norfloxacin | Norbactin tablets 400 mg, 10 pcs.
Special Price
$16.49
Regular Price
$25.00
In stock
SKU
BID494285
Release form
Tablets
Tablets
Release form
Tablets
Pharmacological action
NORBACTIN is an antibacterial agent from the group of fluoroquinolones. It has a bactericidal effect. It acts on the bacterial enzyme DNA gyrase, which ensures supercoiling and, thus, the stability of bacterial DNA. Destabilization of the DNA chain leads to the death of bacteria. It has a wide spectrum of antibacterial action.
Indications
Bacterial infections of the urinary tract (pyelonephritis, cystitis, urethritis), genital organs (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea. Prevention of infections in patients with granulocytopenia, diarrhea of travelers.
Contraindications
Contraindicated in patients with anamnestic indications of hypersensitivity to norfloxacin or any other chemical analogue. It should not be used in patients with severe renal failure (creatinine clearance less than 10 ml / min / 1.73 m2) and pregnant.
Special instructions
If you need to prescribe the drug Norbactin® during lactation, you should decide whether to stop breastfeeding.
During treatment with the drug, patients should receive a sufficient amount of fluid (under the control of diuresis).
An increase in prothrombin index was observed during norfloxacin therapy.
During surgery, the condition of the blood coagulation system should be monitored.
During treatment with Norbactin®, exposure to direct sunlight should be avoided.
When pain appears in the tendons or at the first signs of tenosynovitis, it is recommended to cancel the drug.
Influence on the ability to drive vehicles and control mechanisms. Due to the possible occurrence of dizziness in patients, those taking Norbactin® should be careful when driving a car and engaging in other potentially dangerous activities that require increased attention and speed of psychomotor reactions (especially with the simultaneous use of alcohol).
Composition
1 tablet contains:
Active ingredient: norfloxacin 400 mg
Excipients: MCC croscarmellose sodium sodium lauryl sulfate starch corn silicon dioxide colloidal magnesium stearate talc peeled shell: hypromellose macrogol 400 talc purified titanium dioxide purified water (lost during the manufacturing process)
Dosage and Administration
Acute urinary tract infections - 400 mg twice daily for 7-10 days.
Acute uncomplicated cystitis - 400 mg twice daily for 3 days.
Recurrent or chronic urinary tract infections with exacerbations - 400 mg twice a day for 4 weeks, then, if necessary, 400 mg per day for up to 12 weeks.
There is evidence of a significant decrease in the frequency of relapse of urinary tract infections in women with frequent recurrent infections with prophylactic administration of 200 mg of Norbactin once after sexual intercourse.
Chemoprophylaxis in urological interventions, operations and in postoperative infections - 400 mg twice a day before and after surgery, as needed.
Acute uncomplicated gonococcal infections - 800 mg once.
Bacterial intestinal infections - 400 mg twice daily for 5 days.
Prevention of travelers diarrhea - 400 mg once a day (no more than 21 days). The widespread use of antibacterial agents for the prevention of diarrhea is not recommended, they can be used in high-risk areas, in the presence of aggravating factors (hypochlorhydria, the use of antacids and secretion inhibitors, dysammaglobulinemia) and a high risk of complications due to dehydration in somatic diseases, taking diuretics, cardiac glycosides.
For best effectiveness and tolerability, Norbactin should be taken one hour before or two hours after a meal. It can not be taken with antacids. Patients are advised to drink enough fluid to prevent crystalluria.
Patients with renal failure (creatinine clearance from 10 to 30 ml / min / 1.73 m2) - 400 mg once a day.
Side effects of the digestive system: anorexia, bitterness in the mouth, nausea, vomiting, abdominal pain, diarrhea, pseudomembranous enterocolitis (with prolonged use), increased activity of hepatic transaminases.
From the urinary system: crystalluria, glomerulonephritis, dysuria, polyuria, albuminuria, urethral bleeding, hypercreatininemia.
From the nervous system: headache, dizziness, insomnia, hallucinations.
From the cardiovascular system: tachycardia, arrhythmias, decreased blood pressure, fainting, vasculitis.
Allergic reactions: pruritus, urticaria, edema, Stevens-Johnson syndrome.
From the musculoskeletal system: arthralgia, tendonitis, tendon ruptures.
From the hemopoietic organs: leukopenia, eosinophilia, decreased hematocrit.
Other: candidiasis.
Drug administration
Simultaneous administration of antacids containing aluminum or magnesium hydroxide, as well as drugs that contain norexulfate, zinc, and zinc not less than 4 hours).
Reduces clearance of theophylline by 25%, therefore, with simultaneous use, the dose of theophylline should be reduced.
The simultaneous administration of norfloxacin with drugs with the potential ability to lower blood pressure can cause a sharp decrease in blood pressure. In this regard, in such cases, as well as with the simultaneous administration of barbiturate-containing, anesthetics, heart rate, blood pressure, ECG parameters should be monitored.
Concomitant use with drugs that lower the seizure threshold may lead to the development of epileptiform seizures.
Increases the concentration of indirect anticoagulants, cyclosporin (mutually) in serum.
Reduces the effect of nitrofurans.
Overdose
Symptoms (3 g in 45 min): dizziness, nausea, vomiting, drowsiness, cold sweat, puffy face without changes in basic hemodynamic parameters.
Treatment: gastric lavage, adequate hydration therapy with forced diuresis. An examination and observation in a hospital is required for several days.
There is no specific antidote.
Storage conditions
In a dry place, at a temperature not exceeding 25 РC.
Term hodnosty
3 years
active substance
norfloxacin
from
pharmacies Prescription
lekarstvennaja form
tablets
Prescribing
Adults as prescribed by a doctor
Indications
Indications
From inflammation of the female genital organs s, from an intestinal infection, from pharyngitis, cystitis, from urinary tract infections, prostatitis, urethritis from, from diarrhea
Ranbaksi Laboratoriz Limited, India
Tablets
Pharmacological action
NORBACTIN is an antibacterial agent from the group of fluoroquinolones. It has a bactericidal effect. It acts on the bacterial enzyme DNA gyrase, which ensures supercoiling and, thus, the stability of bacterial DNA. Destabilization of the DNA chain leads to the death of bacteria. It has a wide spectrum of antibacterial action.
Indications
Bacterial infections of the urinary tract (pyelonephritis, cystitis, urethritis), genital organs (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea. Prevention of infections in patients with granulocytopenia, diarrhea of travelers.
Contraindications
Contraindicated in patients with anamnestic indications of hypersensitivity to norfloxacin or any other chemical analogue. It should not be used in patients with severe renal failure (creatinine clearance less than 10 ml / min / 1.73 m2) and pregnant.
Special instructions
If you need to prescribe the drug Norbactin® during lactation, you should decide whether to stop breastfeeding.
During treatment with the drug, patients should receive a sufficient amount of fluid (under the control of diuresis).
An increase in prothrombin index was observed during norfloxacin therapy.
During surgery, the condition of the blood coagulation system should be monitored.
During treatment with Norbactin®, exposure to direct sunlight should be avoided.
When pain appears in the tendons or at the first signs of tenosynovitis, it is recommended to cancel the drug.
Influence on the ability to drive vehicles and control mechanisms. Due to the possible occurrence of dizziness in patients, those taking Norbactin® should be careful when driving a car and engaging in other potentially dangerous activities that require increased attention and speed of psychomotor reactions (especially with the simultaneous use of alcohol).
Composition
1 tablet contains:
Active ingredient: norfloxacin 400 mg
Excipients: MCC croscarmellose sodium sodium lauryl sulfate starch corn silicon dioxide colloidal magnesium stearate talc peeled shell: hypromellose macrogol 400 talc purified titanium dioxide purified water (lost during the manufacturing process)
Dosage and Administration
Acute urinary tract infections - 400 mg twice daily for 7-10 days.
Acute uncomplicated cystitis - 400 mg twice daily for 3 days.
Recurrent or chronic urinary tract infections with exacerbations - 400 mg twice a day for 4 weeks, then, if necessary, 400 mg per day for up to 12 weeks.
There is evidence of a significant decrease in the frequency of relapse of urinary tract infections in women with frequent recurrent infections with prophylactic administration of 200 mg of Norbactin once after sexual intercourse.
Chemoprophylaxis in urological interventions, operations and in postoperative infections - 400 mg twice a day before and after surgery, as needed.
Acute uncomplicated gonococcal infections - 800 mg once.
Bacterial intestinal infections - 400 mg twice daily for 5 days.
Prevention of travelers diarrhea - 400 mg once a day (no more than 21 days). The widespread use of antibacterial agents for the prevention of diarrhea is not recommended, they can be used in high-risk areas, in the presence of aggravating factors (hypochlorhydria, the use of antacids and secretion inhibitors, dysammaglobulinemia) and a high risk of complications due to dehydration in somatic diseases, taking diuretics, cardiac glycosides.
For best effectiveness and tolerability, Norbactin should be taken one hour before or two hours after a meal. It can not be taken with antacids. Patients are advised to drink enough fluid to prevent crystalluria.
Patients with renal failure (creatinine clearance from 10 to 30 ml / min / 1.73 m2) - 400 mg once a day.
Side effects of the digestive system: anorexia, bitterness in the mouth, nausea, vomiting, abdominal pain, diarrhea, pseudomembranous enterocolitis (with prolonged use), increased activity of hepatic transaminases.
From the urinary system: crystalluria, glomerulonephritis, dysuria, polyuria, albuminuria, urethral bleeding, hypercreatininemia.
From the nervous system: headache, dizziness, insomnia, hallucinations.
From the cardiovascular system: tachycardia, arrhythmias, decreased blood pressure, fainting, vasculitis.
Allergic reactions: pruritus, urticaria, edema, Stevens-Johnson syndrome.
From the musculoskeletal system: arthralgia, tendonitis, tendon ruptures.
From the hemopoietic organs: leukopenia, eosinophilia, decreased hematocrit.
Other: candidiasis.
Drug administration
Simultaneous administration of antacids containing aluminum or magnesium hydroxide, as well as drugs that contain norexulfate, zinc, and zinc not less than 4 hours).
Reduces clearance of theophylline by 25%, therefore, with simultaneous use, the dose of theophylline should be reduced.
The simultaneous administration of norfloxacin with drugs with the potential ability to lower blood pressure can cause a sharp decrease in blood pressure. In this regard, in such cases, as well as with the simultaneous administration of barbiturate-containing, anesthetics, heart rate, blood pressure, ECG parameters should be monitored.
Concomitant use with drugs that lower the seizure threshold may lead to the development of epileptiform seizures.
Increases the concentration of indirect anticoagulants, cyclosporin (mutually) in serum.
Reduces the effect of nitrofurans.
Overdose
Symptoms (3 g in 45 min): dizziness, nausea, vomiting, drowsiness, cold sweat, puffy face without changes in basic hemodynamic parameters.
Treatment: gastric lavage, adequate hydration therapy with forced diuresis. An examination and observation in a hospital is required for several days.
There is no specific antidote.
Storage conditions
In a dry place, at a temperature not exceeding 25 РC.
Term hodnosty
3 years
active substance
norfloxacin
from
pharmacies Prescription
lekarstvennaja form
tablets
Prescribing
Adults as prescribed by a doctor
Indications
Indications
From inflammation of the female genital organs s, from an intestinal infection, from pharyngitis, cystitis, from urinary tract infections, prostatitis, urethritis from, from diarrhea
Ranbaksi Laboratoriz Limited, India
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