nystatin | Nystatin ointment 100000 units / g 30 g

Latin name

Nystatin ointment

Release form

Ointment for external use

Pharmacological action

Nystatin is a polyene antifungal antibiotic that is highly active against yeast-like fungi of the genus Candida. It has a fungicidal effect. In the structure of the antibiotic, there are a large number of double bonds with high tropism for sterol structures of the cytoplasmic membrane of fungi, which contributes to the incorporation of the drug molecule into the cell membrane and the formation of a large number of channels through which uncontrolled transport of electrolytes occurs. An increase in osmolarity inside the cell leads to its death.

Contraindications

Hypersensitivity, impaired liver function, pancreatitis, peptic ulcer of the stomach and duodenum, pregnancy.

Composition

Active ingredient: nystatin 100000 IU

Excipients: lanolin anhydrous petroleum jelly.

Dosage and administration

Locally, apply the ointment in a thin layer to the affected areas of the skin and mucous membranes 1-2 times per day, daily for 7-10 days. Can be combined with oral administration.

Side effects

Nausea, vomiting, diarrhea, sometimes fever, chills. There is a risk of the spread of resistant forms of fungi (requires discontinuation of the drug).

Drug interaction

With the simultaneous use of nystatin with clotrimazole, the activity of the latter decreases.

Storage conditions

In a dry, dark place, at a temperature not exceeding 5 РC.

Term hodnosty

3 years

Deystvuyuschee substances

nystatin

Pharmacy terms

Prescription

Dosage form

ointment