Lugol spray, 50g

The drug is applied topically 4-6 times a day to irrigate the mucous membrane of the mouth, pharynx, pharynx, spraying a spray with one press of the spray head. At the time of injection, it is recommended to hold your breath. Avoid contact with eyes. If this happens, the eyes should be flushed with plenty of water or sodium thiosulfate solution.

Spray for topical application 100 g

iodine 1 g

Excipients: potassium iodide 2 g, glycerol 94 g, purified water 3 g.

Hypersensitivity to iodine or other components of the drug.

Use with caution in patients with decompensated liver and kidney diseases, thyrotoxicosis, dermatitis herpetiformis.

pharmachologic effect

The main active ingredient is molecular iodine, which has an antiseptic and local irritating effect. Has a bactericidal effect against gram-negative and gram-positive flora, and also acts on pathogenic fungi (including yeast); Staphylococcus spp. more resistant to iodine, however, with prolonged use of the drug in 80% of cases, there is a suppression of staphylococcal flora; Pseudomonas aeruginosa is resistant to the action of the drug. When applied to extensive surfaces of the skin and mucous membranes, iodine has a resorptive effect: it participates in the synthesis of TK and T4. Iodide, which is part of potassium, improves the dissolution of iodine in water, and glycerol has a softening effect.

Pharmacokinetics

In the case of using the drug in recommended doses, the resorption of iodine through the skin and mucous membranes of the oral cavity is negligible. Upon contact with mucous membranes, it turns into iodides by 30%. If accidentally swallowed, iodine is rapidly absorbed. The adsorbed part penetrates well into tissues and organs, accumulates in the tissues of the thyroid gland. It is excreted by the kidneys (mainly), to a lesser extent with feces and with sweat. Penetrates into the milk of lactating women.

Side effect

Allergic reactions. With prolonged use - the phenomenon of 'iodism': rhinitis, urticaria, angioedema, salivation, lacrimation, acne. If this or any other side effect occurs during the use of the drug, you should consult your doctor.

Application during pregnancy and lactation

The use of the drug during pregnancy is not recommended. Application during breastfeeding is possible if the expected benefit to the mother outweighs the potential risk to the child. It is necessary to consult a doctor.

Application for violations of liver function

Use with caution in patients with decompensated liver disease.

Application for impaired renal function

Use with caution in patients with decompensated kidney disease.

special instructions

Sunlight and temperatures above 40 ? C accelerate the decomposition of active iodine.

Overdose

Symptoms: irritate the upper respiratory tract (burn, laryngobronchospasm); if ingested - the mucous membranes of the gastrointestinal tract, the development of hemolysis, hemoglobinuria; lethal dose - about 3 g (about 300 ml of the drug). Treatment: gastric lavage with 0.5% sodium thiosulfate solution, sodium bicarbonate solutions, sodium thiosulfate 30% is injected intravenously - up to 300 ml.

Drug interactions

Iodine is inactivated by sodium thiosulfate. The iodine contained in the preparation oxidizes metals, which can lead to damage to metal objects. Pharmaceutically incompatible with essential oils, ammonia solutions. An alkaline or acidic environment, the presence of fat, pus, blood weaken the antiseptic activity.