Paracetamol, Phenylephrine, Phenyramine, Ascorbic acid | GrippoFlu Extra sachets with currant flavor 13 g, 8 pcs.

Special Price $16.56 Regular Price $27.00
In stock
SKU
BID516097
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Product form

powder for solution for oral solution
Product form

powder for solution for oral solution

Packaging

13 g each in heat sealable bags from a combination material.

For 8 packets in packs of cardboard boxed.

Pharmacological action

Combined drug. Paracetamol is a non-narcotic analgesic, affects the centers of pain and thermoregulation. It has an analgesic and antipyretic effect. Reduces headaches and muscle aches, fever, softens sore throats.

Pheniramine - a blocker of H1-histamine receptors, an anti-allergic agent, reduces rhinorrhea and lacrimation, eliminates spastic phenomena.

Phenylephrine - an adrenergic agonist with moderate vasoconstrictor action, reduces nasal congestion and facilitates breathing through the nose.

Ascorbic acid (vitamin C) makes up for the increased need for vitamin C for colds and flu, especially in the initial stages of the disease. Increases the body's resistance to infectious diseases.

Indications

Symptomatic treatment of colds, flu, SARS (fever, pain, rhinorrhea).

Contraindications

taking drugs containing substances that are part of the drug hypersensitivity to paracetamol and other components that make up the drug while taking tricyclic antidepressants, monoamine oxidase inhibitors (MAOs), beta-blockers pregnancy, lactation, children's age (up to 15 years). Portal hypertension, alcoholism, liver and / or renal failure, deficiency of the enzyme glucose-6-phosphate dehydrogenase.

Precautions

Severe coronary arteriosclerosis, arterial hypertension, thyrotoxicosis, pheochromocytoma, diabetes mellitus, bronchial asthma, chronic obstructive pulmonary disease, blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson gland, and Prostate gland).

Special instructions

During treatment, it is necessary to refrain from drinking alcohol (it may develop hepatotoxic effects), driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition

1 sachet contains paracetamol - 0.650 g of phenylephrine hydrochloride - 0,010 g, pheniramine maleate - 0.020 g ascorbic acid - 0.050 g

Excipients: [sucrose (sugar), citric acid, sodium citrate dihydrate, calcium phosphate trisubstituted (calcium phosphate), titanium dioxide, Black Currant flavoring, azorubine (acid red 2C for pharmaceutical purposes) ( for berry)].

Directions for use and dose

add one package to the glass, pour hot water, mix until completely dissolved and drink. It is necessary to take the drug 1 to 2 hours after eating. Adults and children over 15 years of age: take one packet 3-4 times a day with intervals between doses of 4-6 hours. The maximum daily dose is 4 packets. The course of treatment is not more than 5 days.

Side effects

Allergic reactions (including skin rash, itching, urticaria, angioedema), dizziness, falling asleep, increased irritability, mydriasis, dry mouth, urinary retention, paresis of arterial pressure, increased intraocular pressure, increased intraocular pressure, increased intraocular pressure, increased intraocular pressure, increased intraocular pressure, , nausea, vomiting, epigastric pain anemia, thrombocytopenia, agranulocytosis bronchial obstruction. With prolonged use in large doses, hepatotoxic effect, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia nephrotoxicity (papillary necrosis).

Drug Interactions

The risk of developing the hepatotoxic effects of paracetamol is increased with the simultaneous administration of barbiturates, diphenin, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes.

Enhances the effects of MAO inhibitors, sedatives, ethanol.

Ethanol enhances the sedative effect of antihistamines.

antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, and constipation.

Glucocorticosteroids increase the risk of developing increased intraocular pressure.

Paracetamol reduces the effectiveness of uricosuric drugs and increases the effectiveness of indirect anticoagulants.

Tricyclic antidepressants enhance the sympathomimetic effect of phenylephrine, the simultaneous administration of halothane increases the risk of ventricular arrhythmia.

Reduces the hypotensive effect of guanethidine, which in turn enhances the alpha-adrenostimulatory activity of phenylephrine.

Overdose

Possible: pale skin, anorexia, nausea, vomiting hepatonecrosis increased activity of hepatic transaminases, increase in prothrombin time. In the event of overdose, you should urgently see a doctor.

Treatment: gastric lavage followed by administration of activated charcoal symptomatic therapy, administration of methionine in 8-9 h after overdose and N-acetylcysteine ​​- after 12 h

Storage Conditions

In a dry, dark place at a temperature not exceeding 30 РC.

Shelf life

2 years.

Active ingredient

Paracetamol, Phenylephrine, Phenyramine, Ascorbic acid

Pharmacy terms

No prescription

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