moxonidine | Physiotens tablets are covered.pl.ob. 0.2 mg 14 pcs.

Latin name

Fiziotenz

Release form

Tablets.

Packing

14 pcs

Indications

Arterial hypertension.

Contraindications

Hypersensitivity, SSSU, SA and AV block, bradycardia (less than 50 / min), decompensated heart failure, unstable angina, severe liver failure, chronic renal failure (CC less than 30 ml / min, creatinine over 160 lmol / l, creatinine) .C caution. Parkinson's disease (severe), epilepsy, glaucoma, depression, intermittent claudication, Raynaud's disease pregnancy, childhood - there is no experience with the use.

Use during pregnancy and lactation

There is no clinical evidence of a negative effect on pregnancy. However, caution should be exercised when prescribing Physiotens to pregnant women. During treatment, it is recommended to stop breastfeeding, as moxonidine passes into breast milk.

Composition

1 coated tablet contains:

active ingredient: moxonidine 0.3 mg

excipients: lactose monohydrate povidone crospovidone magnesium stearate hypromellose ethyl cellulose macrogol 6000 talc iron oxide 2 red1 (di) 1 (red).

Dosage and administration

Inside, during or after a meal, washed down with liquid, 0.2 mg / day at a time, preferably in the morning. If necessary, increase the dose to 0.4 mg / day in 2 divided doses. The maximum daily dose is 0.6 mg. In patients with renal failure (CC 30-60 ml / min), a single dose should not exceed 0.2 mg, a daily dose of 0.4 mg.

Side effects

From the central nervous system: Headache, dizziness, drowsiness, sleep disturbance

From the cardiovascular system: Excessive decrease in blood pressure (BP), orthostatic hypotension

From the gastrointestinal tract: Dry mouth, nausea

From the skin and subcutaneous fat: Skin rash, itching, angioedema srdlp General: Asthenia

These symptoms usually gradually decrease during the first weeks of treatment.

Drug Interaction

Increases CNS inhibition of anxiolytics, barbiturates and ethanol. The resulting effect of adherence of alpha blockers to therapy is determined by their dose. Mutual reinforcement of action when jointly assigned with other antihypertensive drugs. Beta-blockers increase bradycardia, the severity of negative inno - and dromotropic action. If necessary, the abolition of both beta-blockers and moxonidine can be abolished first by beta-blockers and only moxonidine only a few days later.

Overdose

Symptoms: headache, sedation, drowsiness, excessive blood pressure decrease, dizziness, general weakness, bradycardia, dry mouth, vomiting, fatigue and stomach pain. Short-term increases in blood pressure, tachycardia, and hyperglycemia are also possible.

Treatment: There are no specific antidotes.

In case of hypotension it is recommended to restore the volume of circulating blood due to the introduction of fluid and dopamine.

Bradycardia can be stopped with atropine.

Alpha-adrenoceptor antagonists may reduce or eliminate transient hypertension when overdosed with moxonidine.

Storage conditions

In the dark place at a temperature of no higher than 25 РC.

Expiration

2 years.

Deystvuyuschee substances

Moksonydyn



pharmacy leave terms

Dosage form

dosage form

tablets

Nobel Almaty Pharmaceutical Factory AO, USA