Lyophilized lactobacillus culture Lactobacillus casei rhamnosus Doderleini | Lactozhinal vaginal capsules of 14 pieces

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In stock
SKU
BID468927
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Release form

Vaginal capsules
Release form

Vaginal capsules

Packing

14 pcs.

Pharmacological action

Lactobacillus casei is a species of gram-positive rod-shaped anaerobic non-spore forming bacteria.

Lactobacillus casei - normal obligate flora of the oral cavity, intestines, vulva and vagina of a person.

Pharmacotherapeutic group: eubiotic

ATX code: G01AX14

Pharmacological properties of

Lactobacillus casei, along with other types of lactobacilli (L. acidophilus, L. fermentum, L. cellobiosum and others), are present in the normal flora of the woman’s vulva. Vaginal colonization with live rods of L. casei rhamnosus Doderleini creates a similar physiological environment in the vagina. Strain L. casei rhamnosus Doderleini as part of Lactozhinal® has antagonistic activity against a wide range of pathogenic and opportunistic bacteria (including Staphylococcus spp., Proteus spp., enteropathogenic Escherichia coli), improves local metabolic processes and helps restore natural local immunity.

When a capsule of the Lactozhinal® preparation is inserted into the vagina, the gelatin shell of the capsule dissolves with the release of a lyophilized culture of live lactobacilli. In vitro, L. casei rhamnosus Doderleini has been shown to lower pH within a few hours. The indicated property of L. casei rhamnosus Doderleini with the introduction of the drug into the vagina helps to restore its natural microflora.

Lactobacillus deficiency is one of the important factors in the development of candidal vulvovaginitis. Lactobacilli are physiological antagonists of yeast fungi of the genus Candida due to the secretion of antifungal substances and competition for receptors on the vaginal epithelial cells (inhibit the attachment of Candida to vaginal epithelial cells, inhibit their growth and reproduction).

The results of a clinical study showed the efficacy of Lactozhinal® in restoring normal vaginal microflora and preventing recurrent vulvovaginal candidiasis after its use with antifungal therapy.

Indications

- Restoring normal vaginal microflora after antibiotic therapy of bacterial vaginosis

- in preparation for routine gynecological surgery for prenatal preparation of pregnant women at risk for bacterial vaginosis,

- prevention of recurrence of vulvovaginal candidiasis (vulvovaginal candidiasis) ) after local and / or systemic antifungal therapy.

Contraindications

- Hypersensitivity to the components of the drug.

- Vulvovaginal candidiasis ("thrush").

- Children under 18 years of age (efficacy and safety not established).

Use during pregnancy and lactation

The drug Lactozhinal® can be used during pregnancy and during breastfeeding.

Special instructions

After administration, the capsule dissolves, without staining laundry or smell.

The drug is intended for use in women over 18 years of age.

Effect on the ability to drive vehicles and mechanisms

The use of the drug LaktozhinalВ® does not affect the ability to drive vehicles and mechanisms.

Composition

Composition per capsule

Contents of the capsule:

Active ingredient:

Lyophilized culture of lactobacilli L. casei rhamnosus Doderleini at least 1x108 CFU of viable bacteria.

Excipients:

potato starch ~ 139.810 mg,

lactose monohydrate ~ 74.676 mg,

sodium glutamate ~ 15.345 mg,

sodium thiosulfate ~ 91.388 mg,

magnesium stearate 3.410 mg srdlp gel: srdlp.

Description

Transparent gelatin capsules size "0", filled with a powder of light yellow with a brownish tint.

Dosage and Administration

Dosage and Administration - intravaginally.

Insert the capsule deep into the vagina, by moistening it in a small amount of water to accelerate the dissolution of the drug.

Restoring normal vaginal microflora after antibiotic therapy of bacterial vaginosis: one capsule in the morning and evening for 7 days or one capsule daily for 14 days.

In preparation for planned gynecological operations, prenatal preparation of pregnant women at risk for bacterial vaginosis: one capsule in the morning and evening for 7 days or one capsule daily for 14 days as part of complex therapy.

Dosage regimen should be adjusted depending on the severity of the clinical effect.

Prevention of relapse of vulvovaginal candidiasis (including exacerbation of recurrent vulvovaginal candidiasis) after local and / or systemic antifungal therapy: 1 capsule per night. The duration of drug therapy is determined by the doctor. The course of treatment should not exceed more than 21 days. The question of conducting repeated courses is decided individually.

Side effects

Allergic reactions (including itching, burning, redness in the genital area, increased mucous discharge from the vagina).

Drug interaction

The use of the drug together with spermicidal agents is not recommended.

Possible simultaneous use with antibacterial, antiviral and immunomodulating drugs.

No clinically significant cases of interaction have been reported.

Overdose

No overdose has been reported.

Storage conditions

Do not store above 25 РC.

Keep out of the reach and sight of children.

Shelf life

3 years. Do not use after the expiration date.

Deystvuyushtee substance

Liofilizirovannaya kulytura Lactobacterin Lactobacillus casei rhamnosus Doderleini

Terms and conditions

without prescription

dosage form

capsules vaginal

Appointment

Appointment

Adults

bi'os industry, France

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