Normase syrup 667 mg / ml fl. 200ml

Special Price $12.61 Regular Price $21.00
In stock
SKU
OTC10202551
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Category

Laxatives

Scope of the medicinal product

Gastrointestinal tract

Release form

Syrup

Manufacturer country

Italy

Package quantity, pcs

one

Description

Release form, composition and packaging

The syrup is transparent, colorless or light yellow with a brownish shade.

100 g

lactulose 66.7 g

citric acid - 0.05 g, creamy flavor (No. 7 bis) - 0.06 g, purified water - up to 100 ml.

Flavor composition: propylene glycol, dihydrocoumarin, vanillin.

200 ml - dark glass bottles (1) complete with a measuring cup - cardboard packs.

pharmachologic effect

Laxative.

It has a hyperosmotic, hypoammoniemic, laxative effect, stimulates intestinal motility, improves the absorption of phosphates and calcium salts.

Under the influence of the drug, the flora of the colon changes (an increase in the number of lactobacilli), which leads to an increase in acidity in the lumen of the colon and stimulates peristalsis.

Along with this, the volume increases and the feces soften.

As a result, the drug has a laxative effect without directly affecting the mucous membrane and smooth muscles of the colon.

Under the action of the drug, ammonia passes from the blood into the intestine, while the formation of nitrogen-containing toxic substances in its proximal section decreases and, accordingly, their absorption into the vena cava system.

The action can occur quickly or be delayed - after 24-48 hours.

Has the ability to inhibit the growth of Salmonella in the colon.

Does not decrease absorption of vitamins and is not addictive.

Pharmacokinetics

The absorption is low.

It is excreted through the intestines unchanged, 3% is excreted by the kidneys.

Indications for use

- chronic constipation

- regulation of stool in case of hemorrhoids, the need for surgery on the colon and in the anus, in the postoperative period

- hepatic precoma and coma

- hepatic encephalopathy

- hyperammonemia

- dysbiosis

- salmonellosis (except for generalized forms).

Contraindications for use

- intolerance to galactose or fructose

- galactosemia

- intestinal obstruction

- rectal bleeding (not hemorrhoidal)

- colostomy, ileostomy

- suspicion of appendicitis

- hypersensitivity to drug components.

The drug should be used with caution in diabetes mellitus.

Dosage regimen

The drug should be taken orally after meals.

For constipation, adults in the first 3 days are prescribed 15-40 ml / day, then 10-25 ml / day.

Children over 6 years old are prescribed 15 ml / day for the first 3 days, then 10 ml / day, at the age of 1-6 years - 5-10 ml / day, at the age of up to 1 year - 5 ml / day.

The duration of treatment is from 4 weeks to 3-4 months.

In hepatic coma, precoma, encephalopathy and hyperammonemia, the initial dose is 30-60 ml 3 times / day.

Then the dose is selected so that the soft stool is 2-3 times / day.

Treatment can last up to 3 months or more.

In the postoperative period, adults are prescribed 10-30 ml 3 times / day, children over 1 year old - 5-10 ml 2-3 times / day, under 1 year old - 5 ml 2-3 times / day.

The drug is prescribed 18-24 hours after surgery for 3-5 days.

Overdose

Data on drug overdose are not provided to Normase.

Side effect

From the digestive system: flatulence, nausea, diarrhea.

When using the drug in high doses for a long time in the treatment of hepatic encephalopathy due to diarrhea, the development of disorders of water and electrolyte metabolism is possible.

Drug interactions

With the simultaneous use of antibiotics and antacids, the effectiveness of lactulose is reduced.

Lactulose alters the pH-dependent release of enteric drugs.

It is not recommended to take lactulose within 2 hours after taking other medicines.

Application during pregnancy and lactation

Lactulose is safe when used during pregnancy and lactation (breastfeeding).

Special instructions

Name ENG

NORMASE

Clinical and pharmacological group

A laxative drug with osmotic properties.

Hypoammonic remedy

ATX code

Lactulose

Dosage

667mg / ml x 200ml

Structure

100 ml of syrup contains: active substance: lactulose solution (in terms of lactulose) 66.7 mg

excipients: citric acid

purified water

cream flavoring No. 7 bis (propylene glycol, dihydrocoumarin, vanillin).

Indications

chronic constipation

regulation of stool in case of hemorrhoids, the need for surgery on the colon and in the anus, in the postoperative period

hepatic precoma and coma, hepatic encephalopathy, hyperammonemia

dysbacteriosis, salmonellosis (except for generalized forms)

putrid dyspepsia syndrome in young children as a result of food poisoning.

Storage conditions and periods

At a temperature of 15-25 degrees (do not freeze).

Expiration date: 3 years

Contraindications

hypersensitivity

intolerance to galactose or fructose

galactosemia

intestinal obstruction

rectal bleeding, colo-, ileostomy

suspicion of appendicitis.

With care: diabetes mellitus.

INN / Active ingredient

lactulose

Specifications

Category

Laxatives

Scope of the medicinal product

Gastrointestinal tract

Release form

Syrup

Manufacturer country

Italy

Package quantity, pcs

one

Minimum age from

6 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

L. Molteni & C. dei Fratelli Alliti Societa

Components

measuring glass

The amount of the dosage form in the primary package

200 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Laxative

Anatomical and therapeutic characteristics

A06AD11 Lactulose

Dosage form

Syrup

The target audience

Children

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

lactulose 66.7 g

Package weight, g

315

Mode of application

:

For constipation, adults in the first 3 days are prescribed 15-40 ml / day, then 10-25 ml / day. Children over 6 years old - in the first 3 days, 15 ml / day is prescribed, then 10 ml / day, at the age of 1-6 years - 5-10 ml / day, at the age of 1 year - 5 ml / day. The duration of treatment is from 4 weeks to 3-4 months. < br> < br> With hepatic coma, precoma, encephalopathy and hyperammonemia, the initial dose is 30-60 ml 3 times / day. Then the dose is selected so that the stool is soft 2-3 times a day. Treatment can last up to 3 months or more. < br> < br> In the postoperative period, adults are prescribed 10-30 ml 3 times a day, children over 1 year old - 5-10 ml 2-3 times a day, up to 1 year - 5 ml 2-3 times a day. The drug is prescribed 18-24 hours after surgery for 3-5 days.

Information on technical characteristics, delivery set, country of manufacture

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