Neomectin 1%, 100ml

DESCRIPTION

Neomectin 1% (Neomectin 1%) drug is prescribed to animals with a therapeutic and prophylactic purpose for arachno-entomoses and nematodes. In appearance, the drug is a clear, colorless or yellowish liquid.

COMPOSITION

Neomectin 1% as an active ingredient in 1 ml contains: ivermectin - 10 mg and excipients: ethyl alcohol, benzyl alcohol, water for injection, propylene glycol.

PHARMACOLOGICAL PROPERTIES

Neomectin 1% belongs to the group of antiparasitic drugs.

Ivermectin, which is part of the drug, a compound of the class of macrocyclic lactones, has a pronounced systemic antiparasitic effect on the larval and mature phases of the development of nematodes of the gastrointestinal tract and lungs, the larvae of subcutaneous, nasopharyngeal, gastric gadflies, lice, bloodsuckers and sarcoptoid ticks.

The main targets of ivermectin action are glutamate-sensitive chlorine channels, as well as gamma-aminobutyric acid receptors in nematodes, gadfly larvae, and ectoparasites. A change in the current of chlorine ions through the membranes of nerve and muscle cells disrupts the conduction of impulses, which leads to paralysis and death of parasites.

After parenteral administration of the drug, ivermectin is rapidly absorbed from the injection site and distributed in the organs and tissues of the animal, providing a long-term antiparasitic effect. It is excreted from the body with urine and bile, in lactating animals also with milk.

According to the degree of impact on the body, according to GOST 12.1.007-76, Neomectin 1% refers to moderately hazardous substances (hazard class 3). In recommended doses, the drug does not possess teratogenic, embryotoxic and mutagenic properties. It quickly collapses in the external environment. The drug is toxic to bees, as well as fish and other aquatic organisms.

PURPOSE

The drug is prescribed for animals with a therapeutic and prophylactic purpose for arachno-entomoses and nematodoses: cattle with strongilatosis, dictyocaulosis, trichocephalosis, strongyloidosis, telaziosis, sifunculatosis, hypodermatosis, psoroptosis and psoroptosis; sheep with dictyocaulosis, protostrongylosis, mulleriosis, haemonchosis, ostertagiasis, nematodyrosis, marshallagiosa, cooperiosis, habertiosis, esophagostomosis, bunostomosis, trichocephalosis, strongyloidosis, psoriasis, malophagosis; deer with dictyocaulosis, ostertagiasis, nematodyrosis, strongyloidiasis, trichocephalosis, edemagenosis, cephenomyosis and sarcoptic mange; pigs with trichocephalosis, ascariasis, metastrongylosis, esophagostomosis, strongyloidosis, stefanurosis, hematopinosis and sarcoptic mange.

DOSAGE AND APPLICATION

Neomectin 1% is administered to animals intramuscularly once in compliance with the rules of asepsis: pigs in the neck and inner surface of the thigh, ruminants - in the area of ​​the croup or neck in the following doses: cattle, sheep and deer - 1 ml of Neomectin 1% per 50 kg of weight animal (200 μg of ivermectin per 1 kg of body weight); pigs - 1 ml of Neomectin 1% per 3 3 kg of animal weight (3 00 μg of ivermectin per 1 kg of weight).

In severe cases of animal disease with sarcoptoidosis, treatment is carried out twice with an interval of 8-1O days.

If the volume of the injected solution is more than 1O ml, it should be administered to the animal in several places.

Treatment of animals with nematodes is carried out in the fall before being placed in a stall and in the spring before being taken to pasture, against gadfly infestations - immediately after the end of the flight of gadflies, against pathogens of arachno-entomoses - according to indications.

Each batch of the preparation is preliminarily tested on a small group (7-1 O heads) of animals. In the absence of complications, the entire livestock is processed within 3 days.

SPECIAL INSTRUCTIONS

In case of an overdose of the drug, animals may experience depression, tremor, increased salivation, refusal to feed, loose stools.

Neomectin 1% should not be used concurrently with other drugs containing macrocyclic lactones, due to the possible mutual enhancement of the toxic effect.

The peculiarities of the action of the drug during its first use and withdrawal were not revealed.

Violations of the drug use regimen should be avoided, as this can lead to a decrease in its effectiveness.

Slaughter for meat of ruminants and pigs is allowed no earlier than 28 days after the last application of Neomectin 1%. In the event of the forced slaughter of animals before the established deadline, the meat can be used as feed for fur animals.

CONTRAINDICATIONS

A contraindication to the use of the drug Neomectin 1% is an individual hypersensitivity to the components of the drug, including a history. It is not allowed to use the drug for patients with infectious diseases and malnourished animals.

Due to the release of ivermectin in milk, it is prohibited to use Neomectin 1% for dairy females, as well as for pregnant females whose milk will be used for food purposes, less than 28 days before lactation.

Do not use the drug for pregnant females less than 28 days before the expected birth.

SIDE EFFECTS

As a rule, side effects and complications are not observed when using the drug Neomectin 1% in accordance with this instruction. In some animals, increased salivation, increased frequency of bowel movements and urination, ataxia are possible. These symptoms usually go away spontaneously without the use of therapeutic agents. With increased individual sensitivity of the animal to the components of the drug and the appearance of side effects and complications, the use of the drug is discontinued and desensitizing therapy is carried out.

SHELF LIFE AND STORAGE

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 2 years from the date of production, after opening the bottle - 28 days. Store the drug in the manufacturer's closed packaging, protected from direct sunlight, separately from food and feed, at a temperature from 0 В° C to 25 В° C.

PACKAGING

Neomectin 1% is produced in 100 ml packaged in dark glass vials, sealed with rubber stoppers with aluminum caps. Vials with a capacity of 100 ml are packed individually in cardboard boxes. Each unit of consumer packaging is supplied with instructions for use.

Specifications

Bonus points

0

KolVUP

ten

Manufacturer

APICENNA

Temperature regime

from 0 to +25

Teaser

the drug is prescribed to animals with a therapeutic and prophylactic purpose for arachno-entomoses and nematodes