Methyluracil tablets 500mg, No. 50

• leukopenia (mild forms, including those resulting from chemotherapy of malignant neoplasms, with X-ray and radiation therapy),

• agranulocytic tonsillitis,

• alimentary toxic aleukia,

• anemia, thrombocytopenia,

• intoxication with benzene,

• radiation sickness,

• convalescence (after severe infections),

• peptic ulcer of the stomach and duodenum,

Inside, during or after meals, 500 mg 4 times / day (if necessary, up to 6 times / day); children from 3 to 8 years old - 250 mg, over 8 years old - 250-500 mg 3 times / day. The course for diseases of the digestive tract - 30-40 days; in other cases it may be shorter

dioxomethyltetrahydropyrimidine (methyluracil)

• leukemia (leukemic forms, especially myeloid),

• lymphogranulomatosis,

• hemoblastosis,

• malignant diseases of the bone marrow.

Clinical and pharmacological groups

• A drug that activates metabolism in tissues, improves trophism and stimulates the regeneration process

• Leukopoiesis stimulant

Pharmaco-therapeutic group: Tissue regeneration stimulant

pharmachologic effect

Possesses anabolic activity. It has a hematopoietic, leukopoietic, immunostimulating, anti-inflammatory effect. By normalizing nucleic acid metabolism, it accelerates the processes of regeneration in wounds, accelerating the growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of the mucous membrane of the gastrointestinal tract), stimulates erythro- and leukopoiesis, cellular and humoral factors of immunity.

Indications

Leukopenia (mild forms, including those resulting from chemotherapy of malignant neoplasms, during X-ray and radiation therapy), agranulocytic angina, alimentary toxic aleukia, anemia, thrombocytopenia, benzene intoxication, radiation sickness, convalescence (after severe infections), peptic ulcer stomach and duodenum (as part of combination therapy), sluggish wounds, burns, bone fractures, hepatitis, pancreatitis.

Dosage regimen

Inside, during or after meals.

Adults - 500 mg 4 times a day. (if necessary - up to 6 times a day, the maximum daily dose is 3 g);

Children from 3 to 8 years old - 250 mg 3 times a day. (the maximum daily dose is 750 mg);

Children from 8 to 14 years old - 250-500 mg 3 times a day. (the maximum daily dose is 1.5 g).

The course for diseases of the gastrointestinal tract - 30-40 days; in other cases it may be shorter.

Side effect

Allergic reactions, headache, dizziness, heartburn.

Contraindications for use

Hypersensitivity, leukemia (leukemic forms, especially myeloid), lymphogranulomatosis, hemoblastosis, malignant neoplasms of the bone marrow, children up to 3 years of age.

Application during pregnancy and lactation

During pregnancy and lactation, the intended benefit to the mother and the potential risk to the fetus and child should be weighed.

Application in children

Contraindicated in children under 3 years of age.

Overdose

In clinical use, cases of overdose have not been registered until this time.

Drug interactions

Enhances the anti-radiation effect of cystamine.

Storage conditions

Store the drug in a dry, dark place at a temperature not exceeding 25 ? C. Keep out of the reach of children.

Shelf life

The shelf life is 5 years. Do not use after the expiration date printed on the package.

Terms of sale

The drug is available with a prescription.