Milk thistle meal powder dietary supplement, 100g

• toxic liver damage (alcoholism, intoxication with halogenated hydrocarbons, heavy metal compounds, medicinal liver damage) and their prevention;

• chronic hepatitis;

• cirrhosis of the liver (as part of complex therapy);

• conditions after infectious and toxic hepatitis; dystrophy and fatty liver infiltration;

• correction of lipid metabolism disorders.

For adults and children over 12 years old, take 1 teaspoon of the powder (3.5 g) daily with food, drinking plenty of fluids.

Duration of admission is 1 month.

Milk thistle extract (silymarin) + excipients

Hypersensitivity

pharmachologic effect

Milk thistle interacts with free radicals in the liver and reduces their toxicity. By interrupting the process of lipid peroxidation, it prevents further destruction of cellular structures.

In damaged hepatocytes, it stimulates the synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA polymerase A), stabilizes cell membranes, prevents the loss of cellular components and intracellular enzymes (transaminases), accelerates the regeneration of liver cells.

It inhibits the penetration of certain hepatotoxic substances into the cells (venoms of the mushroom of the pale toadstool). Undergoes enterohepatic circulation. Metabolized in the liver by conjugation. It is excreted mainly in the bile in the form of glucuronides and sulfates, to a small extent in the urine. Does not cumulate.

After repeated oral administration of 140 mg 3 times a day, a stable concentration is achieved. Improves the general condition of patients with liver diseases, reduces subjective complaints, normalizes laboratory parameters (activity of transaminases, gamma-glutamyltransferase, alkaline phosphatase, bilirubin level).

Long-term use significantly increases the survival rate of patients with liver cirrhosis.

Indications

• toxic liver damage (alcoholism, intoxication with halogenated hydrocarbons, heavy metal compounds, medicinal liver damage) and their prevention;

• chronic hepatitis;

• cirrhosis of the liver (as part of complex therapy);

• conditions after infectious and toxic hepatitis; dystrophy and fatty liver infiltration;

• correction of lipid metabolism disorders.

Contraindications

Hypersensitivity

Composition

Milk thistle extract (silymarin) + excipients

Method of administration and dosage

For adults and children over 12 years old, take 1 teaspoon of the powder (3.5 g) daily with food, drinking plenty of fluids.

Duration of admission is 1 month.

Drug interactions

With the combined use of Milk thistle with oral hormonal contraceptives and drugs intended for hormone replacement therapy, it is possible to reduce the effects of the latter.

Storage conditions

Store in a dry, dark place at a temperature not exceeding + 25 ? C.

Shelf life

2 years

Conditions of dispensing from pharmacies

Without recipe