Paracetamol, phenylephrine, ascorbic acid | Colds Blackcurrant sachets 5 g, 5 pcs.

Special Price $17.46 Regular Price $25.00
In stock
SKU
BID469314
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Release form

Powder for solution for oral administration.
Release form

Powder for solution for oral administration.

Packaging

5 sachets of 5 g each.

Pharmacological action

Remedy for the symptoms of colds and acute respiratory infections.

Analgesic non-narcotic drug + alpha-adrenergic agonist + vitamin.

Combined remedy, the action of which is due to its constituent components, has:

Antipyretic.

Analgesic.

A vasoconstrictor effect.

Eliminates common cold symptoms.

Constricts the nasal vessels, eliminates swelling of the mucous membrane of the nasal cavity and nasopharynx, and replenishes vitamin C deficiency in colds.

Onset of action 20-30 minutes after administration, duration 4-4.5 hours.

Indications

Effectively relieve symptoms of the common cold and flu:

Fever.

Headache.

Chills.

Sensation of nasal congestion.

Sore throat when swallowing.

Contraindications

Concomitant use of other paracetamol-containing drugs.

Hypersensitivity to the ingredients that make up the drug.

Thyrotoxicosis.

Diseases of the cardiovascular system: severe aortic stenosis, acute myocardial infarction, tachyarrhythmia.

Arterial hypertension.

Diabetes mellitus.

Pheochromocytoma.

Prostate hyperplasia.

Angle-closure glaucoma.

Concomitant use of tricyclic antidepressants, beta-blockers, monoamine oxidase inhibitors (including within 14 days after they are canceled).

Children under 14 years old.

Pregnancy.

Lactation.

Precautions:

Renal failure.

Hepatic failure.

Congenital hyperbilirubinemia: Gilbert, Dabin-Johnson, Rotor syndromes.

Chronic obstructive pulmonary disease.

Old age.

Deficiency of glucose-6-phosphate dehydrogenase.

Diseases of the blood.

Use during pregnancy and lactation

Contraindicated in pregnancy and during breastfeeding.

Special instructions

Other medicines containing paracetamol, as well as other non-narcotic analgesics, non-steroidal anti-inflammatory drugs (metamizole, acetylsalicylic acid, ibuprofen), barbiturates, antiepileptic drugs, rif, should not be used simultaneously.

Concomitant use of other medicines should be agreed with the doctor.

Distorts the results of laboratory tests evaluating plasma glucose and uric acid concentrations.

Dosage and administration

Pour the contents of one packet into a glass.

Fill it with hot water.

Stir until completely dissolved.

Add sugar or honey to taste (optional).

Adults and children over 14 years of age: take one packet every 4-6 hours, but not more than 4 packets within 24 hours.

The drug is not recommended for more than five days without consulting a doctor.

If symptoms persist, consult a doctor.

Side effects

Allergic reactions: sometimes - skin rash, itching, urticaria, angioedema.

From the hemopoietic system: rarely - thrombocytopenia, leukopenia, agranulocytosis.

From the digestive system: rarely - nausea, vomiting, epigastric pain.

Other: rarely - increased intraocular pressure, urinary retention.

With prolonged use in excess of the recommended dose, hepatotoxic and nephrotoxic effects may be observed.

Phenylephrine hydrochloride may cause nausea, headache, increased blood pressure rarely - a feeling of palpitations. These symptoms disappear after discontinuation of the drug.

Drug Interactions

Stimulators of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites of paracetamol, which makes it possible to develop severe intoxications with small intoxications.

Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatotoxicity.

Paracetamol enhances the effects of MAO inhibitors, sedatives, ethanol.

Ethanol contributes to the development of acute pancreatitis.

Antidepressants, antiparkinsonian, antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, and constipation.

corticosteroids increase the risk of developing glaucoma.

Phenylephrine reduces the hypotensive effect of guanethidine.

Guanethidine enhances the alpha adrenostimulating effect, and tricyclic antidepressants enhance the sympathomimetic effects of phenylephrine.

The drug reduces the effectiveness of uricosuric drugs.

When delaying gastric emptying (propantheline), a slow onset of the drug may occur.

When accelerating the emptying of the stomach (metoclopramide), the drug begins to act faster.

The drug may enhance the effect of indirect anticoagulants.

Overdose

An overdose of paracetamol is apparent after taking 10-15 g (15-20 bags of Prostudox).

Symptoms: epigastric discomfort, nausea, vomiting, paleness of the skin, decreased appetite, nausea, vomiting, hepatonecrosis (the severity of necrosis directly depends on the degree of overdose), increased activity of hepatic transaminases, increase in prothrombosis time48 (48) ), a detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely, impaired liver function develops rapidly and may be complicated by renal failure (renal tubular necrosis).

Treatment: symptomatic, gastric lavage, administration of SH-group donors and precursors for glutathione-methionine synthesis 8-9 h after overdose and N-acetylcysteine ​​after 12 h. The need for additional therapeutic measures (further administration of methionine, in / in the introduction of N-acetylcysteine) is determined by concentration paracetamol in the blood, as well as the time elapsed after its administration.

Storage Conditions

The product should be stored out of reach of children, in a dry, dark place at a temperature not exceeding 25 РC.

shelf life

3 years

Deystvuyushtee substance

paracetamol Fenilэfrin, Askorbinovaya Chisloth

Terms and conditions

without prescription

Possible product names

PROSTUDOX 5.0 N5 PACK POR D / R-RA / CHERN SMOROD /

Prostudox 5g Por. d / prg. r-ra d / pr.vn. (taste of black currant.) X5

PROSTUDOX POR. Prigot. R-RA D / BH. RECEPTION 5G PAK. No. 5

Prostudox powder d / pr. r-ra d / pr inside the pack. 5g N5 Russia

Prostudox Blackcurrant sachets 5 g, 5 pcs.

Synthesis AKOMP, Russia

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