Otrivin spray nasal dosage. 0.05% bottle 10ml for children

Release form, composition and packaging

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Dosed nasal spray (for children) 0.05% in the form of a clear, colorless solution, practically odorless.

1 ml

xylometazoline hydrochloride 0.5 mg

sodium dihydrogen phosphate dihydrate - 5 mg, sodium hydrogen phosphate dodecahydrate - 1.7 mg, disodium edetate - 0.5 mg, benzalkonium chloride 50% solution - 0.1 mg (in terms of benzalkonium chloride - 0.05 mg), sorbitol 70% - 20 mg, hypromellose 4 thous. - 5 mg, sodium chloride - 4 mg, water - up to 1 ml.

10 ml - bottles made of high density polyethylene (1) with a pump dispensing device, a tip and a protective cap made of polyethylene - cardboard packs

pharmachologic effect

A vasoconstrictor drug for topical use in ENT practice (decongestant). Xylometazoline has an alpha-adrenomimetic effect. It causes narrowing of the blood vessels of the nasal mucosa, eliminating edema and hyperemia of the nasopharyngeal mucosa. Facilitates nasal breathing with rhinitis. Otrivin® is well tolerated by patients with sensitive mucous membranes its effect does not prevent mucus separation. The drug has a balanced pH value characteristic of the nasal cavity. The preparation contains inactive components - sorbitol and hypromellose, which are moisturizers, which helps to reduce the symptoms of irritation and dryness of the nasal mucosa that occur with prolonged use of xylometazoline. In therapeutic concentrations, the drug does not irritate the mucous membrane, does not cause hyperemia.The effect occurs 2 minutes after application and lasts for 12 hours. In vitro studies have shown that xylometazoline in humans suppresses the infectious activity of the rhinovirus that causes the cold".

Pharmacokinetics

When applied topically in recommended doses, it is practically not absorbed, plasma concentrations are below the detection limit.

Indications for use

- acute respiratory diseases with symptoms of rhinitis

- acute allergic rhinitis

- hay fever

- sinusitis

- eustachitis

- otitis media (to reduce swelling of the nasopharyngeal mucosa)

- preparation of the patient for diagnostic manipulations in the nasal passages.

Contraindications for use

- hypersensitivity to xylometazoline and other components of the drug

- arterial hypertension

- tachycardia

- severe atherosclerosis

- glaucoma

- dry rhinitis or atrophic rhinitis

- hyperthyroidism

- condition after transsphenoidal hypophysectomy

- Surgical interventions on the meninges (in history)

- children under 2 years old.

With care: diabetes mellitus

pheochromocytoma

cardiovascular diseases (including ischemic heart disease, angina pectoris)

hyperplasia of the prostate

with increased sensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.

Dosage regimen

Children from 2 to 5 years old: 1 injection in each nasal passage 1-3 times / day.

Children from 6 to 11 years old: 1-2 injections into each nasal passage 2-3 times / day.

Should not be used more than 3 times / day.

It is recommended to apply one last time just before bedtime.

The drug should be used under adult supervision.

Overdose

Symptoms: Xylometazoline, when applied topically in an excessive dose or when taken accidentally, can cause severe dizziness, increased sweating, a sharp drop in body temperature, headache, bradycardia, increased blood pressure, respiratory depression, coma and convulsions.

Following an increase in blood pressure, a sharp decrease can be observed.

Treatment: Appropriate supportive measures should be taken in case of any suspicion of an overdose, in some cases, immediate symptomatic treatment is indicated under medical supervision.

These measures should include monitoring the patient for several hours.

In case of severe poisoning with a stop

Name ENG

OTRIVIN

Clinical and pharmacological group

A vasoconstrictor drug for local use in ENT practice

ATX code

Xylometazoline

Dosage

0.05% x 10ml

Structure

1 ml: - xylometazoline hydrochloride 500 μg.

Excipients: sodium dihydrogen phosphate dihydrate - 5 mg, sodium hydrogen phosphate dodecahydrate - 1.7 mg, disodium edetate - 500 μg, benzalkonium chloride (in the form of a 50% solution) - 100 μg, sorbitol 70% - 20 mg, hypromellose-4 thousand - 5 mg, sodium chloride - 4 mg, purified water - up to 1 ml.

Indications

acute respiratory diseases with symptoms of rhinitis (runny nose)

acute allergic rhinitis

hay fever

sinusitis

eustachitis

otitis media (to reduce swelling of the nasopharyngeal mucosa)

preparation of the patient for diagnostic manipulations in the nasal passages

INN / Active ingredient

Xylometazoline

Contraindications

arterial hypertension

tachycardia

severe atherosclerosis

glaucoma

atrophic rhinitis

hyperthyroidism

surgical interventions on the meninges (in history)

hypersensitivity to the components of the drug Otrivin.,

It is used with caution in patients with diabetes mellitus, cardiovascular diseases, with hypersensitivity to adrenergic drugs, accompanied by symptoms of insomnia, dizziness, cardiac arrhythmia, tremor, increased blood pressure.

Storage conditions and periods

At a temperature not higher than 30 degrees.

Expiration date: 3 years

Specifications

Category

Runny nose

Scope of the drug

Ear, Throat, Nose

Release form

Spray

Manufacturer country

Switzerland

Package quantity, pcs

one

Scope of application

Virology

Minimum age from

6 years

Way of introduction

Through the respiratory tract

Vacation conditions

Without recipe

Volume, ml.

10 ml

Brand name

Otrivin

The amount of the dosage form in the primary package

10 ml

Primary packaging type

Polyethylene bottle with a dosing device

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Decongestant - alpha adrenergic agonist

Anatomical and therapeutic characteristics

R01AA07 Xylometazoline

Dosage form

Dosed nasal spray [for children]

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

xylometazoline hydrochloride 500 mcg

The target audience

Children

Package weight, g

35

Mode of application

:

Otrivin nasal spray is prescribed for adults and children over 6 years of age, 1 injection on each nasal day (if necessary, you can use it again), usually 3-4 injections per day are enough. < br> Otrivin nasal spray dosed (for children) 0.05% is prescribed for breastfeeding children and children under the age of 6 years, 1 injection into each nasal passage 1-2 times / day, should not be used more than 3 times / day

children over 6 years old are prescribed 2-3 injections into each nasal passage 3-4 times / day. < br> Duration of use - no more than 10 days in a row.

Information on technical characteristics, delivery set, country of manufacture "