Milbemax anthelmintic for cats with beef flavor 2 tablets

DESCRIPTION

Melbimax is an anthelmintic for cats. In appearance, it is an elongated tablet with beveled edges and a transverse notch on one side. Tablets for adult cats are red coated.

COMPOSITION

As active ingredients milbemycin oxime and praziquantel, as well as auxiliary components. 1 tablet contains 16 mg of milbemycin oxime and 40 mg of praziquantel.

PHARMACOLOGICAL PROPERTIES

Milbemycin oxime and praziquantel exhibit synergistic action and, in combination, have a broad spectrum of action on larval and sexually mature forms of nematodes and cestodes. Milbemycin oxime, which is part of the preparation, belongs to the group of macrocyclic lactones released as a result of the enzymatic activity of Streptomyces hygroscopicus var. Aureolacrimosus. Milbemycin oxime is active against nematodes parasitizing in the gastrointestinal tract of cats, as well as the larvae of the nematode Dirofilaria immitis. The mechanism of action of milbemycin is due to an increase in the permeability of cell membranes for chlorine ions, which leads to overpolarization of the membranes of cells of the nervous and muscle tissue, paralysis and death of the parasite. The maximum concentration of milbemycin oxime in blood plasma is reached after 2 hours. The compound is excreted from the body mainly unchanged, the half-life is about 13 hours after oral administration of the drug. Praziquantel is an acylated pyrazine-isoquinoline derivative with a pronounced effect against cestodes and nematodes. By increasing the permeability of the parasite's cell membranes for calcium ions, it causes membrane depolarization, muscle contraction and destruction of the tegument, which leads to the death of the parasite and promotes its excretion from the animal's body. The maximum concentration of praziquantel in blood plasma is reached after 1 hour. The compound is excreted from the body mainly in the form of inactive metabolites in the urine, the half-life is about 3 hours after oral administration of the drug. Milbemax belongs to the group of compounds that are moderately dangerous for warm-blooded animals; in recommended doses, it does not have a sensitizing effect, embryotoxic and teratogenic action. Well tolerated by cats of different breeds and ages. The drug is toxic to fish and other aquatic organisms.

INDICATIONS

It is prescribed for prophylactic and therapeutic purposes for deworming cats with nematodes (toxocariasis, ankylostomiasis) and cestodoses (echinococcosis, dipylidiosis, teniasis).

DOSES AND METHOD OF APPLICATION

Milbemax is administered to cats orally once, individually in the morning with a small amount of food, or injected forcibly on the root of the tongue after ingestion of food in a minimum therapeutic dose of 2 mg of milbemycin oxime and 5 mg of praziquantel per 1 kg of animal weight.

Elderly cats, weight Dosage

2 - 4 kg ? pills

4 - 8 kg 1 tablet

8 - 12 kg 1? pills

It is necessary to monitor the consumption of the drug. No prior fasting diet or laxatives are required. Milbemax can be used in kittens from 6 weeks of age. For pregnant cats, the drug is used in the last third of the pregnancy, lactating - 2 - 3 weeks after lambing under the supervision of a veterinarian. Preventive deworming is recommended on a quarterly basis, as well as before vaccination and mating in the above doses.

SIDE EFFECTS

Allergic reactions are possible in animals hypersensitive to the components of milbemax. With proper use and dosage, side effects are usually not observed. In case of an overdose, some cats may experience tremors, the symptoms of which disappear spontaneously within 24 hours and do not require the use of drugs.

CONTRAINDICATIONS

Increased individual sensitivity to the drug. It is forbidden to prescribe milbemax to kittens younger than 6 weeks of age, cats in the first two-thirds of the gestation period, as well as sick with infectious diseases and recovering animals. Not recommended for cats weighing less than 0.5 kg. Should not be used in animals with impaired renal and liver function.

SPECIAL INSTRUCTIONS

No special precautions are taken.

STORAGE AND SHELF LIFE

With precaution according to the list B. In a dry, dark place inaccessible to children and animals at temperatures from 0 to 30 В° C. The shelf life is 3 years. Shelf life after opening the blister is 6 months.

PACKAGING

Packaged in 2 tablets in foil blisters, which are packed in cardboard boxes.

Specifications

KolVUP

24

Manufacturer

Elanco

Teaser

anthelmintic drug for cats