Nicotinic acid tablets 50mg, No. 50

Prevention and treatment of pellagra (PP avitaminosis); complex therapy of ischemic disorders of cerebral circulation, obliterating diseases of the vessels of the extremities (obliterating endarteritis, Raynaud's disease) and kidneys, complications of diabetes mellitus (diabetic polyneuropathy, microangiopathy); liver diseases (acute and chronic hepatitis), gastritis with low acidity, neuritis of the facial nerve, various intoxications (occupational, drug, alcoholic), long-term non-healing wounds and ulcers.

It is used as directed by a doctor.
Nicotinic acid tablets are taken orally after meals. As an antipellargic agent, nicotinic acid is prescribed for adults at 0.1 g 2-4 times a day (the highest daily dose is 0.5 g). Children are prescribed from 0.0125 to 0.05 g 2-3 times a day, depending on age. The course of treatment is 15-20 days.
Adults with ischemic disorders of cerebral circulation, vascular spasms of the extremities, gastritis with low acidity, neuritis of the facial nerve, wounds and ulcers are recommended to prescribe nicotinic acid in a single dose of 0.05-0.1 g, in a daily dose - up to 0.5 g. treatment - 1 month.

1 tablet contains:
Active ingredients: 0.05 g of nicotinic acid.
Excipients: glucose, stearic acid.

Hypersensitivity to the drug. Peptic ulcer and 12-duodenal ulcer (in the acute stage); severe arterial hypertension; gout; hyperuricemia, nephrolithiasis, liver cirrhosis, decompensated diabetes mellitus.
Pregnancy and the period of breastfeeding.

Trade name : Nicotinic acid

International non-proprietary name : Nicotinic acid

Chemical name : 3-pyridinecarboxylic acid

Dosage form : tablets

Composition
1 tablet contains:
Active ingredients: 0.05 g of nicotinic acid.
Excipients: glucose, stearic acid.

Description . The tablets are white.

Pharmacotherapeutic group . An agent that regulates metabolic processes. Vitamin preparation.

ATX code : [S10AD02].

Pharmacological properties .
Nicotinic acid is a specific antipellargic agent (vitamin PP). Improves carbohydrate metabolism, has a vasodilating effect, including on the vessels of the brain, has lipid-lowering activity. In large doses of 3-4 g per day, nicotinic acid reduces the content of triglycerides and low-density lipoproteins in the blood, reduces the ratio of cholesterol / phospholipids in low-density lipoproteins. Possesses detoxification properties.

Indications for use :
Prevention and treatment of pellagra (vitamin deficiency PP); complex therapy of ischemic disorders of cerebral circulation, obliterating diseases of the vessels of the extremities (obliterating endarteritis, Raynaud's disease) and kidneys, complications of diabetes mellitus (diabetic polyneuropathy, microangiopathy); liver diseases (acute and chronic hepatitis), gastritis with low acidity, neuritis of the facial nerve, various intoxications (occupational, drug, alcoholic), long-term non-healing wounds and ulcers.

Contraindications :
Hypersensitivity to the drug. Peptic ulcer and 12-duodenal ulcer (in the acute stage); severe arterial hypertension; gout; hyperuricemia, nephrolithiasis, liver cirrhosis, decompensated diabetes mellitus.
Pregnancy and the period of breastfeeding.

Special instructions
To prevent complications from the liver (with prolonged use in large doses), it is recommended to include in the diet foods rich in methionine (cottage cheese) or to use methionine, lipoic acid, Essentiale and other lipotropic agents. It should be used with caution in case of gastritis with high acidity, gastric ulcer and duodenal ulcer (in history). During treatment with nicotinic acid (especially in large doses), liver function should be carefully monitored.

Method of administration and dosage
It is used as directed by a physician.
Nicotinic acid tablets are taken orally after meals. As an antipellargic agent, nicotinic acid is prescribed for adults at 0.1 g 2-4 times a day (the highest daily dose is 0.5 g). Children are prescribed from 0.0125 to 0.05 g 2-3 times a day, depending on age. The course of treatment is 15-20 days.
For adults with ischemic disorders of cerebral circulation, vasospasm of the limbs, gastritis with low acidity, neuritis of the facial nerve, wounds and ulcers, nicotinic acid is recommended to be prescribed in a single dose of 0.05-0.1 g, in a daily dose - up to 0.5 g. treatment - 1 month.

Side effect
Allergic reactions, dizziness, facial flushing, a feeling of flushing to the head, paresthesia are possible. In this case, you should reduce the dose or discontinue the drug. With prolonged use of large doses of nicotinic acid, it is possible to develop fatty degeneration of the liver, hyperuricemia, an increase in the activity of hepatic transaminases and alkaline phosphatase, and a decrease in glucose tolerance.

Interaction with other medicinal products
It is necessary to consult a doctor if nicotinic acid will be used concomitantly with other medicinal products.

Release form
50 tablets in dark glass jars. 10 tablets in a blister strip packaging. Each can or 5 blisters are placed in a cardboard box.

Shelf life is
4 years. Do not use the drug after the expiration date.

Storage conditions
List B. Store at room temperature, in a dry, dark place. Keep out of the reach of children.

Dispensing from pharmacies
Without prescription.