Legalon 140 capsules 140 mg No. 30

pharmachologic effect

Legalon interacts with free radicals in the liver and converts them into less toxic compounds, interrupting the process of lipid peroxidation, and prevents the destruction of cellular structures.

In damaged hepatocytes, it stimulates the synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA polymerase A), stabilizes cell membranes, prevents the loss of cell components (transaminases), accelerates the regeneration of liver cells.

It inhibits the penetration of some hepatotoxic substances into the cell.

Indications

Toxic liver damage:

- Alcoholism.

- Intoxication with halogenated hydrocarbons.

- Compounds of heavy metals.

- Medicinal liver damage.

Contraindications

Hypersensitivity to drug components.

Application during pregnancy and lactation

It is not recommended to use the drug during pregnancy and breastfeeding.

special instructions

It is recommended to consult a specialist before use.

Structure

1 capsule contains: Milk thistle fruit extract dry (36-44: 1) - 173.0 - 186.7 mg, Equivalent to 140 mg of silymarin (DNPH), Equivalent to 108.2 mg of silymarin (HPLC / HermF) calculated as silybinin.

Method of administration and dosage

Inside, after meals with a little water.

1 capsule 3 times a day.

Maintenance dose - 1 capsule 2 times a day.

Side effects

Allergic reactions.

Rarely a laxative effect.

Drug interactions

Not described.

Storage conditions

Store at a temperature not exceeding 30C.

Shelf life

5 years.

Active substance

Milk thistle fruit extract

Name ENG

LEGALON 70

Clinical and pharmacological group

Hepatoprotector

ATX code

Silymarin

Dosage

140mg

Structure

1 capsule contains: Milk thistle fruit extract dry (36-44: 1) - 173.0 - 186.7 mg, Equivalent to 140 mg of silymarin (DNPH), Equivalent to 108.2 mg of silymarin (HPLC / HermF) calculated as silybinin.

Indications

Toxic liver damage: - Alcoholism. - Intoxication with halogenated hydrocarbons. - Compounds of heavy metals. - Medicinal liver damage.

Storage conditions and periods

In a dark place at a temperature not exceeding 30 degrees.

Expiration date: 5 years

Contraindications

hypersensitivity to drug components.

INN / Active ingredient

Milk thistle fruit extract

Specifications

Category

Hepatoprotectors

Scope of the drug

Gastrointestinal tract

Release form

Capsules

Manufacturer country

Germany

Package quantity, pcs

thirty

Scope of application

Hepatology

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

MADAUS

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Hepatoprotective agent

Anatomical and therapeutic characteristics

A05BA03 Silymarin

Dosage form

Capsules

The target audience

Adult

Expiration date in days

1826

Package weight, g

twenty

Mode of application

:

Inside, after meals with a little water.

1 capsule 3 times a day. < br> Maintenance dose - 1 capsule 2 times a day.

Dosage (volume) of the substance in the preparation

:

173-188.7 mg dry extract of milk thistle fruit, or 140 mg silymarin, calculated from silibinin