Libeksin flour syrup for children 2%, 125 ml bottle

• Acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous, difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis) and mucus (inflammatory diseases of the middle ear, nose and its paranasal sinuses - rhinitis, otitis media, sinusitis).

• Preparing the patient for bronchoscopy or bronchography.

Inside.
One scoop of syrup (5 ml) contains 100 mg of carbocysteine. Children aged 2 to 5 years: One scoop (5 ml) 2 times a day (200 mg per day).
Children over 5 years of age: One scoop (5 ml) 3 times a day (300 mg per day). Treatment should not be continued for more than 8 days without consulting a doctor.

100 ml of syrup contains:

Active substance:

Carbocisteine ??2,000 g

Excipients:

Sucrose 70,000 g

Methyl parahydroxybenzoate 0.150 g

Vanillin 0.050 g

Crimson dye (Ponso 4R)

(cochineal red A (E 124)) 0.005 g

Raspberry flavor 1.0 ml

Cherry flavor 0.5 ml

Sodium hydroxide qs to pH 6.1 - 6.3

Purified water qs up to 100 ml

One scoop of syrup (5 ml) contains 100 mg carbocysteine, 3.5 g sucrose and 13 mg sodium.

• Hypersensitivity to carbocisteine ??or other components of the drug.

• Peptic ulcer and duodenal ulcer in the acute stage.

• Chronic glomerulonephritis (in the acute phase), cystitis.

• Pregnancy.

• Children up to age 2 years.

Carefully

History of gastric ulcer and duodenal ulcer, lactation period.

Trade name of the drug : Libexin MukoЃ.

International non-proprietary name : carbocisteine.

Dosage form : syrup for children.

Composition

100 ml of syrup contains:

Active substance:

Carbocisteine ??2,000 g

Excipients:

Sucrose 70,000 g

Methyl parahydroxybenzoate 0.150 g

Vanillin 0.050 g

Crimson dye (Ponso 4R)

(cochineal red A (E 124)) 0.005 g

Raspberry flavor 1.0 ml

Cherry flavor 0.5 ml

Sodium hydroxide qs to pH 6.1 - 6.3

Purified water qs up to 100 ml

One scoop of syrup (5 ml) contains 100 mg carbocysteine, 3.5 g sucrose and 13 mg sodium.

Description

Syrupy liquid of red color with the smell of raspberries and cherries.

Pharmacotherapeutic group

Expectorant mucolytic agent.

ATX code : R05CB03

pharmachologic effect

Carbocisteine, being a mucolytic, acts on the gel phase of endobronchial secretion, breaking the disulfide bridges of glycoproteins and, thus, decreasing the viscosity and increasing the elasticity of the secretion. Carbocisteine ??activates sial transferase - an enzyme of the goblet cells of the bronchial mucosa, normalizes the quantitative ratio of acidic and neutral sialomucins, promotes the regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliated epithelium, restores the secretion of immunologically active IgA (specific protection), improves mucociliary clearance.

Pharmacokinetics

Carbocisteine ??is rapidly absorbed after oral administration, reaching a maximum serum level after 2 hours. Bioavailability is low (less than 10% of the dose taken) as a result of possible rapid passage through the liver. The half-life is about 2 hours. It is excreted mainly by the kidneys along with metabolites.

Indications for use

• Acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous, difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis) and mucus (inflammatory diseases of the middle ear, nose and its paranasal sinuses - rhinitis, otitis media, sinusitis).

• Preparing the patient for bronchoscopy or bronchography.

Contraindications

• Hypersensitivity to carbocisteine ??or other components of the drug.

• Peptic ulcer and duodenal ulcer in the acute stage.

• Chronic glomerulonephritis (in the acute phase), cystitis.

• Pregnancy.

• Children up to age 2 years.

Carefully

History of gastric ulcer and duodenal ulcer, lactation period.

Method of administration and dosage

Inside.
One scoop of syrup (5 ml) contains 100 mg of carbocysteine. Children aged 2 to 5 years: One scoop (5 ml) 2 times a day (200 mg per day).
Children over 5 years of age: One scoop (5 ml) 3 times a day (300 mg per day). Treatment should not be continued for more than 8 days without consulting a doctor.

Side effect

From the gastrointestinal tract: sometimes there is nausea, vomiting, diarrhea, epigastric pain, gastrointestinal bleeding. Allergic reactions: itching, urticaria, exanthema, angioedema.
Others: dizziness, weakness, malaise.

Re-encoding

Symptoms: gastralgia, nausea, diarrhea. Treatment is symptomatic.

Interaction with other medicinal products

Increases the effectiveness of glucocorticosteroid and antibacterial therapy for inflammatory diseases of the upper and lower respiratory tract. Potentiates the bronchodilator effect of theophylline. The activity of carbocisteine ??is weakened by antitussives and m-anticholinergic drugs.

special instructions

When prescribing Libeksin Muko to patients with diabetes mellitus or patients on a low-carbohydrate diet, the sucrose content of 3.5 g per scoop should be taken into account.

Forms of issue

Syrup for children 20 mg / ml.
125 ml or 200 ml in a colorless glass bottle (type III), closed with a screw cap with a first opening control. 1 bottle with a measuring spoon and instructions for use in a cardboard box.

Storage conditions

Store at a temperature not exceeding 25 ? C. Keep out of the reach of children.

Shelf life

3 years.
Do not use after the expiration date.

Conditions of dispensing from pharmacies

Without recipe.