Loratadin tablets 10mg, No. 30
Expiration Date: 05/2027
Russian Pharmacy name:
Лоратадин таблетки 10мг, №30
Seasonal and perennial allergic rhinitis,
conjunctivitis,
acute urticaria and angioedema,
symptoms of histaminergic caused by the use of histaminoliberates (pseudo-allergic syndromes),
allergic reactions to insect bites,
complex treatment of itchy dermatoses (contact allergic dermatitis, chronic eczema).
Inside, regardless of the time of the meal.
Inside for adults and children over 12 years old, as well as with a body weight of more than 30 kg - 10 mg 1 time / day.
Children from 2 to 12 years old with a body weight of less than 30 kg - 5 mg 1 time / day.
Active substance:
loratadine
Pregnancy,
lactation,
children under 2 years old,
hypersensitivity to loratadine.
pharmachologic effect
Blocker of histamine H1 receptors. It has antiallergic, antipruritic, antiexudative effect. Reduces capillary permeability, prevents the development of tissue edema, reduces the increased contractile activity of smooth muscles, due to the action of histamine.
Indications
Seasonal and perennial allergic rhinitis,
conjunctivitis,
acute urticaria and angioedema,
symptoms of histaminergic caused by the use of histaminoliberates (pseudo-allergic syndromes),
allergic reactions to insect bites,
complex treatment of itchy dermatoses (contact allergic dermatitis, chronic eczema).
Dosage regimen
Inside for adults and children over 12 years old, as well as with a body weight of more than 30 kg - 10 mg 1 time / day.
Children from 2 to 12 years old with a body weight of less than 30 kg - 5 mg 1 time / day.
Side effect
From the digestive system: rarely - dry mouth, nausea, vomiting, gastritis; in some cases - liver dysfunction.
From the side of the central nervous system: rarely - increased fatigue, headache, irritability (in children).
From the side of the cardiovascular system: rarely - tachycardia.
Allergic reactions: rarely - skin rash; in isolated cases - anaphylactic reactions.
Dermatological reactions: in some cases - alopecia.
Contraindications for use
Pregnancy,
lactation,
children under 2 years old,
hypersensitivity to loratadine.
Application during pregnancy and lactation
Loratadine should not be used during pregnancy and lactation.
In experimental studies on animals, loratadine in medium doses did not have a negative effect on the fetus; when administered in high doses, some fetotoxic effects were observed.
Application for violations of liver function
Patients with impaired renal or hepatic function require a dosage adjustment.
Application for impaired renal function
Patients with impaired renal or hepatic function require a dosage adjustment. Use in children Contraindicated in children under 2 years of age.
special instructions
When using loratadine, the development of seizures cannot be completely ruled out, especially in predisposed patients.
Patients with impaired renal or hepatic function require a dosage adjustment.
Drug interactions
With the simultaneous use of loratadine with drugs that inhibit the isoenzymes CYP3A4 and CYP2D6 or are metabolized in the liver with their participation (including cimetidine, erythromycin, ketoconazole, quinidine, fluconazole, fluoxetine), a change in the plasma concentration of loratadine and / or these drugs.
Microsomal oxidation inducers (phenytoin, ethanol, barbiturates, zixorin, rifampicin, phenylbutazone, tricyclic antidepressants) reduce the effectiveness.