Legalon caps. 70 mg No. 60

pharmachologic effect

Legalon interacts with free radicals in the liver and converts them into less toxic compounds, interrupting the process of lipid peroxidation, and prevents the destruction of cellular structures.

In damaged hepatocytes, it stimulates the synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA polymerase A), stabilizes cell membranes, prevents the loss of cell components (transaminases), accelerates the regeneration of liver cells.

It inhibits the penetration of some hepatotoxic substances into the cell.

Indications

Toxic (including medicinal) liver damage, alcoholism, intoxication with halogenated hydrocarbons, heavy metal compounds, chronic inflammatory liver diseases, liver cirrhosis (supportive therapy).

Contraindications

Hypersensitivity

special instructions

It is recommended to consult a specialist before use.

Structure

1 capsule contains: milk thistle spotted fruit extract dry (18-22: 1) - 86.5 - 93.35 mg, equivalent to 70 mg of silymarin (DNPH), equivalent to 54.1 mg of silymarin (HPLC / HermF) calculated as silibinin ...

Method of administration and dosage

Inside, after meals, without chewing and drinking a small amount of liquid.

For initial treatment and in severe cases - 2 tablets or 1 capsule 3 times a day

maintenance dose - 1 tablet 3 times a day or 1 capsule 2 times a day.

Side effects

Diarrhea (rare)

Storage conditions

In a dark place at a temperature not exceeding 30 ° C.

Shelf life

5 years

Active substance

Milk thistle fruit extract

Name ENG

LEGALON 70

Clinical and pharmacological group

Hepatoprotector

ATX code

Silymarin

Dosage

70mg

Structure

1 capsule contains: milk thistle spotted fruit extract dry (18-22: 1) - 86.5 - 93.35 mg, equivalent to 70 mg of silymarin (DNPH), equivalent to 54.1 mg of silymarin (HPLC / HermF) calculated as silibinin ...

Indications

Toxic (including medicinal) liver damage, alcoholism, intoxication with halogenated hydrocarbons, heavy metal compounds, chronic inflammatory liver diseases, liver cirrhosis (supportive therapy).

Storage conditions and periods

In a dark place at a temperature not exceeding 30 degrees.

Expiration date: 5 years

INN / Active ingredient

Milk thistle fruit extract

Contraindications

hypersensitivity to drug components.

Specifications

Category

Hepatoprotectors

Scope of the drug

Gastrointestinal tract

Release form

Capsules

Manufacturer country

Germany

Package quantity, pcs

60

Scope of application

Hepatology

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

MADAUS

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Hepatoprotective agent

Anatomical and therapeutic characteristics

A05BA03 Silymarin

Dosage form

Capsules

Expiration date in days

1826

The target audience

Adult

Package weight, g

230

Mode of application

:

Inside, after meals, without chewing and drinking a small amount of liquid.

For initial treatment and in severe cases - 2 tablets or 1 capsule 3 times a day

maintenance dose - 1 tablet 3 times a day or 1 capsule 2 times a day.

Dosage (volume) of the substance in the preparation

:

1 capsule contains: dry extract of milk thistle fruit (36-44: 1) 86.5-93.35 mg, which corresponds to the content of silymarin [DNPH] 70 mg, which corresponds to the content of silymarin [HPLC] in terms of silybinin 54.1 mg