Pancreatin | Mezim 20000 tablets, coated with quiche-sol. shell 20 pcs.

Special Price $17.46 Regular Price $25.00
In stock
SKU
BID483452
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Release form

Enteric-coated tablets
Release form

Enteric-coated tablets

Packing

20 pcs. packaged.

Pharmacological action

Digestive enzyme agent.

Pancreatin is a porcine pancreatic powder.

Pancreatic enzymes that make up pancreatin have a proteolytic, amylolytic and lipolytic effect and promote the breakdown of proteins, fats, carbohydrates, improve the functional state of the gastrointestinal tract (GIT), normalize digestion processes

Mezim tablets 20,000 are coated with an acid-resistant solution under the influence of hydrochloric acid of the stomach and, thus, protects the enzymes contained in the preparation from inactivation. Dissolution of the membrane and the release of enzymes occurs at pH close to neutral or slightly alkaline.

Indications

Initial Alzheimer's type dementia (Alzheimer's disease) and cerebrovascular dementia

Peripheral neuropathy of various etiologies

Primary and secondary involutional syndromes against the background of vascular encephalopathies, mental focus and memory efficiency.accuracy of exocrine pancreatic function (chronic pancreatitis, cystic fibrosis, etc.)

Chronic inflammatory and dystrophic diseases of the stomach, intestines, liver, gall bladder

Conditions after resection or irradiation of the gastrointestinal tract, accompanied by disturbances in digestion, flatulence, combined diarrhea ( )

To improve the digestion of food in patients with normal gastrointestinal function in case of nutritional errors

Preparation for radiological and ul razvukovomu study abdominal

gastrointestinal disorders functional character (acute intestinal infections, irritable bowel syndrome, etc.).

Contraindications

Hypersensitivity to any of the components of the drug

Acute pancreatitis or chronic pancreatitis in the acute stage. Nevertheless, it is possible to use in the phase of a decaying exacerbation with the expansion of the diet, if there are signs of digestion

Hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome

Children under 3 years of age (for this dosage form).

Use during pregnancy and lactation

Before using Mezim® 20000, if you are pregnant or suspect that you might be pregnant or are planning a pregnancy, you should consult your doctor.

During breastfeeding, you should consult your doctor before using Mezim® 20000.

Data on the use of pancreatin during pregnancy and during breastfeeding are not available.

During pregnancy and during breastfeeding, prescribing pancreatin by your doctor is possible only if the intended benefit to the mother outweighs the possible risk to the fetus or baby.

Special instructions

In acute pancreatitis or exacerbation of chronic pancreatitis (at the stage of exacerbation decay), during restorative dietary nutrition, it is advisable to prescribe Mezim 20,000 against the background of pancreatic function that is taking place or remains in the future.

Composition

Active ingredient:

Pancreatin * - 220.00 - 293.34 mg with minimal activity:

lipase 20,000 units

amylase 12000 units

proteases 900 units

Excipients: lactic acid cellulose, cellulose, cellulose, mono-cellulose, mono-cellulose, cellulose (type A), magnesium stearate.

Shell: hypromellose, methacrylic acid and ethyl acrylate copolymer (1: 1), dispersion 30% (dry weight), triethyl citrate, talc, titanium dioxide (E 171), simethicone emulsion 30% (dry weight), macrogol 6000, sodium carmellose, polysorbate 80, vanilla flavor, bergamot flavor.

* obtained from pork pancreas

Dosage and administration of

The dose of Mezim® 20000 is set individually depending on the disease and the severity of symptoms.

Unless otherwise indicated, adults should take 1-2 tablets of Mezim® 20000 with meals. The drug is taken orally without breaking or chewing the tablet (the effectiveness of the Mezim® 20000 preparation may decrease with chewing and pancreatic enzymes upon release can irritate the oral mucosa), washed down with a sufficient amount of liquid (for example, a glass of water).

The daily dose of pancreatic enzymes corresponding to 15000-20000 PIECES of lipase / kg of body weight is not recommended to be exceeded.

Increasing the dose should be carried out only under the supervision of a doctor, while focusing on the symptoms (for example, a decrease in steatorrhea and abdominal pain).

The duration of treatment is determined by the doctor and can vary from several days (with digestive disorders due to errors in diet) to several months and even years (if necessary, constant replacement therapy).

In children, the dosage is determined by the doctor.

Dose for children and adults with cystic fibrosis

In patients with cystic fibrosis, the dose should be selected taking into account the severity of the symptoms of the disease, results of control of steatorrhea and maintenance of an adequate nutritional status (see section "Special instructions").

Dose should not exceed 10,000 units of lipase / kg body weight per day.

If, after treatment, improvement does not occur or the symptoms worsen, or new symptoms appear, consult a doctor.

Use the drug only according to the indications, the method of use and at the doses indicated in the instructions.

Side effects

Possible side effects are listed below in descending incidence: very often (? 1/10), often (> 1/100, <1/10), infrequently (> 1/1000, <1/100), rarely (> 1/10000, <1/1000), very rarely (<1/10000), frequency not established (according to available data it is impossible to estimate).

Immune system disorders

Very rare: immediate allergic reactions (such as skin rash, urticaria, sneezing, lacrimation, bronchospasm, dyspnea), gastrointestinal hypersensitivity.

Disorders of the gastrointestinal tract

Very rare: diarrhea, abdominal discomfort, abdominal pain, nausea, vomiting, stricture formation in the ileocecal and ascending parts of the colon in patients with cystic fibrosis with high doses of pancreatin.

Genitourinary disorders

Frequency unknown: hyperuricosuria (see Special Instructions).

If you have any side effects that are indicated in the instructions or are aggravated, or you notice any other side effects that are not listed in the instructions, inform your doctor.

Drug interaction

It is possible to reduce the absorption of folic acid while it is used with pancreatin preparations. The effect of hypoglycemic agents for oral administration (such as acarbose, miglitol) may decrease with the simultaneous use of digestive enzymes with enzymes that break down carbohydrates (for example, amylase) with drugs.

If you are using the above or other medications (including over-the-counter), consult your doctor before using Mezim® 20000.

Overdose

Symptoms: hyperuricosuria and hyperuricemia (especially in patients with cystic fibrosis, receiving high doses of enzyme preparations).

Treatment: symptomatic therapy, withdrawal of the drug.

Storage conditions

Keep out of the reach and sight of children at temperatures not exceeding 25 РC.

Shelf life

3 years.

Deystvuyushtee substance

Pancreatin

dosage form

tablets

Possible product names

Mezim 20,000 tablets coated solution-solution 20 pcs.

Berlin-Chemie AG, Germany

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