Metrogyl Denta gel dental tube 20 g No. 1

Release form, composition and packaging

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Opalescent dental gel, soft, white or almost white.

1 g

metronidazole benzoate 16 mg,

which corresponds to the content of metronidazole 10 mg

chlorhexidine bigluconate 20% solution 2.5 mg,

which corresponds to the content of chlorhexidine bigluconate 0.5 mg

propylene glycol - 50 mg, carbomer-980 - 15 mg, disodium edetate - 0.5 mg, sodium saccharinate - 1 mg, levomenthol - 5 mg, sodium hydroxide - 4 mg, water - sc.

required

up to 1 g. 5 g - laminated plastic tubes (1) - cardboard packs.

10 g - laminated plastic tubes (1) - cardboard packs.

20 g - laminated plastic tubes (1) - cardboard packs.

pharmachologic effect

Combined antimicrobial drug, the effectiveness of which is due to the presence of two antibacterial components in its composition. Metronidazole is active against anaerobic bacteria that cause periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincentii, Bacteroides melaninogenicus, Selenomonas spp. Chlorhexidine is an antiseptic and antimicrobial agent, active against gram-negative and gram-positive aerobic and anaerobic bacteria: Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis. Some strains of Pseudomonas spp., Proteus spp. Are weakly sensitive to chlorhexidine, as well as acid-resistant forms of bacteria, bacterial spores.Does not violate the functional activity of lactobacilli.

Pharmacokinetics

When applied topically, Metrogyl Denta® gel is practically not absorbed.

Indications for use

Infectious and inflammatory diseases of the periodontal and oral mucosa: - acute and chronic gingivitis

- Acute necrotizing ulcerative gingivitis of Vincent

- acute and chronic periodontitis

- youthful periodontitis

- periodontal disease complicated by gingivitis

- aphthous stomatitis

- cheilitis

- inflammation of the oral mucosa when wearing prostheses

- post-extraction alveolitis

- periodontitis, periodontal abscess (as part of combination therapy).

Contraindications for use

- diseases of the blood system, incl.

history

- diseases of the peripheral and central nervous system

- age under 18

- hypersensitivity to metronidazole, chlorhexidine, nitroimidazole derivatives and other components of the drug.

Dosage regimen

Topically, for dental use only. In case of gingivitis, Metrogyl Denta® is applied to the gum area 2 times / day with a thin layer (with a finger or with a cotton swab), it is not recommended to wash off the gel. The duration of the course of therapy is on average 7-10 days. After applying the gel, you should refrain from drinking and eating for 30 minutes. In case of periodontitis, after removing dental deposits, periodontal pockets are treated with a preparation and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel on his own: the drug should be applied to the gum area 2 times / day for 7-10 days. In case of aphthous stomatitis, the gel is applied to the affected area of ​​the oral mucosa 2 times / day for 7-10 days.For the prevention of exacerbations of chronic gingivitis and periodontitis, the gel is applied to the gum area 2 times / day for 7-10 days. Preventive courses are carried out 2-3 times a year. For the prevention of post-extraction alveolitis, the drug is used to treat the well after tooth extraction, then the gel is used on an outpatient basis 2-3 times / day for 7-10 days.

Overdose

Symptoms: Accidental or deliberate swallowing of large amounts of gel may cause increased side effects, mainly due to metronidazole (chlorhexidine

Name ENG

METROGYL DENTA

Clinical and pharmacological group

Antimicrobial drug for topical use in dentistry

ATX code

Other antimicrobial drugs

Dosage

10mg / g + 0.5mg / g x 20g

Structure

metronidazole benzoate 16 mg., this corresponds to the content of metronidazole 10 mg.

chlorhexidine bigluconate 20% solution 2.5 mg, which corresponds to the content of chlorhexidine bigluconate 500 μg.

Excipients: propylene glycol, carbomer-940, disodium edetate, sodium saccharinate, levomenthol, sodium hydroxide, water.

Indications

Infectious and inflammatory diseases of the periodontal and oral mucosa:

acute and chronic gingivitis

acute necrotizing ulcerative gingivitis of Vincent

acute and chronic periodontitis

juvenile periodontitis

periodontal disease complicated by gingivitis

aphthous stomatitis

cheilitis

inflammation of the oral mucosa when wearing prostheses

postextraction alveolitis (inflammation of the socket after tooth extraction)

periodontitis, periodontal abscess (as part of combination therapy).

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

chlorhexidine bigluconate (20% solution), metronidazole (in the form of benzoate)

Contraindications

Individual intolerance to metronidazole, chlorhexidine, as well as nitroimidazole derivatives, intolerance to any components that make up the drug

children under 6 years of age.

Specifications

Category

Dentistry

Scope of the drug

Dentistry

Release form

Gel

Manufacturer country

India

Package quantity, pcs

one

Scope of application

Dentistry

Way of introduction

On the mucous membrane

Vacation conditions

Without recipe

Brand name

Metrogyl Denta

The amount of the dosage form in the primary package

20 g

Primary packaging type

Laminated plastic tube

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antimicrobial agent

Anatomical and therapeutic characteristics

A01AB11 Other preparations

Dosage form

Dental gel

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

10 mg + 0.5 mg / 1 g

Package weight, g

twenty

Mode of application

:

Topically, for dental use only. In case of gum disease (gingivitis), adults and children over 6 years of age, Metrogyl Denta® is applied to the gum area with a thin layer, with a finger or with a cotton swab, 2 times a day. After applying the gel, you should refrain from drinking and eating for 30 minutes. It is not recommended to wash off the gel. The duration of the course of treatment is on average 7-10 days. In case of periodontitis after the removal of dental deposits, periodontal pockets are treated with Metrogyl Denta® gel and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently: Metrogyl Denta® is applied to the gum area 2 times a day for 7-10 days.In case of aphthous stomatitis, Metrogyl Denta® is applied to the affected area of ​​the oral mucosa 2 times a day for 7-10 days. To prevent exacerbations of chronic gingivitis and periodontitis, Metrogyl Denta® gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses of treatment are carried out 2-3 times a year. For the prevention of post-extraction alveolitis after tooth extraction, the socket is treated with Metrogyl Denta® gel, then the gel is applied 2-3 times a day for 7-10 days.For the prevention of post-extraction alveolitis after tooth extraction, the socket is treated with Metrogyl Denta® gel, then the gel is applied 2-3 times a day for 7-10 days.To prevent post-extraction alveolitis after tooth extraction, the socket is treated with Metrogyl Denta® gel, then the gel is applied 2-3 times a day for 7-10 days.

Information on technical characteristics, delivery set, country of manufacture