Magnelis B6 tab. p / o No. 50

Dosage form

Film-coated tablets

Structure

magnesium lactate 470 mg

pyridoxine hydrochloride 5 mg

Excipients: sucrose, povidone (Kollidone 30), Kollidone SR (polyvinyl acetate, povidone, sodium lauryl sulfate, silicon dioxide), magnesium stearate, sodium carmellose (sodium carboxymethylcellulose), talc.

Shell composition: sucrose, kaolin (white clay), gelatin, acacia gum (gum arabic), white beeswax, carnauba wax, talc, titanium dioxide.

pharmachologic effect

A drug that replenishes magnesium deficiency.

Magnesium is a vital element that is found in all tissues of the body and is essential for the normal functioning of cells.

Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, has an antispasmodic, antiarrhythmic and antiplatelet effect.

The body receives magnesium from food.

Lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy, use of diuretics).

Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system.

Improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

Serum magnesium content of 12 to 17 mg / l (0.5-0.7 mmol / l) indicates moderate magnesium deficiency

below 12 mg / l (0.5 mmol / l) - about severe magnesium deficiency.

Pharmacokinetics

Suction

After taking the drug inside, the absorption of magnesium from the gastrointestinal tract is 50%.

Withdrawal

It is excreted mainly by the kidneys.

In the kidneys, after glomerular filtration, 70% of the magnesium present in the plasma is present its reabsorption in the renal tubules is 95-97%.

Side effects

From the digestive system: abdominal pain, constipation, nausea, vomiting, flatulence.

Allergic reactions: Allergic reactions are possible.

Selling features

Available without a prescription

Special conditions

If it is necessary to use the drug in patients with diabetes mellitus, it should be borne in mind that the tablets contain sucrose as an excipient.

In the case of concomitant calcium deficiency, the magnesium deficiency should be corrected before taking calcium supplements.

Indications

established magnesium deficiency, isolated or associated with other deficiency conditions.

Contraindications

- severe renal failure (CC less than 30 ml / min)

- phenylketonuria

- children under 6 years old

- hypersensitivity to drug components.

The drug should be used with caution in patients with moderate renal impairment.

there is a risk of developing hypermagnesemia.

Drug interactions

With the simultaneous use of drugs containing phosphates or calcium salts, a significant decrease in the absorption of magnesium from the gastrointestinal tract is possible.

Magnesium preparations reduce the absorption of tetracycline, it is recommended to separate the intake of these drugs at 3-hour intervals.

Magnesium reduces the effect of oral thrombolytic agents, reduces the absorption of iron.

Vitamin B6 inhibits the activity of levodopa.

Dosage

Adults are recommended to prescribe 6-8 tablets / Children over 6 years of age (weighing more than 20 kg) - 4-6 tablets / The daily dose should be divided into 2-3 doses.

Treatment should be discontinued after normalization of the concentration of magnesium in the blood.

The drug should be taken with meals with a glass of water.

Overdose

drop in blood pressure, nausea, vomiting, slowing reflexes, anuria, respiratory depression, coma, cardiac arrest

Name ENG

Magnelis B6

Clinical and pharmacological group

Magnesium pyridoxine

ATX code

Combination of various magnesium salts

Dosage

470mg + 5mg

Structure

1 tablet contains magnesium lactate 470 mg, pyridoxine hydrochloride 5 mg

excipients: sucrose, povidone (Kollidone 30), Kollidone SR (polyvinyl acetate, povidone, sodium lauryl sulfate, silicon dioxide), magnesium stearate, sodium carmellose (sodium carboxymethylcellulose), talc.

Indications

Established magnesium deficiency isolated or associated with other deficiency conditions.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Hypersensitivity to drug components

severe renal failure (CC less than 30 ml / min)

phenylketonuria

children under 6 years of age.

The drug should be used with caution in patients with moderate renal impairment.

there is a risk of developing hypermagnesemia.

INN / Active ingredient

Pyridoxine, magnesium lactate

Specifications

Category

Balance potassium and magnesium

Scope of the drug

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

fifty

Minimum age from

6 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

OTCPharm

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Magnesium drug

Anatomical and therapeutic characteristics

A12CC01 Magnesium chloride

Dosage form

Film-coated tablets

The target audience

Children

Dosage (volume) of the substance in the preparation

magnesium lactate 470 mg, pyridoxine hydrochloride 5 mg

Expiration date in days

1095

Package weight, g

thirty

Mode of application

:

Adults are recommended to prescribe 6-8 tablets per day.

Children over 6 years old (weighing more than 20 kg) - 4-6 tablets per day.

Information on technical characteristics, delivery set, country of manufacture