Nafpenzal DC 1 syringe

DESCRIPTION

Nafpenzal DC is a drug for the prevention and treatment of mastitis in cows during the dry period. Dosage form: suspension for intracisternal administration. In appearance, the drug is a yellowish oily suspension.

COMPOSITION

Nafpenzal DC in 1 syringe contains as active substances: procaine benzylpenicillin - 300mg, dihydrostreptomycin (in the form of sulfate) - 100mg, nafcillin (in the form of sodium salt) - 100mg, as auxiliary substances: 80mg of aluminum distearate and liquid paraffin up to 3000mg.

PHARMACOLOGICAL PROPERTIES

Nafpezal DC belongs to the combined antibacterial drugs for intracisternal administration.

The combination of antibiotics that make up Nafpenzala DC has a synergistic effect against the main causative agents of mastitis, including penicillin-resistant strains of staphylococci, streptococci, Escherichia and corynebacteria.

The mechanism of action of penicillin and nafcillin is to suppress the functional activity of bacterial enzymes of transpeptidases involved in binding the main component of the cell wall of microorganisms - peptidoglycan. Blocking the synthesis of peptidoglycan leads to the destruction of the cell wall and the death of bacteria.

The mechanism of action of dihydrostreptomycin is associated with a violation of protein synthesis on the ribosomes of the bacterial cell, which leads to the death of the microbial cell.

Antibiotics are absorbed into the blood from the mammary gland to an insignificant extent and excreted in milk. The effective level of nafcillin in the secretion of the udder of cattle lasts up to 4 weeks, procaine benzylpenicillin - up to 8 weeks, dihydrostreptopimycin - up to 13 weeks after drug administration.

According to the degree of impact on the body, Nafpenzal DC belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76) and does not irritate the udder tissue in recommended doses.

The use of Nafpenzala DC does not exclude the use of other medicinal products for animals, with the exception of drugs for intracisternal administration.

INDICATIONS

Nafpenzal DC is indicated for the prevention and treatment of mastitis in dry cows.

APPLICATION

Nafpenzal DC is administered for prophylactic purposes in healthy, and for therapeutic purposes in the affected quarters of the udder intracisternally, once in a dose of 1 syringe-dispenser for 1 quarter of the udder after the last milking before transfer to the dry period, but no later than 35 days before the expected calving ...

Before using the drug, milk (secret) from the quarters of the udder is removed and disposed of, the nipple is carefully treated with a cleaning cloth, then the protective cap is removed from the syringe-dispenser, the tip of the syringe-dispenser is inserted into the nipple channel and the contents are carefully squeezed out. After that, the tip is removed, the tip of the nipple is pinched with fingers and the nipple is lightly massaged from the bottom up to better distribute the drug.

The drug is administered once.

SPECIAL INSTRUCTIONS

Milk from sick quarters is disinfected and disposed of. For food purposes, milk can be used 36 hours after calving. Milk obtained after calving cows before the expiration of the specified period may be used after boiling in animal feed. If the drug was mistakenly administered to lactating cows, milk should not be used in food for 37 days.

Slaughter of animals for meat is allowed no earlier than 14 days after the last application of Nafpenzal DC. The meat of animals that were forcedly killed before the expiration of the specified period can be used as feed for fur animals.

CONTRAINDICATIONS

A contraindication for use is the individual hypersensitivity of the animal to the components of the drug. Do not use Nafpenzal DC on cows during lactation and less than 5 weeks before calving.

OVERDOSE

Overdose symptoms when using Nafpenzal DC have not been identified.

SIDE EFFECTS

When using Nafpenzal DC in accordance with this instruction, side effects and complications are usually not observed. In case of increased individual sensitivity of the animal to the components of the drug and the appearance of signs of allergy, the use of Nafpenzala DC is discontinued and the animal is prescribed antihistamines and symptomatic therapy.

PRECAUTIONS

When working with Nafpenazl DC, you should follow the general rules of personal hygiene and safety measures provided for working with veterinary medicinal products. People with hypersensitivity to the components of the drug should avoid direct contact with Nafpenzal DC.

FIRST AID MEASURES

If the drug gets on the skin and / or mucous membranes, it is recommended to rinse them with plenty of running water. In case of allergic reactions or if the drug enters the human body, you must immediately contact a medical institution (you must have instructions for using the drug with you).

STORAGE

Store in closed manufacturer's packaging, separately from food and feed, in a dry place protected from direct sunlight, at a temperature of 2 В° C to 25 В° C. Shelf life, subject to storage conditions, is 2 years.

PACKING

Produced in 3g plastic syringes-dispensers for single use, 1 syringe per package.

Specifications

KolVUP

4

Manufacturer

Intervet

Temperature regime

from +2 to +25

Teaser

drug for the prevention and treatment of mastitis in cows during the dry period