Maalox - a bottle of 250 ml suspension, heartburn and pain in the stomach
Category
Heartburn
Scope of the medicinal product
Gastrointestinal tract
Release form
Oral suspension
Manufacturer country
Italy
Package quantity, pcs
one
the white suspension is homogeneous after shaking.
Pharmacodynamics
Aluminum hydroxide and magnesium hydroxide neutralize free hydrochloric acid of gastric juice, without causing its secondary hypersecretion.
In addition, an increase in the pH of gastric juice while taking Maalox ® leads to a decrease in the activity of pepsin in the gastric juice.
The drug also has an adsorbent and enveloping effect, due to which the effect of damaging factors on the mucous membrane of the esophagus and stomach is reduced.
Pharmacokinetics
Magnesium hydroxide and aluminum hydroxide are considered topical antacids.
Due to low absorption, they do not have a systemic effect.
Name ENG
MAALOX
Clinical and pharmacological group
Antacid drug
ATX code
A02AX
Dosage
magnesium hydroxide (in the form of a gel) - 4.0 g, aluminum hydroxide (in the form of a gel) - 3.5 g,
in terms of aluminum oxide 2.3 g
Structure
100 ml of suspension contains:
active substances:
magnesium hydroxide (in the form of a gel) - 4.0 g, aluminum hydroxide (in the form of a gel) - 3.5 g,
in terms of aluminum oxide 2.3 g
auxiliary substances: hydrochloric acid 10% - 0.52815 g, citric
acid monohydrate - 0.0655 g, peppermint leaves oil - 0.0126 g, mannitol - 0.250
g, domiphene bromide - 0.00422 g, sodium saccharinate - 0.028 g, sorbitol 70% - 1.429 g,
hydrogen peroxide 30% - 0.065 g, purified water up to 100 ml.
Indications
Peptic ulcer and duodenal ulcer in the acute phase.
- Acute gastroduodenitis, chronic gastroduodenitis with normal or
increased secretory function in the acute phase.
- Hernia of the esophageal opening of the diaphragm, reflux esophagitis.
- Dyspeptic phenomena such as discomfort, gastralgia, heartburn (after
excessive use of ethanol, nicotine, coffee, taking medicinal
means, errors in the diet).
- Discomfort or pain in the epigastrium, heartburn, sour belching after errors in
diet, excessive consumption of alcohol, coffee, nicotine, etc.
Storage conditions and periods
At a temperature not higher than 25 degrees.
(do not freeze).
Expiration date: 3 years
after opening - 6 months
Contraindications
Severe renal failure.
- Hypersensitivity to active substances and other components
drug.
- Fructose intolerance (due to the presence of sorbitol in the preparation).
- Children and adolescents up to 15 years old.
- Hypophosphatemia.
Carefully
- Aluminum hydroxide can cause constipation, overdose of magnesium salts can
lead to a weakening of intestinal peristalsis
in patients from the group
increased risk (patients with renal impairment, elderly people)
taking high doses of the drug may cause or worsen bowel obstruction
and intestinal obstruction.
- Aluminum hydroxide is poorly absorbed in the gastrointestinal tract, therefore,
in patients with normal renal function, systemic exposure is rare.
Long-term treatment, the use of excessively high doses of the drug, or
the use of normal doses of the drug against the background of a low intake of phosphates with
food can lead to phosphate deficiency (due to the binding of aluminum with
phosphate), which is accompanied by increased bone resorption and
hypercalciuria with the risk of osteomalacia.
Treating patients at risk
development of phosphate deficiency or prolonged use of the drug should
exercise under medical supervision.
- With renal failure with prolonged use, an increase in
plasma concentrations of magnesium and aluminum.
In these patients with prolonged
the use of the drug in high doses may develop encephalopathy, dementia,
microcytic anemia or worsening dialysis-induced osteomalacia.
- In patients with porphyria on hemodialysis
during pregnancy and
breastfeeding (see the section Use during pregnancy and during breastfeeding
feeding ")
- With Alzheimer's disease
INN / Active ingredient
magnesium hydroxide (in the form of a gel)
aluminum hydroxide (gel)
Specifications
Category
Heartburn
Scope of the medicinal product
Gastrointestinal tract
Release form
Oral suspension
Manufacturer country
Italy
Package quantity, pcs
one
Minimum age from
15 years
Way of introduction
Through the mouth
Vacation conditions
Without recipe
Volume, ml.
250 ml
Brand name
Sanofi
The amount of the dosage form in the primary package
250 ml
Primary packaging type
Bottle
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
Antacid
Anatomical and therapeutic characteristics
A02AX Antacids, in combination with other drugs
Dosage form
Suspension for oral administration
Packaging
Cardboard box
The target audience
Children
Expiration date in days
912
Package weight, g
250
Mode of application
:
Inside.
Shake the bottle before use.
Adults and adolescents over 15 years old: 15 ml (1 tablespoon) 3-4 times a day after 1
2 hours after meals and at night.
The dose should not exceed 6 tablespoons per day.
When
reflux esophagitis, the drug is taken a short time after eating.
A course of treatment
should not exceed 2-3 months.
With occasional use (for example, with
discomfort after errors in the diet) take 15 ml once.
Dosage (volume) of the substance in the preparation
:
100 ml: aluminum hydroxide (in the form of a gel) 3.5 g, which corresponds to the content of aluminum oxide 2.3 g, magnesium hydroxide (in the form of a gel) 4 g
Information on technical characteristics, delivery set, country of manufacture "