phenylbutazone | Butadione tablets 150 mg, 20 pcs.
Special Price
$15.52
Regular Price
$23.00
In stock
SKU
BID473044
Release form
Tablets.
Tablets.
Release form
Tablets.
Packing
20 pcs.
Pharmacological action of
NSAIDs, has anti-inflammatory, analgesic and antipyretic effects associated with the suppression of the activity of COX and COX 2, regulating the synthesis of GHGs. It has a uricosuric effect.
Contraindications
Hypersensitivity complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to ASA or other NSAIDs (including a history of)
erosive and ulcerative ulcer of the gastrointestinal tract in stage 12 and gastrointestinal ulcer duodenal ulcer, ulcerative colitis, peptic ulcer), bone marrow depression, decompensated heart failure or pulmonary heart disease, severe hepatic and / or renal failure (CC less than 30 ml / min), period after coronary artery bypass grafting
progressive kidney disease, active liver disease, confirmed hyperkalemia,
pregnancy (III trimester), active gastrointestinal bleeding, inflammatory bowel disease.
Caution. Hyperbilirubinemia, asthma, heart failure, edema, hypertension, hemophilia, hypocoagulation, liver failure, chronic renal failure, hearing loss, vestibular apparatus pathology, blood diseases, diabetes mellitus, SLE, polymyalgia rheumatica, transient arteritis, gastrointestinal tract ulcer, stomatitis, stomatitis cerebrovascular disease, dyslipidemia / hyperlipidemia, peripheral artery disease, smoking, chronic renal failure (CC 30-60 ml / min), a history of gastrointestinal ulceration, the presence of H. pylori infection,
elderly age, prolonged use of NSAIDs, alcoholism, severe somatic diseases, concomitant use of oral GCS (including prednisone), anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective reuptake inhibitors serotonin (including citalopram, fluoxetine, paroxetine, sertraline),
pregnancy, lactation.
Special instructions
During treatment, monitoring of the picture of peripheral blood and the functional state of the liver and kidneys is necessary.
If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study.
During treatment, you should refrain from engaging in potentially hazardous activities that require increased attention and speed of mental and motor reactions. To reduce the risk of adverse events from the gastrointestinal tract, the minimum effective dose should be used with the minimum possible short course.
Composition
Phenylbutazone 150 mg.
Dosage and administration
Inside, 0.2-0.4 g during or after meals 3-4 times a day.
For children from 6 months old - 0.01-0.1 g (depending on age) 3-4 times a day. The duration of therapy is 2-5 weeks or more.
Side effects of the digestive system: dyspepsia, NSAIDs, gastropathy, abdominal pain, nausea, vomiting, heartburn, diarrhea or constipation with prolonged use in large doses - ulceration of the gastrointestinal mucosa, aphthous stomatitis, glossitis, erosive (gastrointestinal, gingival, hemorrhoidal), impaired liver function.
From the CCC: increased blood pressure, tachycardia.
From the nervous system: headache, dizziness, drowsiness, depression, agitation.
On the part of the sensory organs: hearing loss, tinnitus.
From the side of hematopoietic organs: agranulocytosis, leukopenia, anemia, thrombocytopenia.
Allergic reactions: skin rash, itching, urticaria, bronchospasm, edema syndrome, angioedema.
Other: increased sweating, uterine bleeding.
Drug interaction
Enhances the effect of indirect anticoagulants , antiplatelet agents, fibrinolytics, side effects of GCS and ISS, estrogen, morphine, PASK, penicillin, hypoglycemic effect of sulfonylurea derivatives.
Reduces the effectiveness of uricosuric, antihypertensive drugs and diuretics.
Increases the blood concentration of Li +, methotrexate.
Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, tricyclic antidepressants) increase the production of hydroxylated active metabolites.
Antacids and colestyramine decrease absorption.
Myelotoxic drugs increase the hematotoxicity of the drug.
Overdose
Symptoms: cyanosis of the fingertips, lips, body skin, dizziness, headache, increased or decreased blood pressure, hyperventilation of the lungs, clouding of consciousness, in children - myoclonic cramps, nausea, vomiting, abdominal pain, hemorrhage, impaired function liver and kidney.
Treatment: gastric lavage, the introduction of activated charcoal, symptomatic therapy aimed at maintaining the vital functions of the body. Forced diuresis and hemodialysis are ineffective.
Deystvuyuschee substances
phenylbutazone
Dosage form
tablets
Appointment
Adult, Children over 15 years, For prescribing adults, Pregnant only II trimester for prescription
Indications
neuralgia trigeminal nerve , Sciatica, Osteoarthrosis, Lumbago, Insect Bites, Rheumatoid Arthritis, Arthrosis, Dermatitis, Arthritis, Sunburn, Injuries, Burns, Dislocations and Stretches
Obolensky AF Russian
Tablets.
Packing
20 pcs.
Pharmacological action of
NSAIDs, has anti-inflammatory, analgesic and antipyretic effects associated with the suppression of the activity of COX and COX 2, regulating the synthesis of GHGs. It has a uricosuric effect.
Contraindications
Hypersensitivity complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to ASA or other NSAIDs (including a history of)
erosive and ulcerative ulcer of the gastrointestinal tract in stage 12 and gastrointestinal ulcer duodenal ulcer, ulcerative colitis, peptic ulcer), bone marrow depression, decompensated heart failure or pulmonary heart disease, severe hepatic and / or renal failure (CC less than 30 ml / min), period after coronary artery bypass grafting
progressive kidney disease, active liver disease, confirmed hyperkalemia,
pregnancy (III trimester), active gastrointestinal bleeding, inflammatory bowel disease.
Caution. Hyperbilirubinemia, asthma, heart failure, edema, hypertension, hemophilia, hypocoagulation, liver failure, chronic renal failure, hearing loss, vestibular apparatus pathology, blood diseases, diabetes mellitus, SLE, polymyalgia rheumatica, transient arteritis, gastrointestinal tract ulcer, stomatitis, stomatitis cerebrovascular disease, dyslipidemia / hyperlipidemia, peripheral artery disease, smoking, chronic renal failure (CC 30-60 ml / min), a history of gastrointestinal ulceration, the presence of H. pylori infection,
elderly age, prolonged use of NSAIDs, alcoholism, severe somatic diseases, concomitant use of oral GCS (including prednisone), anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective reuptake inhibitors serotonin (including citalopram, fluoxetine, paroxetine, sertraline),
pregnancy, lactation.
Special instructions
During treatment, monitoring of the picture of peripheral blood and the functional state of the liver and kidneys is necessary.
If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study.
During treatment, you should refrain from engaging in potentially hazardous activities that require increased attention and speed of mental and motor reactions. To reduce the risk of adverse events from the gastrointestinal tract, the minimum effective dose should be used with the minimum possible short course.
Composition
Phenylbutazone 150 mg.
Dosage and administration
Inside, 0.2-0.4 g during or after meals 3-4 times a day.
For children from 6 months old - 0.01-0.1 g (depending on age) 3-4 times a day. The duration of therapy is 2-5 weeks or more.
Side effects of the digestive system: dyspepsia, NSAIDs, gastropathy, abdominal pain, nausea, vomiting, heartburn, diarrhea or constipation with prolonged use in large doses - ulceration of the gastrointestinal mucosa, aphthous stomatitis, glossitis, erosive (gastrointestinal, gingival, hemorrhoidal), impaired liver function.
From the CCC: increased blood pressure, tachycardia.
From the nervous system: headache, dizziness, drowsiness, depression, agitation.
On the part of the sensory organs: hearing loss, tinnitus.
From the side of hematopoietic organs: agranulocytosis, leukopenia, anemia, thrombocytopenia.
Allergic reactions: skin rash, itching, urticaria, bronchospasm, edema syndrome, angioedema.
Other: increased sweating, uterine bleeding.
Drug interaction
Enhances the effect of indirect anticoagulants , antiplatelet agents, fibrinolytics, side effects of GCS and ISS, estrogen, morphine, PASK, penicillin, hypoglycemic effect of sulfonylurea derivatives.
Reduces the effectiveness of uricosuric, antihypertensive drugs and diuretics.
Increases the blood concentration of Li +, methotrexate.
Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, tricyclic antidepressants) increase the production of hydroxylated active metabolites.
Antacids and colestyramine decrease absorption.
Myelotoxic drugs increase the hematotoxicity of the drug.
Overdose
Symptoms: cyanosis of the fingertips, lips, body skin, dizziness, headache, increased or decreased blood pressure, hyperventilation of the lungs, clouding of consciousness, in children - myoclonic cramps, nausea, vomiting, abdominal pain, hemorrhage, impaired function liver and kidney.
Treatment: gastric lavage, the introduction of activated charcoal, symptomatic therapy aimed at maintaining the vital functions of the body. Forced diuresis and hemodialysis are ineffective.
Deystvuyuschee substances
phenylbutazone
Dosage form
tablets
Appointment
Adult, Children over 15 years, For prescribing adults, Pregnant only II trimester for prescription
Indications
neuralgia trigeminal nerve , Sciatica, Osteoarthrosis, Lumbago, Insect Bites, Rheumatoid Arthritis, Arthrosis, Dermatitis, Arthritis, Sunburn, Injuries, Burns, Dislocations and Stretches
Obolensky AF Russian
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