Pharmacef DC (Farmacefum DC) syringe dispenser 5g

DESCRIPTION

Pharmacef DC (Farmacefum DC) is a veterinary drug used for the prevention (instantaneous start) of mastitis and the treatment of cows with mastitis. In appearance, the drug is an oily suspension from white to cream color.

COMPOSITION

One syringe (5.0 g) contains 383.5 mg of cefapirin benzathine salt (respectively 300.0 mg of cefapirin), excipients, base up to 5.0 g.

PHARMACOLOGICAL PROPERTIES

Cefapirin, which is part of the drug, belongs to the first generation antibiotics of the cephalosporin group.

Cefapirin has a wide spectrum of bactericidal action against many gram-positive and gram-negative aerobic, facultative anaerobic and anaerobic bacteria, such as: Arcanobacterium pyogenes, Escherichia coli, Klebsiella spp., Staphylococcus aureus, Staphylococcus aureus, Streptocoeccus, dysgalactia spp. , Corynebacterium bovis, Proteus vulgaris, Clostridium perfringens and other pathogens of mastitis, with the exception of enterococci.

The drug is resistant to the action of penicillinase and retains its activity under anaerobic and aerobic conditions.

Cefapirin has a bactericidal effect on microorganisms in the growth phase. The antibacterial effect is associated with the specific ability of cefapirin to inhibit the biosynthesis of peptoglycan of the wall of microorganisms, which leads to their death.

When administered intracisternally, cefapirin is poorly absorbed, providing high antibacterial concentrations of the drug in the udder tissues for a long time. After application of the drug during the dry period, a high concentration of the active substance in the secretion of the udder remains for 16 - 28 days.

DOSAGE AND APPLICATION

Pharmacef DC is used for the prophylaxis (instant start) of mastitis and the treatment of cows with mastitis in the dry period caused by microorganisms sensitive to cephalosporin antibiotics.

The drug is administered intracisternally for prophylactic purposes in healthy, and for therapeutic purposes in the affected quarters of the udder, once, after the last milking before transfer to the dry period, but no later than 35 days before the expected calving, in a dose the contents of one syringe (5 g) one quarter of the udder.

Before using the syringe with the drug, it is recommended to shake it thoroughly, and if necessary, warm it up to the body temperature of the animal.

Before the introduction of the drug, completely empty the udder quarters from the contents; treat the skin of the nipple with an antiseptic (cleaning cloth); remove the cap from the syringe cannula, insert the cannula into the nipple canal and completely squeeze the contents of the syringe into each quarter of the udder. Then the cannula of the syringe is removed from the nipple canal and the nipple is clamped with fingers for 1 - 2 minutes. A gentle massage of the nipple is carried out from the bottom up to better distribute the drug.

SPECIAL INSTRUCTIONS

If allergic reactions occur, the drug should be discontinued, antihistamines (allervet, diprazine) and calcium preparations (calcium chloride or calcium gluconate) should be prescribed.

After calving, milk is used for food purposes without restrictions. Slaughter of animals for meat is allowed no earlier than 14 days after the last use of the drug. In the event of the forced slaughter of animals before the established date, the meat is used to feed fur-bearing animals.

CONTRAINDICATIONS

Pharmacef DC must not be used during lactation and less than 35 days before calving. The use of the drug is contraindicated in animals with hypersensitivity to antibiotics of the cephalosporin and penicillin series.

SIDE EFFECTS

When using the drug in the recommended doses in accordance with the instructions, side reactions and complications are not observed.

SHELF LIFE AND STORAGE

The drug is stored according to list B in a dry, dark place at a temperature from plus 5 В° C to plus 25 В° C. The shelf life of the drug is 2 years from the date of manufacture, subject to the rules of storage and transportation.

PACKAGING

The drug is produced in dispensing syringes made of polymeric material with a nominal weight of 5 g.

Specifications

KolVUP

60

Manufacturer

Belarus

Temperature regime

from +5 to +25

Teaser

used for the prevention (instant start) of mastitis and the treatment of cows with mastitis