Nasal nasal spray, dosed 10 ml (150 doses)

Release form, composition and packaging

Nasal spray 0.05% in the form of a clear, colorless solution, odorless.

100 ml

oxymetazoline hydrochloride 0.05 g

benzalkonium chloride - 0.02 g, macrogol 400 - 7.5 g, povidone - 0.4 g, propylene glycol - 7.5 g, sodium hydrogen phosphate dihydrate - 0.006 g, sodium dihydrogen phosphate dihydrate - 0.65 g, disodium edetate dihydrate - 0.1 g, hydrochloric acid conc.

- 0.003 g, purified water - 85.571 g.

15 ml - polyethylene bottles (1) with a spray device - cardboard packs.

30 ml - polyethylene bottles (1) with a spray device - cardboard packs.

pharmachologic effect

Oxymetazoline belongs to the group of topical alpha-adrenostimulants.

Has a vasoconstrictor effect.

When administered intranasally, it reduces the swelling of the mucous membrane of the upper respiratory tract, which leads to relief of nasal breathing and opening of the mouths of the paranasal sinuses and Eustachian tubes.

The effect of the drug manifests itself 10-15 minutes after application and lasts for 10-12 hours.

Indications for use

To facilitate nasal breathing when:

- colds and viral infections of the upper respiratory tract

- sinusitis and rhinitis of any etiology.

Contraindications for use

- hypersensitivity to the drug or its components

- atrophic rhinitis

- children under 6 years old

- pregnancy

- lactation period.

The drug should be used with caution in patients suffering from diseases of the cardiovascular system (arterial hypertension, ischemic heart disease, chronic heart failure, tachycardia, arrhythmias), impaired carbohydrate metabolism (diabetes mellitus), thyroid function (hyperthyroidism), pheochromocytoma, chronic renal failure, hyperplasia of the prostate (urinary retention) and angle-closure glaucoma, taking MAO inhibitors, tricyclic antidepressants.

Dosage regimen

Intranasally.

Adults and children over 12 years old - 2-3 injections into each nasal passage 2 times / day.

Children from 6 to 12 years old - 1 injection into each nasal passage 2 times / day.

Do not use the drug more than 2 times / day.

Duration of treatment: it is not recommended to use the drug for more than 3 days.

With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen.

If these symptoms appear, you should stop treatment and consult a doctor.

When injecting, do not tilt your head back and do not spray while lying down

Overdose

Prolonged or frequent use of the drug in the nasal cavity can cause nausea, increased blood pressure, tachycardia, and CNS depression.

Symptomatic treatment

Side effect

Sometimes burning or dryness of the nasal membranes, dryness in the mouth and throat, sneezing, increased volume of secretions from the nose.

In rare cases, after the effect of the drug has passed, a strong feeling of stuffiness" of the nose (reactive hyperemia).

Side effects due to the systemic effect of the drug: increased blood pressure, headache, dizziness, palpitations, increased anxiety, nausea, insomnia.

With prolonged use of the drug (more than 7 days), the following are possible: reactive hyperemia of the nasal mucosa, atrophy of the nasal mucosa, tachyphylaxis (a rapid decrease in the therapeutic effect with repeated use).

Drug interactions

With simultaneous use with MAO inhibitors (including a period within 14 days after their cancellation) and tricyclic antidepressants, an increase in blood pressure may be observed.

The drug slows down the absorption of local anesthetic drugs, lengthens their effect.

The co-administration of other vasoconstrictor drugs increases the risk of side effects.

Pregnancy and

Name ENG

NAZOL

Clinical and pharmacological group

A vasoconstrictor drug for local use in ENT practice

ATX code

Oxymetazoline

Dosage

0.025mg / dose x 10ml

Structure

1 ml: - oxymetazoline hydrochloride 500 μg.

Excipients: benzalkonium chloride (50% solution), benzyl alcohol, disodium edetate, macrogol 400, povidone, propylene glycol, sodium hydrogen phosphate, sodium dihydrogen phosphate, purified water.

Indications

Rhinitis of allergic and infectious-inflammatory etiology, sinusitis, eustachitis, hay fever.

Conjunctival edema, allergic conjunctivitis, conjunctivitis of non-infectious etiology (eg smoke, dust, exposure to wind and sun, artificial lighting).

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

oxymetazoline hydrochloride

Contraindications

Hypersensitivity, atrophic rhinitis, pregnancy, lactation period, CHF, arrhythmias, severe atherosclerosis, arterial hypertension, thyrotoxicosis, diabetes mellitus, chronic renal failure, angle-closure glaucoma, childhood.

Specifications

Category

Runny nose

Scope of the medicinal product

Ear, Throat, Nose

Release form

Spray

Manufacturer country

Italy

Package quantity, pcs

one

Scope of application

Virology

Minimum age from

6 years

Way of introduction

Intranasally

Vacation conditions

Without recipe

Volume, ml.

10 ml

Brand name

Bayer

The amount of the dosage form in the primary package

10 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Decongestant - alpha adrenergic agonist

Anatomical and therapeutic characteristics

R01AA05 Oxymetazoline

Dosage form

Dosed nasal spray

The target audience

Children

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

oxymetazoline hydrochloride 0.025 mg

Package weight, g

thirty

Mode of application

:

Intranasally.

Adults and children over 12 years old - 2 - 3 injections of Nazol in each nasal passage 2 times / day. < br> Children from 6 to 12 years old - 1 injection in each nasal passage 2 times / day. < br> Do not use the drug Nazol more often 2 times / day.

Duration of treatment: it is not recommended to use the drug for more than 3 days. < br> With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen.

If these symptoms appear, stop treatment and consult a doctor. < br> When injecting, do not tilt your head back and do not spray while lying down.

Information on technical characteristics, delivery set, country of manufacture "