Peptydov brain complex | Cerebrolysin injection solution 10 ml ampoules 5 pcs.

Special Price $40.74 Regular Price $50.00
In stock
SKU
BID462163
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Latin name

Cerebrolysin
Latin name

Cerebrolysin

Release form

Injection solution

Packing

5 ampoules of 10 ml.

Indications

Alzheimer's disease

dementia syndrome of various origins

chronic cerebrovascular insufficiency

ischemic stroke

traumatic brain injury and spinal cord

delayed mental development in children with attention-deficiency and high-grade treatment

Contraindications

individual intolerance to the drug

acute renal failure

status epilepticus.

Use during pregnancy and lactation

With caution, the drug is prescribed in the first trimester of pregnancy and during lactation.

During pregnancy and during breastfeeding, Cerebrolysin should be used only after a thorough analysis of the relationship between the positive effect of treatment and the risk associated with its implementation. The results of experimental studies do not suggest that Cerebrolysin has a teratogenic effector has a toxic effect on the fetus. However, no similar clinical studies have been conducted.

Composition

Active ingredient: 1 ml of an aqueous solution of the drug contains 215.2 mg of cerebrolysin concentrate (a complex of peptides derived from a pig’s brain). The active fraction of Cerebrolysin is represented by peptides, whose molecular weight does not exceed 10,000 daltons.

Excipients sodium hydroxide and water for injection.

Dosage and administration

Intramuscularly (up to 5 ml), intravenously (up to 10 ml), intravenously, by slow infusion (from 10 to 50 ml).

Doses and duration of treatment depend on the nature and severity of the disease, as well as on the age of the patient. It is possible to prescribe single doses, the value of which can reach 50 ml, however, treatment is more preferred. The recommended optimal course of treatment is daily injections for 10–20 days.

Acute conditions (ischemic stroke, head injury, complications after neurosurgical operations) - from 10 to 50 ml.

The residual period of stroke and traumatic damage to the brain and spinal cord is from 5 to 50 ml.

Psycho-organic syndrome and depression - from 5 to 30 ml.

Alzheimer's disease, dementia of vascular and combined Alzheimer's vascular origin - from 5 to 30 ml.

In neuropediatric practice - 0.1-0.2 ml / kg.

To increase the effectiveness of treatment, repeated courses may be carried out until an improvement in the patient's condition due to treatment is observed. After the first course, the frequency of administration of doses can be reduced to 2 or 3 times a week.

Doses of 10 to 50 ml are recommended to be administered only by slow intravenous infusion after dilution with the proposed standard solutions for infusion. The duration of infusion is from 15 to 60 minutes.

Side effects

Reaction to administration: if administered too quickly, in rare cases there may be a sensation of fever, sweating, dizziness in isolated cases - heart palpitations or arrhythmias. Therefore, the drug should be administered slowly.

From the gastrointestinal tract: rarely - loss of appetite, dyspepsia, diarrhea, constipation, nausea and vomiting.

From the side of the central nervous system and peripheral nervous system: in rare cases, the expected effect of activation was accompanied by excitation (manifested aggressive behavior, confusion, insomnia). There are reports of occurrence in isolated cases (

On the part of the immune system: extremely rarely - hypersensitivity reactions or allergic reactions, manifested by headache, pain in the neck, limbs, lower back, shortness of breath, chills and collapsoid state.

Local reactions: rarely - redness of the skin, itching and burning at the injection site

Other: extremely rare - according to the results of studies, cases of hyperventilation, arterial hypertension, arterial hypotension, fatigue, tremor, depression, apathy, dizziness, and flu-like symptoms (cough, runny nose, respiratory tract infections).

It should be noted that some undesirable effects (agitation, arterial hypertension, arterial hypotension, lethargy, tremor, depression, apathy, dizziness, headache, shortness of breath, diarrhea, nausea) were detected during clinical trials and occurred equally in patients treated with cerebrolysin and in placebo patients.

Drug Interaction

Given the pharmacological profile of Cerebrolysin, particular attention should be paid to possible additive effects when co-administered with antidepressants, incl. MAO inhibitors. In such cases, it is recommended to reduce the dose of the antidepressant.

Do not mix in one solution for infusion Cerebrolysin and balanced amino acid solutions.

Cerebrolysin is incompatible with solutions, which include lipids, and with solutions that change the pH of the medium (5–8).

Storage conditions

The product should be stored in a dark place at a temperature not exceeding 25 РC.

Shelf life

5 years.

Active ingredient

Brain peptides complex

dosage form

injection

Possible product names

CEREBROLYSINE 10ML N5 RLL 10 AML N5 AMP RR D / IN

Cerebrolysin 10ml rd r / in. Amp. X5 B M (R)

Cerebrolysin 10ml solution d / injection Amp. X5 (R)

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