyrate - 50 mg and 100 mg

Excipients:

0.1 M hydrochloric acid solution - up to pH 6.7 to 8.0

Water for injection - up to 1 ml

  • Hypersensitivity

  • chronic renal failure,

  • pregnancy,

  • lactation period,

  • children under 3 years of age (in children over 3 years of age, it is used for urination disorders).

Trade name: PicamilonЃ

INN or Generic Name: Nicotinoyl Gamma-Aminobutyric Acid &.

Dosage form: solution for intravenous and intramuscular administration.

Composition:

Active substance

Nicotinoyl sodium gamma aminobutyrate - 50 mg and 100 mg

Excipients:

0.1 M hydrochloric acid solution - up to pH 6.7 to 8.0

Water for injection - up to 1 ml

Description: Transparent colorless or slightly colored liquid.

Pharmacotherapeutic group: nootropic agent.

ATX code: [N06BX]

Pharmacological properties:

Pharmacodynamics:

Nootropic agent, dilates the blood vessels of the brain. It has a tranquilizing and mild psychostimulating effect, antiplatelet and antioxidant effect. Improves the functional state of the brain due to the normalization of tissue metabolism and influence on cerebral circulation (increases the volumetric and linear velocity of cerebral blood flow, has a vasodilating, antiplatelet, antioxidant effect, improves microcirculation). With a course admission, it increases physical and mental performance, reduces headache, improves memory, normalizes sleep; helps to reduce or disappear feelings of anxiety, tension, fear, emotional incontinence. Promotes the restoration of central motor and speech disorders of vascular or traumatic genesis.Improves blood circulation in the vessels of the retina and optic nerve.

Pharmacokinetics:

Absorption is fast and complete with any route of administration. Penetrates through the blood-brain barrier, is retained for a long time in the tissues of the body. Bioavailability is 50-88%. It is excreted mainly by the kidneys unchanged. The half-life is 0.51 hours.

Indications for use:

Adults:

Chronic cerebrovascular insufficiency (discirculatory encephalopathy, consequences of cerebrovascular accident), condition after traumatic brain injury, vegetative dystonia syndrome, as part of complex therapy for depressive disorders of various origins in old age.

Ј As part of complex treatment for chronic alcoholism (reduction of asthenic, asthenoneurotic, postpsychotic, pre-relapse states in alcoholic encephalopathy).

Ј As part of the complex therapy of primary open-angle glaucoma with compensated intraocular pressure (to stabilize visual function).

Ј As part of the complex therapy of vegetative dystonia syndrome, accompanied by anxiety, fear, increased irritability, asthenia, emotional lability.

To improve the tolerance of physical and mental stress, to increase stress resistance (for persons who are in stressful and extreme conditions of activity; to restore the physical performance of athletes, to increase resistance to physical and mental stress).

Children over 3 years old and adults in urological practice with urination disorders to improve the adaptive function of the bladder (decrease detrusor hypoxia).

Contraindications:

  • Hypersensitivity

  • chronic renal failure,

  • pregnancy,

  • lactation period,

  • children under 3 years of age (in children over 3 years of age, it is used for urination disorders).

Application during pregnancy and during breastfeeding:

Due to the fact that the safety of using the drug in pregnant and lactating women has not been established, the use of the drug during pregnancy and during breastfeeding is contraindicated.

Method of administration and dosage:

Intravenous drip or jet (slow), intramuscular injection.

Before dropwise administration, the contents of the ampoule are dissolved in 200 ml of 0.9% sodium chloride solution.

In chronic cerebrovascular insufficiency: 100-200 mg is administered 1 time per day for 10 days intravenously, then intramuscularly. The course of treatment is 15 - 30 days. When the condition improves, they switch to oral forms in a daily dose of 50-150 mg. A second course - in 5-6 months.

As part of complex therapy in the treatment of depressive conditions of the elderly: 50-200 mg is administered per day for 10-15 days.

In the treatment of chronic alcoholism, 100 mg is administered per day for a course of 6-15 days.

To restore working capacity at increased loads, 200 mg is administered in a daily dose for 10-15 days, for athletes - in the same dose for 14 days of the training period.

As part of the complex therapy of vegetative dystonia syndrome, 100-200 mg is prescribed for 10-15 days.

In the complex treatment of primary open-angle glaucoma, 100-200 mg is administered per day for 10 days.

In the treatment of urinary disorders: 100 mg is injected intramuscularly (for children from 3 to 10 years old), 200 mg per day (for children over 11 years old and adults).

Side effect:

Lowering blood pressure, dizziness, headache, mild nausea, irritability, agitation, anxiety, allergic reactions (skin rash, itching).

Overdose:

Strengthening the severity of dose-dependent symptoms of side effects. Treatment is symptomatic.

Interaction with other medicinal products:

It shortens the effect of barbiturates, enhances the effect of narcotic analgesics.

Special instructions:

A negative effect of the drug on the performance of potentially hazardous activities that require special attention and speed of reaction (driving, working with moving mechanisms, etc.) is possible.

Influence on the ability to drive vehicles and mechanisms:

During the period of treatment, care should be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Release form:

Solution for intravenous and intramuscular administration of 50 mg / ml and 100 mg / ml.
2 ml in ampoules made of glass of 1 hydrolytic class with a colored marking ring. 5 ampoules in a blister made of polyvinyl chloride film without foil.
2 blister packs of 5 ampoules, together with instructions for use, are placed in a cardboard box.

Storage conditions:

In a dark place at a temperature not exceeding 25 ? C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiration date indicated on the package.

Vacation conditions:

On prescription.

Manufacturer and organization accepting claims:

Pharmstandard-UfaVITA OJSC, 450077, Russia, Ufa, st. Khudaiberdin, 28,

tel./fax (347) 272 92 85, www.pharmstd.ru

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