Ligfol (1 dose) bottle 1 ml

DESCRIPTION

Ligfol is a drug for agricultural, domestic animals and fur-bearing animals to increase the general resistance and adapt the body's defenses to adverse effects. Dosage form: injection solution. In appearance, the drug is a dark brown liquid.

COMPOSITION

The drug in 1 ml contains as an active ingredient the butanol fraction of humic acids - 6 mg and auxiliary substances: sodium diphosphate - 5.5 mg, sodium chloride - 3.0 mg and water for injection - up to 1 ml.

PHARMACOLOGICAL PROPERTIES

Ligfol belongs to the drugs of the group of immunomodulators.

The pharmacological properties of Ligfol are based on the ability of humic acids to stimulate immune-antioxidant mechanisms, including binding free radicals, increasing the activity of phagocytes, which increases the resistance of the animal body to unfavorable factors.

According to the degree of impact on the body, Ligfol belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), does not have local irritating, embryotoxic and teratogenic properties.

Ligfol is compatible with known drugs for specific and symptomatic therapy and feed additives. Due to the possible weakening of the degree of anesthesia, the interval between the introduction of Ligfol and the anesthetic agent should be at least 5 hours.

INDICATIONS

Ligfol is prescribed to farm animals, dogs, cats and fur animals for immunocorrection in pathological conditions that are caused or accompanied by secondary immune deficiency, caused, in particular, by stress maladjustment of the animal's body.

APPLICATION

Ligfol is administered intramuscularly to the animal in the following single doses: horses and cows - 5 ml; pigs - 3 ml; sheep, calves, foals, dogs and cats weighing over 10 kg - 1 ml; piglets, lambs - 0.5 ml; fur animals, cats and dogs weighing up to 10 kg - 0.1 ml / kg of animal weight.

For the prevention of postpartum complications (retention of the placenta, subinvolution of the uterus, postpartum endometritis, mastitis), the drug is used: for cows, sows and sheep twice - the first injection 10-20 days before the expected birth, the second injection 2-3 hours after birth; mares in the last 2 months of fertility once a week and once in 2-3 hours after giving birth.

To stimulate the reproductive functions of females, the drug is used: for cows, mares, sows, sheep, once, 1-3 days before insemination; for fur animals twice - the first injection 30 days before rutting, the second one 30 days before whelping; dogs and cats three times - once every three days 10 days before mating.

To increase the resistance of young animals, the drug is used: for calves 4 times - on the 5th, 15th, 20th and 25th day of life; foals 5 times - on the 15th, 20th, 25th, 60th, 90th day of life; to piglets twice - 3 days before weaning and 10-15 days after weaning; lambs twice - on the 7th and 14th days of life, then once a month until 6 months of age.

To increase weight gain in cattle and fattening pigs, the drug is used once a month during the entire production cycle.

As part of the complex therapy of diseases of the liver and pancreas, as well as to reduce intoxication from the use of hepatotoxic drugs, Ligfol is used for farm animals, dogs, cats and fur animals 6 times - 1 time in 3 days.

In surgical practice, Ligfol is used before surgery to improve the tolerance of anesthesia and adapt the animal to stress once, no later than 5 days before the intended surgical intervention.

In order to prevent postoperative complications, accelerate the process of tissue regeneration and shorten the recovery period, Ligfol is used: the first injection immediately after the operation, the second injection after 24 hours, and then 5 injections with an interval of 7 days. In addition, in the course of treatment, local irrigation with Ligfol of the surgical wound is carried out once a day until signs of stable tissue regeneration appear.

For diseases of viral etiology in farm animals, dogs, cats and fur animals, Ligfol is used in combination with specific therapy after the first signs of the disease appear twice with an interval of 24 hours.

If necessary, the course of application is extended to 20-30 days, with an interval between injections of 5 days.

For horse helminthiasis, Ligfol is used in combination with specific therapy twice: the first injection 48-72 hours before deworming, the second injection on the day of deworming. If signs of intoxication appear after the use of an anthelmintic, Ligfol is additionally administered on the 5th, 15th and 45th day after deworming.

For the treatment of horses in the early stages of acute obstructive bronchitis, the drug is used as part of complex therapy 4 times - on the 2nd, 5th, 10th and 20th days after the first symptoms of the disease appear.

To quickly restore the physiological state of sports horses, Ligfol is used: once, 3 days before the proposed event.

For babesiosis (piroplasmosis) in horses and dogs, the drug is used in combination with specific therapy: 1st injection 30 minutes before the introduction of the antiprotozoal drug, then 4-6 injections with an interval of 3 days.

To stabilize and control the growth of immuno- and hormone-dependent tumors in dogs and cats, Ligfol is used as part of complex therapy in two stages - I stage 5-7 injections with an interval of 3 days, then II stage - 5 injections with an interval of 7 days. If necessary, repeat the course of the drug in a month.

Violations of the drug use regimen should be avoided, as this can lead to a decrease in its effectiveness. If one dose is missed, the drug should be administered as soon as possible in the same dose.

CONTRAINDICATIONS

A contraindication for use is the increased individual sensitivity of the animal to the components of the drug, including the history.

OVERDOSE

Overdose symptoms have not been established.

SIDE EFFECTS

In rare cases, with the first administration of Ligfol, a slight short-term increase in temperature is possible in an animal. Cancellation of the drug and the use of antipyretic drugs is not required.

When using the drug in accordance with this instruction, side effects and complications, as a rule, are not observed. In rare cases, slight pain is possible at the injection site, which quickly disappears without the use of drugs.

Slaughter of animals for meat is allowed no earlier than 6 days after the last application of Ligfol. In the event of the forced slaughter of animals before the established deadline, the meat can be used as feed for fur animals. Milk of dairy animals obtained during the treatment period and within 6 days after the last use of the drug should not be used for food purposes, such milk after boiling can be used in animal feed.

PRECAUTIONS

When carrying out therapeutic and prophylactic measures with the use of Ligfol, the general rules of personal hygiene and safety measures provided for when working with medicines should be observed. It is forbidden to use empty containers from under the medicinal product for household purposes, it must be disposed of with household waste.

FIRST AID MEASURES

In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they should be rinsed with plenty of water. People with hypersensitivity to the components of the drug should avoid direct contact with Ligfol. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for use of the drug or a label with you).

STORAGE

Store the drug in the manufacturer's closed packaging, separately from food and feed, in a dry, dark place at a temperature of 15 В° C to 25 В° C. The shelf life of the drug, subject to storage conditions in the manufacturer's closed packaging, is 2 years from the date of production after the first opening of the package, the drug should be used within 24 hours.

PACKING

Vials with a capacity of 1 ml are packed in 4 pieces in polymer cases with a cardboard insert.

Specifications

KolVUP

4

Manufacturer

Ligpharm

Temperature regime

from +15 to +25

Teaser

a drug for agricultural, domestic animals and fur animals to increase the general resistance and adaptation of the body's defenses to adverse effects