Miramistin solution for local approx. with a gynecological nozzle 0.01%, 50ml

Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis.
In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.
Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.
Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.
Obstetrics-Gynecology:prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).
Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty.
Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet.
Individual prevention of sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.).
Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.

The drug is ready for use.

Instructions for using the spray pack:

1. Remove the cap from the bottle, also remove the urological applicator from the 50 ml bottle.

2. Remove the supplied spray nozzle from the protective packaging.

3. Attach the spray nozzle to the bottle.

4. Activate the spray nozzle by pressing again.

Directions for use of the 50 ml or 100 ml pack with a gynecological attachment:

1. Remove the cap from the bottle.

2. Remove the enclosed gynecological attachment from the protective packaging.

3. Attach the gynecological attachment to the bottle without removing the urological applicator.

Otorhinolaryngology.
With purulent sinusitis - during puncture, the maxillary sinus is washed with a sufficient amount of the drug.
Tonsillitis, pharyngitis and laryngitis are treated by gargling and / or irrigation with a spray nozzle, 3-4 times pressing, 3-4 times a day.
The amount of the preparation for one rinse is 10-15 ml.
In children. In case of acute pharyngitis and / or exacerbation of chronic tonsillitis, irrigation of the pharynx is carried out using a spray nozzle. Children aged 3-6: by pressing once on the head of the spray nozzle (3-5 ml per irrigation), 3-4 times a day; children aged 7-14 years by double pressing (5-7 ml per irrigation), 3-4 times a day; children over 14 years old by pressing 3-4 times (10-15 ml per irrigation), 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.

Dentistry.
For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Surgery, traumatology, combustiology.
For prophylactic and therapeutic purposes, the surface of wounds and burns is irrigated, wounds and fistulous passages are loosely tamponed, gauze tampons moistened with the drug are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics, gynecology.
In order to prevent postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), in childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. For the convenience of vaginal irrigation, the use of a gynecological nozzle is recommended. Introduce the contents of the bottle into the vagina with the help of a gynecological nozzle and irrigate.
When women are delivered by cesarean section, immediately before the operation, the vagina is treated, during the operation - the uterine cavity and an incision on it, and in the postoperative period, tampons moistened with the drug are inserted into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out in a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of drug electrophoresis.

Venereology.
For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after intercourse. Introduce the contents of the bottle with the urological applicator into the urethra for 2-3 minutes: men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml). For convenience, the use of a gynecological attachment is recommended. Treat the skin of the inner surfaces of the thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours.

Urology.
In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times a day, the course is 10 days.

active substance: benzyldimethyl [3- (myristoylamino) propyl] ammonium chloride monohydrate (in terms of anhydrous substance) - 0.1 g
auxiliary substance: purified water - up to 1 l

Individual intolerance to the drug.

Tradename:

MiramistinЃ

Chemical name:

Benzyldimethyl [3- (myristoylamino) propyl] ammonium chloride monohydrate

Dosage form:

solution for topical use.

Composition:

active substance: benzyldimethyl [3- (myristoylamino) propyl] ammonium chloride monohydrate (in terms of anhydrous substance) - 0.1 g
auxiliary substance: purified water - up to 1 l

Description:

colorless, clear liquid, foaming on shaking.

Pharmacotherapeutic group:

antiseptic.

Pharmacological properties

Miramistin has a wide spectrum of antimicrobial activity, including hospital strains resistant to antibiotics.
The drug has a pronounced bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae , etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp. , Etc.), aerobic and anaerobic bacteria, determined microbial associations, including hospital strains with multidrug resistance to antibiotics.
Has antifungal effect on ascomycetes of the genus Aspergillus and genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata , etc.) and yeast-like fungi(Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) , etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenophyton-phytonophyton, Epichophyton-Epidermon Microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.
Possesses antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.).
Miramistin acts on sexually transmitted pathogens(Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae , etc.).
Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, by activating the absorption and digestion functions of phagocytes, potentiates the activity of the monocytic-macrophage system. It has a pronounced hyperosmolar activity, as a result of which it relieves wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab. Does not damage granulation and viable skin cells, does not inhibit marginal epithelization.
Does not possess local irritant and allergenic properties.
Pharmacokinetics. When applied topically, miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Indications for use

Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis.
In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.
Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.
Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.
Obstetrics-Gynecology:prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).
Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty.
Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet.
Individual prevention of sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.).
Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.

Contraindications

Individual intolerance to the drug.

Method of administration and dosage

The drug is ready for use.

Instructions for using the spray pack:

1. Remove the cap from the bottle, also remove the urological applicator from the 50 ml bottle.

2. Remove the supplied spray nozzle from the protective packaging.

3. Attach the spray nozzle to the bottle.

4. Activate the spray nozzle by pressing again.

Directions for use of the 50 ml or 100 ml pack with a gynecological attachment:

1. Remove the cap from the bottle.

2. Remove the enclosed gynecological attachment from the protective packaging.

3. Attach the gynecological attachment to the bottle without removing the urological applicator.

Otorhinolaryngology.
With purulent sinusitis - during puncture, the maxillary sinus is washed with a sufficient amount of the drug.
Tonsillitis, pharyngitis and laryngitis are treated by gargling and / or irrigation with a spray nozzle, 3-4 times pressing, 3-4 times a day.
The amount of the preparation for one rinse is 10-15 ml.
In children. In case of acute pharyngitis and / or exacerbation of chronic tonsillitis, irrigation of the pharynx is carried out using a spray nozzle. Children aged 3-6: by pressing once on the head of the spray nozzle (3-5 ml per irrigation), 3-4 times a day; children aged 7-14 years by double pressing (5-7 ml per irrigation), 3-4 times a day; children over 14 years old by pressing 3-4 times (10-15 ml per irrigation), 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.

Dentistry.
For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Surgery, traumatology, combustiology.
For prophylactic and therapeutic purposes, the surface of wounds and burns is irrigated, wounds and fistulous passages are loosely tamponed, gauze tampons moistened with the drug are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics, gynecology.
In order to prevent postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), in childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours, for 5 days. For the convenience of vaginal irrigation, the use of a gynecological nozzle is recommended. Introduce the contents of the bottle into the vagina with the help of a gynecological nozzle and irrigate.
When women are delivered by cesarean section, immediately before the operation, the vagina is treated, during the operation - the uterine cavity and an incision on it, and in the postoperative period, tampons moistened with the drug are inserted into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out in a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of drug electrophoresis.

Venereology.
For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after intercourse. Introduce the contents of the bottle with the urological applicator into the urethra for 2-3 minutes: men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml). For convenience, the use of a gynecological attachment is recommended. Treat the skin of the inner surfaces of the thighs, pubis, genitals. After the procedure, it is recommended not to urinate for 2 hours.

Urology.
In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times a day, the course is 10 days.

Side effect

In some cases, a slight burning sensation may occur at the site of application, which disappears on its own, after 15-20 seconds, and does not require discontinuation of the drug. Allergic reactions.

Interaction with other medicinal products

With simultaneous use with antibiotics, an increase in their antibacterial and antifungal properties has been noted.

Release form

Solution for topical application 0.01%.
Polyethylene bottles with urological applicator with a screw cap 50 ml, 100 ml.
Polyethylene bottles 50 ml with a urological applicator with a screw-on cap, complete with a spray nozzle.
Polyethylene bottles 50 ml, 100 ml with a urological applicator with a screw-on cap, complete with a gynecological nozzle.
Polyethylene bottles 100 ml, 150 ml, 200 ml complete with a spray nozzle or equipped with a spray pump and a protective cap.
Polyethylene bottles 500 ml with screw cap with first opening control.
Each bottle of 50 ml, 100 ml, 150 ml, 200 ml, 500 ml, together with instructions for use, are placed in a cardboard box.
For hospitals: 12 bottles of 500 ml without a pack with an equal number of instructions for use are placed in a cardboard box for consumer packaging.

Storage conditions

Store at a temperature not exceeding 25 ? C.
Keep out of the reach of children.

Shelf life

3 years. Do not use after the expiration date.

Conditions of dispensing from pharmacies

Without recipe.