Nystatin vaginal suppositories 500 000 ED, No. 10

• vaginal candidiasis;

• prevention of fungal complications with local antimicrobial therapy.

Vaginal suppositories are inserted into the vagina after hygiene procedures, 1 suppository 2 times / day (morning and evening). The course of treatment is 10-14 days.

Vaginal suppositories are yellow, torpedo-shaped.

1 supp.

nystatin 500,000 units

Excipients: paraoxybenzoic acid propyl ester, food citric acid, Witepsol N-15, Witepsol W-35.

• liver dysfunction;

• pancreatitis;

• peptic ulcer of the stomach and duodenum;

• pregnancy;

• hypersensitivity to the components of the drug.

pharmachologic effect

Antifungal drug from the polyene group. By binding to sterols in the cell membrane of fungi, it disrupts its permeability, which leads to the release of the main components of the cell. Has fungistatic effect.

Active against yeast-like fungi of the genus Candida.

Side effect

From the digestive system: when taking the drug inside and using rectal suppositories, nausea, vomiting, diarrhea are possible.

Allergic reactions: itching, chills, fever.

Others: the risk of spreading resistant forms of fungi is possible, which requires discontinuation of the drug.

Application during pregnancy and lactation

Nystatin is contraindicated in pregnancy.

Application for violations of liver function

Contraindicated in liver dysfunction.

special instructions

With the development of adverse reactions, the dose should be reduced or the drug should be discontinued.

During menstruation, you should not interrupt the treatment with vaginal suppositories. In case of fungal diseases of the vagina, simultaneous treatment of the sexual partner is recommended. During the period of treatment, sexual intercourse should be avoided.

Overdose

Currently, no cases of overdose of the drug Nystatin have been reported.

Drug interactions

With the simultaneous use of nystatin and clotrimazole, the activity of the latter decreases.