Description

Composition 1 ml contains: Active ingredient: oxymetazoline hydrochloride 0.1 mg

Pharmacological action Nazivin - alpha-adrenomimetic, vasoconstrictor

Pharmacodynamics Being a derivative of imidazoline, at low concentrations it mainly has α2-adrenomimetic effect, at high concentrations it also acts on α1-adrenergic receptors

It narrows the vessels at the site of application, reduces swelling of the nasal mucosa and upper respiratory tract.

With local nasal application in therapeutic concentrations, it does not irritate the mucous membrane, does not cause hyperemia

Studies of radiolabeled oxymetazoline have shown that this nasal rhinological agent does not have a systemic effect.

Indications acute respiratory diseases with symptoms of rhinitis

acute allergic rhinitis

exacerbation of vasomotor rhinitis

to facilitate the outflow of discharge from the paranasal sinuses with sinusitis, eustachitis, otitis media

to eliminate edema before diagnostic manipulations in the nasal passages

Contraindications Hypersensitivity, atrophic rhinitis, angle-closure glaucoma

Age up to 1 year - for Nazivin 0.025 and 0.05%

age up to 6 years - for Nazivin 0.05%

Side effects Sometimes - burning or dryness of the nasal mucosa, sneezing

rarely - a strong feeling of stuffiness" of the nose (reactive hyperemia)

very rarely - anxiety, insomnia, fatigue, headache, nausea

Repeated overdose with local nasal use sometimes leads to such systemic sympathomimetic effects as increased heart rate (tachycardia) and increased blood pressure

How to take, course of administration and dosage Adults and children over 6 years old - 1-2 drops in each nasal passage 2-3 times a day 0.05% solution

children: infants up to 4 weeks - 1 drop of 0.01% solution 2-3 times a day, from the 5th week of life and up to 1 year - 1-2 drops 2-3 times a day, from 1 year to 6 years - 1-2 drops 2-3 times a day 0.025% solution

To ensure the accuracy of dosing, the bottle of Nazivin 0.01% nasal drops has a graduated pipette with marks of the number of drops

The effectiveness of the following procedure has also been proven: depending on age, 1-2 drops of a 0.01% solution are applied to cotton wool and wiped the nasal passages

Overdose Symptoms (after a significant overdose or accidental ingestion): pupillary constriction, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, vascular insufficiency, arterial hypertension, respiratory distress, pulmonary edema, cardiac arrest

in addition, mental disorders may appear, as well as depression of the central nervous system, accompanied by drowsiness, a decrease in body temperature, bradycardia, arterial hypotension, respiratory arrest and the possible development of coma

Treatment: gastric lavage, taking activated charcoal and urgent medical attention

Special instructions Prolonged use of nasal decongestants may weaken their effect.

Abuse of these agents can cause mucosal atrophy and reactive hyperemia with rhinitis medicamentosa, as well as damage to the mucous epithelium and inhibition of epithelial activity.

Long-term use and overdose should be avoided

Release form Nasal drops Storage conditions In a dark place at a temperature not exceeding 25 ° C.

Shelf life 3 years Active ingredient Oxymetazoline Terms of dispensing from pharmacies Without prescription

Name ENG

NASIVIN

Clinical and pharmacological group

A vasoconstrictor drug for local use in ENT practice

ATX code

Oxymetazoline

Dosage

0.01% x 5ml

Structure

1 ml contains: Active ingredient: oxymetazoline hydrochloride 0.1 mg.

Indications

Acute rhinitis (including allergic), vasomotor rhinitis, paranasal sinusitis, eustachitis, otitis media.

Narrowing of the vessels of the mucous membrane for diagnostic purposes (under medical supervision).

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

Oxymetazoline

Contraindications

Hypersensitivity to drug components, atrophic rhinitis, angle-closure glaucoma.

Age up to 1 year for Nazivin® 0.025 and 0.05%

age up to 6 years for Nazivin® 0.05%.

Specifications

Category

Runny nose

Scope of the medicinal product

Ear, Throat, Nose

Release form

Drops

Manufacturer country

Germany

Package quantity, pcs

one

Scope of application

Virology

Way of introduction

Through the respiratory tract

Vacation conditions

Without recipe

Brand name

E. Merck

The amount of the dosage form in the primary package

5 ml

Primary packaging type

Bottle with pipette cap

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Decongestant - alpha adrenergic agonist

Anatomical and therapeutic characteristics

R01AA05 Oxymetazoline

Dosage form

Nasal drops

Dosage (volume) of the substance in the preparation

Nazivin 0.01% - Oxymetazoline hydrochloride 0.1 mg

Expiration date in days

1095

Package weight, g

twenty

Mode of application

:

Adults and children over 6 years old - 1-2 drops in each nasal passage 2-3 times a day 0.05% solution

children: infants up to 4 weeks - 1 drop of 0.01% solution 2-3 times a day, from the 5th week of life and up to 1 year - 1-2 drops 2-3 times a day, from 1 year to 6 years - 1-2 drops 2-3 times a day 0.025% solution < br> To ensure the accuracy of dosage, the bottle of Nazivin 0.01% nasal drops has a graduated pipette with marks of the number of drops < br> The following procedure has also been proven effective: depending on from age 1–2 drops of 0.01% solution are applied to cotton wool and wipe the nasal passages.

Information on technical characteristics, delivery set, country of manufacture "

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