Novocaine 2% 20ml

DESCRIPTION

Novocaine - solution for injection is used as a local anesthetic for animals.

COMPOSITION

100 ml of solution contain novocaine (procaine hydrochloride) 0.5 g; excipients: solution of hydrochloric acid 0.1M; water for injections.

PHARMACOLOGICAL PROPERTIES

Novocaine belongs to the group of local anesthetic drugs.

Novocaine blocks sodium channels, displaces calcium from receptors located on the inner surface of the membrane and, thus, prevents the generation of impulses at the endings of sensory nerves and the conduction of impulses along nerve fibers. Suppresses conduction of not only painful, but also impulses of a different modality. When administered intravenously, it has a general effect on the animal body, reduces the formation of acetylcholine and lowers the excitability of peripheral cholin-reactive systems, has a blocking effect on the autonomic ganglia, reduces spasms of smooth muscles, lowers the excitability of the heart muscle and the excitability of the motor areas of the cerebral cortex.

In toxic doses, it causes excitement, then paralysis of the central nervous system. It rapidly hydrolyzes in the body, forming para-aminobenzoic acid and diethidaminoethanol, which are pharmacologically active substances. After administration, the drug acts quickly and for a short time.

According to the degree of impact on the body, Novocaine 0.5% and 2% solution for injections are classified as low-hazard substances (hazard class 4), novocaine powder is highly hazardous (hazard class 2) according to GOST 12.1.007-76.

DOSAGE AND APPLICATION

Novocaine 0.5% and 2% solution for injection is used, if necessary, diluted with sterile saline to the desired concentration, for infiltration anesthesia in the form of 0.25% -0.5% solution; for anesthesia according to A.V. Vishnevsky (tight creeping infiltration) - 0.125% -0.25%; for conduction and spinal anesthesia 1% -2%.

In ophthalmology, a 0.5% solution of novocaine is used for keratitis, keratoconjunctivitis, periodic inflammation of the eyes in horses (infraorbital blockade).

In obstetric and gynecological practice, novocaine solutions are prescribed for endometritis, metritis, prolapse of the uterus and vagina, retention of the placenta in cows and goats (perirenal blockade according to A.V. Vishnevsky), with serous-catarrhal mastitis (blockade of udder nerves according to B.A. Bashkirov or D.D.Logvinov) in the form of a 0.25% -0.5% solution.

Novocaine 0.5% and 2% solution for injection are also used as a solvent for drugs.

Solutions of novocaine are used subcutaneously, intramuscularly.

The concentration of the solution, the dose, the method of administration depend on the nature of the surgical intervention or the course of the disease, the type, weight, age of the animal and its condition.

When carrying out local anesthesia, the toxicity of novocaine is the higher, the more concentrated the applied solution is. In this regard, with an increase in the concentration of the solution, the total dose is reduced or the standard solution of the drug is diluted to a lower concentration (0.125% -0.25%) with sterile isotonic sodium chloride 0.9% solution or Ringer-Locke's solution. These dilutions are prepared immediately prior to use.

Maximum doses of novocaine in ml per animal:

Animal species 2% solution of novocaine

Horses 125

Cattle one hundred

Small cattle 37

Pigs 37

Dogs 25

Re-introduction of novocaine solutions is performed according to indications, but not earlier than 24 hours after the first injection.

SPECIAL INSTRUCTIONS

Products of animal origin obtained from animals after the use of Novocaine 0.5% and 2% solution for injection can be used without restrictions.

CONTRAINDICATIONS

Contraindications to the use of Novocaine 0.5% and 2% solution for injection have not been established, with the exception of individual hypersensitivity to procaine.

SIDE EFFECTS

In case of an overdose, novocaine causes excitement, then - paralysis of the central nervous system. In these cases, drugs are used to stimulate the work of the cardiovascular and respiratory systems, infusion solutions.

In recommended doses, it does not cause side effects and complications in animals.

SHELF LIFE AND STORAGE

Store the drug in the manufacturer's closed packaging, in a dry place protected from direct sunlight, separately from food and feed, at a temperature from 0 В° C to 25 В° C.

The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture. It is prohibited to use Novocaine 0.5% and 2% solution for injection after the expiration date. Should be stored out of the reach of children.

Dispose of unused product in accordance with legal requirements.

PACKAGING

Glass bottle 20 ml.

Specifications

KolVUP

40

Manufacturer

Mosagrogen

Temperature regime

from 0 to +25

Teaser

used in animals as a local anesthetic and for blockades