Paracetamol, phenylephrine, ascorbic acid | Colds Blackcurrant sachets 5 g, 10 pcs.
Special Price
$18.43
Regular Price
$27.00
In stock
SKU
BID469315
Latin name
Prostudox
Prostudox
Latin name
Prostudox
Release form
Prostudox. Powder for oral solution.
Packaging
5 g - disposable bags (10) - packs of cardboard.
Pharmacological action
Means for eliminating the symptoms of colds and acute respiratory infections.
Analgesic non-narcotic drug + alpha-adrenergic agonist + vitamin.
Combined remedy, the action of which is due to its constituent components, has:
Antipyretic.
Analgesic.
A vasoconstrictor effect.
Eliminates common cold symptoms.
Narrows the vessels of the nose, eliminates swelling of the mucous membrane of the nasal cavity and nasopharynx, makes up for vitamin C deficiency in colds.
Onset of action 20-30 minutes after ingestion, duration 4-4.5 hours.
Indications
Effectively relieve symptoms of the common cold and flu:
Elevated temperature.
Headache.
Chills.
Sensation of nasal congestion.
Sore throat when swallowing.
Contraindications
Concomitant use of other paracetamol-containing drugs.
Hypersensitivity to ingredients, part of the drug.
Thyrotoxicosis.
Diseases of the cardiovascular system: severe aortic stenosis, acute myocardial infarction, tachyarrhythmia.
Arterial hypertension.
Diabetes mellitus.
Pheochromocytoma.
Prostate hyperplasia.
Angle-closure glaucoma.
Concomitant use of tricyclic antidepressants, beta-blockers, monoamine oxidase inhibitors (including within 14 days after they are canceled).
Children under 14 years old.
Pregnancy.
Lactation.
Precautions:
Renal failure.
Hepatic failure.
Congenital hyperbilirubinemia: Gilbert, Dabin-Johnson, Rotor syndromes.
Chronic obstructive pulmonary disease.
Old age.
Deficiency of glucose-6-phosphate dehydrogenase.
Diseases of the blood.
Use during pregnancy and lactation
Contraindicated in pregnancy and during breastfeeding.
Composition
Active ingredients:
paracetamol 750 mg,
phenylephrine hydrochloride 10 mg,
ascorbic acid 60 mg
Excipients:
sodium citrate penta citric acid penta citric acid penta sodium saccharinate (sodium saccharin),
currant flavor (black currant powder food flavor),
sugar - up to 5 g.
Dosage and administration
Pour the contents of one packet into a glass.
Fill it with hot water.
Stir until completely dissolved.
Add sugar or honey to taste (optional).
Adults and children over 14 years of age: take one packet every 4-6 hours, but not more than 4 packets within 24 hours.
The drug is not recommended for more than five days without consulting a doctor.
If symptoms persist, consult a doctor.
Side effects
Allergic reactions: sometimes - skin rash, itching, urticaria, angioedema.
From the hemopoietic system: rarely - thrombocytopenia, leukopenia, agranulocytosis.
From the digestive system: rarely - nausea, vomiting, epigastric pain.
Other: rarely - increased intraocular pressure, urinary retention.
With prolonged use in excess of the recommended dose, hepatotoxic and nephrotoxic effects may be observed.
Phenylephrine hydrochloride may cause nausea, headache, increased blood pressure rarely - a feeling of palpitations. These symptoms disappear after discontinuation of the drug.
Drug Interaction
Stimulants of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites of paracetamol, which makes it possible to develop severe intoxication with small overdoses.
Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxic action of the drug.
Paracetamol enhances the effects of MAO inhibitors, sedatives, ethanol.
Ethanol promotes acute pancreatitis.
Antidepressants, antiparkinsonian, antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation.
ACS increase the risk of developing glaucoma.
Phenylephrine reduces the hypotensive effect of guanethidine.
Guanetidine enhances alpha-adrenostimulating effect, and tricyclic antidepressants have the sympathomimetic effects of phenylephrine.
The drug reduces the effectiveness of uricosuric drugs.
Slow gastric emptying (propantheline) may cause a delayed onset of the drug.
With acceleration of gastric emptying (metoclopramide), the drug begins to act faster.
The drug can enhance the effect of indirect anticoagulants.
Overdose
An overdose of paracetamol appears after taking 10-15 g (15-20 bags of Prostudox).
Symptoms: epigastric discomfort, nausea, vomiting, paleness of the skin, decreased appetite, nausea, vomiting, hepatonecrosis (the severity of necrosis directly depends on the degree of overdose), increased activity of hepatic transaminases, increase in prothrombosis time48 (48) ), a detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely, impaired liver function develops rapidly and may be complicated by renal failure (renal tubular necrosis).
Treatment: symptomatic, gastric lavage, administration of SH-group donors and precursors of glutathione-methionine synthesis 8-9 h after overdose and N-acetylcysteine after 12 h. Need for additional therapeutic measures (further administration of methionine, N / - acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as the time elapsed after its administration.
Storage conditions
The drug should be stored out of the reach of children, in a dry, dark place at a temperature of no higher than 25 РC.
Expiration
3 years.
Deystvuyuschee substances
Paracetamol, phenylephrine, ascorbic acid
pharmacy terms and conditions Over-the-counter
dosage form
dosage form for administration
srdlprd srdlprd solution srdlprd
srdlpp dl solution
Prostudox
Release form
Prostudox. Powder for oral solution.
Packaging
5 g - disposable bags (10) - packs of cardboard.
Pharmacological action
Means for eliminating the symptoms of colds and acute respiratory infections.
Analgesic non-narcotic drug + alpha-adrenergic agonist + vitamin.
Combined remedy, the action of which is due to its constituent components, has:
Antipyretic.
Analgesic.
A vasoconstrictor effect.
Eliminates common cold symptoms.
Narrows the vessels of the nose, eliminates swelling of the mucous membrane of the nasal cavity and nasopharynx, makes up for vitamin C deficiency in colds.
Onset of action 20-30 minutes after ingestion, duration 4-4.5 hours.
Indications
Effectively relieve symptoms of the common cold and flu:
Elevated temperature.
Headache.
Chills.
Sensation of nasal congestion.
Sore throat when swallowing.
Contraindications
Concomitant use of other paracetamol-containing drugs.
Hypersensitivity to ingredients, part of the drug.
Thyrotoxicosis.
Diseases of the cardiovascular system: severe aortic stenosis, acute myocardial infarction, tachyarrhythmia.
Arterial hypertension.
Diabetes mellitus.
Pheochromocytoma.
Prostate hyperplasia.
Angle-closure glaucoma.
Concomitant use of tricyclic antidepressants, beta-blockers, monoamine oxidase inhibitors (including within 14 days after they are canceled).
Children under 14 years old.
Pregnancy.
Lactation.
Precautions:
Renal failure.
Hepatic failure.
Congenital hyperbilirubinemia: Gilbert, Dabin-Johnson, Rotor syndromes.
Chronic obstructive pulmonary disease.
Old age.
Deficiency of glucose-6-phosphate dehydrogenase.
Diseases of the blood.
Use during pregnancy and lactation
Contraindicated in pregnancy and during breastfeeding.
Composition
Active ingredients:
paracetamol 750 mg,
phenylephrine hydrochloride 10 mg,
ascorbic acid 60 mg
Excipients:
sodium citrate penta citric acid penta citric acid penta sodium saccharinate (sodium saccharin),
currant flavor (black currant powder food flavor),
sugar - up to 5 g.
Dosage and administration
Pour the contents of one packet into a glass.
Fill it with hot water.
Stir until completely dissolved.
Add sugar or honey to taste (optional).
Adults and children over 14 years of age: take one packet every 4-6 hours, but not more than 4 packets within 24 hours.
The drug is not recommended for more than five days without consulting a doctor.
If symptoms persist, consult a doctor.
Side effects
Allergic reactions: sometimes - skin rash, itching, urticaria, angioedema.
From the hemopoietic system: rarely - thrombocytopenia, leukopenia, agranulocytosis.
From the digestive system: rarely - nausea, vomiting, epigastric pain.
Other: rarely - increased intraocular pressure, urinary retention.
With prolonged use in excess of the recommended dose, hepatotoxic and nephrotoxic effects may be observed.
Phenylephrine hydrochloride may cause nausea, headache, increased blood pressure rarely - a feeling of palpitations. These symptoms disappear after discontinuation of the drug.
Drug Interaction
Stimulants of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites of paracetamol, which makes it possible to develop severe intoxication with small overdoses.
Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxic action of the drug.
Paracetamol enhances the effects of MAO inhibitors, sedatives, ethanol.
Ethanol promotes acute pancreatitis.
Antidepressants, antiparkinsonian, antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation.
ACS increase the risk of developing glaucoma.
Phenylephrine reduces the hypotensive effect of guanethidine.
Guanetidine enhances alpha-adrenostimulating effect, and tricyclic antidepressants have the sympathomimetic effects of phenylephrine.
The drug reduces the effectiveness of uricosuric drugs.
Slow gastric emptying (propantheline) may cause a delayed onset of the drug.
With acceleration of gastric emptying (metoclopramide), the drug begins to act faster.
The drug can enhance the effect of indirect anticoagulants.
Overdose
An overdose of paracetamol appears after taking 10-15 g (15-20 bags of Prostudox).
Symptoms: epigastric discomfort, nausea, vomiting, paleness of the skin, decreased appetite, nausea, vomiting, hepatonecrosis (the severity of necrosis directly depends on the degree of overdose), increased activity of hepatic transaminases, increase in prothrombosis time48 (48) ), a detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely, impaired liver function develops rapidly and may be complicated by renal failure (renal tubular necrosis).
Treatment: symptomatic, gastric lavage, administration of SH-group donors and precursors of glutathione-methionine synthesis 8-9 h after overdose and N-acetylcysteine after 12 h. Need for additional therapeutic measures (further administration of methionine, N / - acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as the time elapsed after its administration.
Storage conditions
The drug should be stored out of the reach of children, in a dry, dark place at a temperature of no higher than 25 РC.
Expiration
3 years.
Deystvuyuschee substances
Paracetamol, phenylephrine, ascorbic acid
pharmacy terms and conditions Over-the-counter
dosage form
dosage form for administration
srdlprd srdlprd solution srdlprd
srdlpp dl solution
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