Maalox - a bottle of 250 ml suspension, heartburn and pain in the stomach

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SKU
OTC10206259
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Category

Heartburn

Scope of the medicinal product

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Italy

Package quantity, pcs

one

Description

the white suspension is homogeneous after shaking.

Pharmacodynamics

Aluminum hydroxide and magnesium hydroxide neutralize free hydrochloric acid of gastric juice, without causing its secondary hypersecretion.

In addition, an increase in the pH of gastric juice while taking Maalox ® leads to a decrease in the activity of pepsin in the gastric juice.

The drug also has an adsorbent and enveloping effect, due to which the effect of damaging factors on the mucous membrane of the esophagus and stomach is reduced.

Pharmacokinetics

Magnesium hydroxide and aluminum hydroxide are considered topical antacids.

Due to low absorption, they do not have a systemic effect.

Name ENG

MAALOX

Clinical and pharmacological group

Antacid drug

ATX code

A02AX

Dosage

magnesium hydroxide (in the form of a gel) - 4.0 g, aluminum hydroxide (in the form of a gel) - 3.5 g,

in terms of aluminum oxide 2.3 g

Structure

100 ml of suspension contains:

active substances:

magnesium hydroxide (in the form of a gel) - 4.0 g, aluminum hydroxide (in the form of a gel) - 3.5 g,

in terms of aluminum oxide 2.3 g

auxiliary substances: hydrochloric acid 10% - 0.52815 g, citric

acid monohydrate - 0.0655 g, peppermint leaves oil - 0.0126 g, mannitol - 0.250

g, domiphene bromide - 0.00422 g, sodium saccharinate - 0.028 g, sorbitol 70% - 1.429 g,

hydrogen peroxide 30% - 0.065 g, purified water up to 100 ml.

Indications

Peptic ulcer and duodenal ulcer in the acute phase.

- Acute gastroduodenitis, chronic gastroduodenitis with normal or

increased secretory function in the acute phase.

- Hernia of the esophageal opening of the diaphragm, reflux esophagitis.

- Dyspeptic phenomena such as discomfort, gastralgia, heartburn (after

excessive use of ethanol, nicotine, coffee, taking medicinal

means, errors in the diet).

- Discomfort or pain in the epigastrium, heartburn, sour belching after errors in

diet, excessive consumption of alcohol, coffee, nicotine, etc.

Storage conditions and periods

At a temperature not higher than 25 degrees.

(do not freeze).

Expiration date: 3 years

after opening - 6 months

Contraindications

Severe renal failure.

- Hypersensitivity to active substances and other components

drug.

- Fructose intolerance (due to the presence of sorbitol in the preparation).

- Children and adolescents up to 15 years old.

- Hypophosphatemia.

Carefully

- Aluminum hydroxide can cause constipation, overdose of magnesium salts can

lead to a weakening of intestinal peristalsis

in patients from the group

increased risk (patients with renal impairment, elderly people)

taking high doses of the drug may cause or worsen bowel obstruction

and intestinal obstruction.

- Aluminum hydroxide is poorly absorbed in the gastrointestinal tract, therefore,

in patients with normal renal function, systemic exposure is rare.

Long-term treatment, the use of excessively high doses of the drug, or

the use of normal doses of the drug against the background of a low intake of phosphates with

food can lead to phosphate deficiency (due to the binding of aluminum with

phosphate), which is accompanied by increased bone resorption and

hypercalciuria with the risk of osteomalacia.

Treating patients at risk

development of phosphate deficiency or prolonged use of the drug should

exercise under medical supervision.

- With renal failure with prolonged use, an increase in

plasma concentrations of magnesium and aluminum.

In these patients with prolonged

the use of the drug in high doses may develop encephalopathy, dementia,

microcytic anemia or worsening dialysis-induced osteomalacia.

- In patients with porphyria on hemodialysis

during pregnancy and

breastfeeding (see the section Use during pregnancy and during breastfeeding

feeding ")

- With Alzheimer's disease

INN / Active ingredient

magnesium hydroxide (in the form of a gel)

aluminum hydroxide (gel)

Specifications

Category

Heartburn

Scope of the medicinal product

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Italy

Package quantity, pcs

one

Minimum age from

15 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Volume, ml.

250 ml

Brand name

Sanofi

The amount of the dosage form in the primary package

250 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antacid

Anatomical and therapeutic characteristics

A02AX Antacids, in combination with other drugs

Dosage form

Suspension for oral administration

Packaging

Cardboard box

The target audience

Children

Expiration date in days

912

Package weight, g

250

Mode of application

:

Inside.

Shake the bottle before use.

Adults and adolescents over 15 years old: 15 ml (1 tablespoon) 3-4 times a day after 1

2 hours after meals and at night.

The dose should not exceed 6 tablespoons per day.

When

reflux esophagitis, the drug is taken a short time after eating.

A course of treatment

should not exceed 2-3 months.

With occasional use (for example, with

discomfort after errors in the diet) take 15 ml once.

Dosage (volume) of the substance in the preparation

:

100 ml: aluminum hydroxide (in the form of a gel) 3.5 g, which corresponds to the content of aluminum oxide 2.3 g, magnesium hydroxide (in the form of a gel) 4 g

Information on technical characteristics, delivery set, country of manufacture "

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