Neuromultivit tablets p / o, No. 60

It is used in the complex therapy of the following neurological diseases:

• Polyneuropathies of various etiologies (diabetic, alcoholic, etc.)

• Intercostal neuralgia

• Trigeminal neuralgia

Radicular syndrome caused by degenerative changes in the spine

• Cervical syndrome

• Shoulder-scapular syndrome

• Lumbar syndrome

• Lumboishalgia

The tablets should be taken after meals, without chewing and with a small amount of liquid.
Assign 1 tablet 1-3 times a day.
The duration of the course is according to the doctor's recommendation.
Treatment with high doses of the drug for more than 4 weeks is not recommended.

One tablet contains:
active substances:
thiamine hydrochloride 100.00 mg;
pyridoxine hydrochloride 200.00 mg;
cyanocobalamin 0.20 mg;
excipients:
microcrystalline cellulose 80.0 mg, magnesium stearate 4.8 mg, povidone 15.0 mg;
shell: macrogol 6000 9.0 mg, titanium dioxide 11.25 mg, talc 30.0 mg, hypromellose 7.5 mg, methyl methacrylate and ethyl acrylate copolymer 1: 2 [dispersion 30%] 2.25 mg.

Hypersensitivity to the components of the drug.

Children's age (the effectiveness and safety of the drug have not been studied)

Trade name of the drug:

NeuromultivitЃ

Grouping name:

multivitamins

Dosage form:

Film-coated tablets

Composition:

One tablet contains:
active substances:
thiamine hydrochloride 100.00 mg;
pyridoxine hydrochloride 200.00 mg;
cyanocobalamin 0.20 mg;
excipients:
microcrystalline cellulose 80.0 mg, magnesium stearate 4.8 mg, povidone 15.0 mg;
shell: macrogol 6000 9.0 mg, titanium dioxide 11.25 mg, talc 30.0 mg, hypromellose 7.5 mg, methyl methacrylate and ethyl acrylate copolymer 1: 2 [dispersion 30%] 2.25 mg.

Description:

Round, biconvex tablets, white or almost white, film-coated. On a cross section from white to light pink interspersed from light pink to dark pink.

Pharmacotherapeutic group:

multivitamin remedy.

ATX code:

A11EA

pharmachologic effect

The pharmacological action is determined by the properties of the vitamins that make up the drug.

Thiamine (vitamin B1) in the human body, as a result of phosphorylation processes, is converted into cocarboxylase, which is a coenzyme of many enzymatic reactions. Thiamine plays an important role in carbohydrate, protein and fat metabolism. It actively participates in the processes of conducting nervous excitement in synapses. Pyridoxine (vitamin B6) is essential for the normal functioning of the central and peripheral nervous system. In phosphorylated form, it is a coenzyme in the metabolism of amino acids (decarboxylation, transamination, etc.). Acts as a coenzyme of the most important enzymes acting in nerve tissues. It participates in the biosynthesis of many neurotransmitters, such as dopamine, norepinephrine, adrenaline, histamine, and gamma-aminobutyric acid.

Cyanocobalamin (vitamin B12) is necessary for normal hematopoiesis and erythrocyte maturation, and also participates in a number of biochemical reactions that ensure the vital activity of the body - in the transfer of methyl groups, in the synthesis of nucleic acids, protein, in the exchange of amino acids, carbohydrates, lipids. It has a beneficial effect on the processes in the nervous system (synthesis of nucleic acids and the lipid composition of cerebrosides and phospholipids). The coenzyme forms of cyanocobalamin, methylcobalamin and adenosylcobalamin, are required for cell replication and growth.

Indications for use

It is used in the complex therapy of the following neurological diseases:

• Polyneuropathies of various etiologies (diabetic, alcoholic, etc.)

• Intercostal neuralgia

• Trigeminal neuralgia

Radicular syndrome caused by degenerative changes in the spine

• Cervical syndrome

• Shoulder-scapular syndrome

• Lumbar syndrome

• Lumboishalgia

Contraindications

Hypersensitivity to the components of the drug.

Children's age (the effectiveness and safety of the drug have not been studied).

Application during pregnancy and lactation

Due to the limited experience with the use of NEUROMULTIVIT, it is not recommended to prescribe it during pregnancy and breastfeeding.

Method of administration and dosage

The tablets should be taken after meals, without chewing and with a small amount of liquid.
Assign 1 tablet 1-3 times a day.
The duration of the course is according to the doctor's recommendation.
Treatment with high doses of the drug for more than 4 weeks is not recommended.

Side effect

NEUROMULTIVITIS is well tolerated by patients. In isolated cases, nausea, tachycardia, skin reactions in the form of itching and urticaria may occur.

Overdose

Clinical symptoms of an overdose of vitamins contained in Neuromultivitis can only be expected after taking extremely high doses for a very long time.
Vitamin B1 - there were no symptoms of overdose after oral administration.
Vitamin B6 - after taking more than 2 g per day, neuropathies with ataxia and impaired sensitivity, seizures with changes in the EEG and, in some cases, hypochromic anemia and seborrheic dermatitis are described.
Vitamin B12 - after parenteral administration (in rare cases and after ingestion), eczematous skin changes and acne were observed.
Treatment is symptomatic.

Interaction with other medicinal products

Pyridoxine reduces the antiparkinsonian efficacy of levodopa. Ethanol dramatically reduces the absorption of thiamine. While taking Neuromultivit, it is not recommended to take multivitamin complexes that include B vitamins.

special instructions

Cyanocobalamin may mask symptoms of folate deficiency.

Influence on the ability to drive vehicles and mechanisms

Neuromultivitis does not affect the ability to drive vehicles and mechanisms.

Release form:

Film-coated tablets.
20 tablets in PVC / Al blister. 1 blister with instructions for use in a cardboard box.

Storage conditions

In a dry, dark place at a temperature not exceeding 25 ? C. Keep out of the reach of children.

Shelf life:

3 years.
Do not use after the expiration date.

Conditions of dispensing from pharmacies

On prescription.