Morpholine-Methyl-Triazolyl-Thioacetate | Thiotriazoline tablets 100 mg, 50 pcs.
Special Price
$21.34
Regular Price
$29.00
In stock
SKU
BID466953
Release form
Tablets.
Tablets.
Release form
Tablets.
Packing
50 pcs.
Pharmacological action
The pharmacological effect is due to anti-ischemic, antioxidant, membrane-stabilizing and immunomodulating properties. It prevents the death of hepatocytes, reduces the degree of their fatty infiltration and the spread of centrolobular necrosis of the liver, promotes the regeneration of hepatocytes, normalizes protein, carbohydrate, lipid and pigment exchanges. Increases the amount of synthesis and secretion of bile, normalizes its chemical composition.
Thiotriazolin® enhances the compensatory activation of anaerobic glycolysis, reduces the inhibition of oxidation processes in the Krebs cycle, while maintaining the intracellular ATP fund. The drug activates the antioxidant system and inhibits the processes of lipid oxidation in ischemic areas. Improves the rheological properties of blood (activates the fibrinolytic system). Antioxidant properties are manifested due to the presence of a sulfur ion in the structure of the molecule of Thiotriazolin®, which is characterized by redox features, and tertiary nitrogen, which binds the excess of hydrogen ions. Thiotriazolin® reacts with reactive oxygen species and lipid radicals due to the expressed reducing properties of the thiol group and prevents the occurrence of reactive oxygen species by reactivation of antiradical enzymes - superoxide dismutase, catalase and glutathione peroxidase.
Indications
Toxic lesions of the liver, including alcohol, viral and medicinal origin (antibiotics, antitumor, antituberculosis, antiviral drugs, tricyclic antidepressants, oral contraceptives, etc.).
Chronic alcoholic hepatitis with minimal to moderate activity.
Chronic viral hepatitis.
Fatty degeneration of the liver.
Cirrhosis of the liver.
Contraindications
Hypersensitivity to the components of the drug.
Renal failure.
Children's age.
Pregnancy and lactation.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Special instructions
The composition of the tablets includes sucrose - 2.8 mg per tablet, i.e. the maximum daily dose (8 tablets) contains 22.4 mg of sucrose, which should be considered in patients with diabetes.
Composition
Active ingredient: morpholinium methyl triazolyl thioacetate (thiotriazolinΩ 100 mg (in terms of 100% substance).
Excipients: potato starch, low molecular weight povidone, sucrose, microcrystalline cellulose, calcium stearate.
Dosage and Administration
Inside. Thiotriazolin® is prescribed for 1 to 2 tablets 3-4 times a day for 20 to 30 days. The duration of the course of treatment is determined by the doctor individually, depending on the severity and characteristics of the course of the disease.
Side effects
Thiotriazolin® is generally well tolerated. In clinical use of Thiotriazolin®, isolated cases of adverse reactions were observed:
From the gastrointestinal tract: nausea, dry mouth, bloating.
From the central and peripheral nervous system: general weakness, dizziness, tinnitus.
From the cardiovascular system: tachycardia, increased blood pressure, pain in the heart, arrhythmias.
From the respiratory system: very rarely - shortness of breath, asthma attacks.
Allergic reactions: hypersensitivity reactions, fever, very rarely - Quincke edema.
From the skin: itching, flushing of the skin, urticaria.
Overdose
Cases of overdose unknown. When ingesting a large amount of the drug - it is necessary to do a gastric lavage. The treatment is symptomatic.
Storage Conditions
Store in a dry, dark place, out of the reach of children, at temperatures between 15 РC and 25 РC.
Expiration
3 years.
Active ingredient
Morpholin-Methyl-triazol-thioacetate
Terms leave through pharmacies
In retseptu
lekarstvennaja form
tablets
Tablets.
Packing
50 pcs.
Pharmacological action
The pharmacological effect is due to anti-ischemic, antioxidant, membrane-stabilizing and immunomodulating properties. It prevents the death of hepatocytes, reduces the degree of their fatty infiltration and the spread of centrolobular necrosis of the liver, promotes the regeneration of hepatocytes, normalizes protein, carbohydrate, lipid and pigment exchanges. Increases the amount of synthesis and secretion of bile, normalizes its chemical composition.
Thiotriazolin® enhances the compensatory activation of anaerobic glycolysis, reduces the inhibition of oxidation processes in the Krebs cycle, while maintaining the intracellular ATP fund. The drug activates the antioxidant system and inhibits the processes of lipid oxidation in ischemic areas. Improves the rheological properties of blood (activates the fibrinolytic system). Antioxidant properties are manifested due to the presence of a sulfur ion in the structure of the molecule of Thiotriazolin®, which is characterized by redox features, and tertiary nitrogen, which binds the excess of hydrogen ions. Thiotriazolin® reacts with reactive oxygen species and lipid radicals due to the expressed reducing properties of the thiol group and prevents the occurrence of reactive oxygen species by reactivation of antiradical enzymes - superoxide dismutase, catalase and glutathione peroxidase.
Indications
Toxic lesions of the liver, including alcohol, viral and medicinal origin (antibiotics, antitumor, antituberculosis, antiviral drugs, tricyclic antidepressants, oral contraceptives, etc.).
Chronic alcoholic hepatitis with minimal to moderate activity.
Chronic viral hepatitis.
Fatty degeneration of the liver.
Cirrhosis of the liver.
Contraindications
Hypersensitivity to the components of the drug.
Renal failure.
Children's age.
Pregnancy and lactation.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Special instructions
The composition of the tablets includes sucrose - 2.8 mg per tablet, i.e. the maximum daily dose (8 tablets) contains 22.4 mg of sucrose, which should be considered in patients with diabetes.
Composition
Active ingredient: morpholinium methyl triazolyl thioacetate (thiotriazolinΩ 100 mg (in terms of 100% substance).
Excipients: potato starch, low molecular weight povidone, sucrose, microcrystalline cellulose, calcium stearate.
Dosage and Administration
Inside. Thiotriazolin® is prescribed for 1 to 2 tablets 3-4 times a day for 20 to 30 days. The duration of the course of treatment is determined by the doctor individually, depending on the severity and characteristics of the course of the disease.
Side effects
Thiotriazolin® is generally well tolerated. In clinical use of Thiotriazolin®, isolated cases of adverse reactions were observed:
From the gastrointestinal tract: nausea, dry mouth, bloating.
From the central and peripheral nervous system: general weakness, dizziness, tinnitus.
From the cardiovascular system: tachycardia, increased blood pressure, pain in the heart, arrhythmias.
From the respiratory system: very rarely - shortness of breath, asthma attacks.
Allergic reactions: hypersensitivity reactions, fever, very rarely - Quincke edema.
From the skin: itching, flushing of the skin, urticaria.
Overdose
Cases of overdose unknown. When ingesting a large amount of the drug - it is necessary to do a gastric lavage. The treatment is symptomatic.
Storage Conditions
Store in a dry, dark place, out of the reach of children, at temperatures between 15 РC and 25 РC.
Expiration
3 years.
Active ingredient
Morpholin-Methyl-triazol-thioacetate
Terms leave through pharmacies
In retseptu
lekarstvennaja form
tablets
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