Lavacol powder for preparation of oral solution 14g, No. 15

Special Price $18.43 Regular Price $27.00
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SKU
BIDL3179147
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Expiration Date: 05/2027

Russian Pharmacy name:

Лавакол порошок для приготовления р-ра для приема внутрь 14г, №15

Lavacol powder for preparation of oral solution 14g, No. 15

  • preparation for endoscopic or X-ray examination of the colon, as well as for surgical interventions requiring the absence of contents in the intestine;

  • symptomatic treatment of constipation in adults.

The drug is taken orally. The drug can only be used in adult patients .

Preparation for endoscopic or X-ray examination of the colon, as well as for surgical interventions

The drug is taken on an empty stomach. The contents of the package (14 g) are dissolved in 200-250 ml of water immediately before use.

When prescribing a procedure (research or surgery) for the first half of the day (up to 12 hours), the solution should be taken the night before - at the rate of 15 packages (approximately 200-250 ml each) with an interval of 20 minutes. The recommended hours of taking the drug are from 5 pm to 10 pm.

If the procedure is scheduled for the second half of the day (after 12 hours), the intake of the solution should be divided into 2 stages (the night before, the patient takes the solution at the rate of 10 bags and 5 bags in the morning). Recommended reception hours: on the eve of the procedure 19-22 hours (10 packages), in the morning before the procedure from 6 to 9 hours (5 packages).

The drug must be completed 3-4 hours before the procedure. In the process of taking and after it, only liquid food is consumed. After 22 hours, food intake is not indicated.

Symptomatic treatment of constipation in adults

The contents of each packet should be dissolved in a glass of water immediately before taking. 1 sachet in the morning or 1 sachet in the morning and in the evening in case of taking 2 packages a day The daily dosage must be adapted according to the clinical response and can range from 1 sachet every day to 2 sachets per day.

The effect of taking the drug is expressed within 24-28 hours after taking it. The recommended course of treatment is 1 month.

The maintenance of the effect after the restoration of normal bowel function should be carried out with an active lifestyle and a diet rich in plant fiber. If symptoms of constipation persist for more than 1 month, a second extended diagnostic examination should be performed.

Powder for the preparation of a solution for oral administration, white or white with a yellowish or grayish tint; the prepared solution is a colorless or slightly colored liquid, slight opalescence is allowed.

1 pack.

Active ingredient: macrogol 4000 (polyethylene glycol 4000) - 12 g

Excipients: sodium sulfate (sodium sulfate) - 1 g, sodium bicarbonate (sodium bicarbonate) - 0.6 g, sodium chloride - 0.2 g, potassium chloride - 0.2 g.

  • hypersensitivity to macrogol or any of the excipients that make up the drug;

  • dehydration;

  • chronic heart failure;

  • stomach ulcer;

  • intestinal obstruction;

  • perforation or risk of perforation of the intestinal wall;

  • severe inflammatory bowel disease;

  • violation of gastric emptying (including gastroparesis);

  • age up to 18 years (efficacy and safety have not been established).

With care: ulcerative colitis, patients with impaired swallowing reflex, reflux esophagitis, depression of consciousness, impaired renal function, tendency to develop water-electrolyte imbalance, neurological disorders, impaired motor functions, tendency to aspiration, pregnancy, old age.

Clinical and pharmacological group: Laxative drug with osmotic properties

Pharmaco-therapeutic group: Laxative

pharmachologic effect

Osmotic laxative. A high-molecular substance, which is long linear polymers that, using hydrogen bonds, are able to hold water molecules. Increases osmotic pressure and volume of fluid contained in the intestine, enhancing peristalsis. Increases the volume of chyme, prevents the loss of electrolytes with feces. Restores the evacuation reflex, does not change the pH of the chyme.

The action of the drug is based on a combination of a high molecular weight polymer with an isotonic solution of electrolytes. Macrogol prevents the absorption of water from the stomach and intestines and promotes the accelerated evacuation of intestinal contents through frequent bowel movements. The electrolytes contained in the preparation prevent the disruption of the body's water-electrolyte balance.

Pharmacokinetics

Pharmacokinetic studies confirm the absence of absorption and metabolism of macrogol when taken orally.

Indications

  • preparation for endoscopic or X-ray examination of the colon, as well as for surgical interventions requiring the absence of contents in the intestine;

  • symptomatic treatment of constipation in adults.

Dosage regimen

The drug is taken orally. The drug can only be used in adult patients .

Preparation for endoscopic or X-ray examination of the colon, as well as for surgical interventions

The drug is taken on an empty stomach. The contents of the package (14 g) are dissolved in 200-250 ml of water immediately before use.

When prescribing a procedure (research or surgery) for the first half of the day (up to 12 hours), the solution should be taken the night before - at the rate of 15 packages (approximately 200-250 ml each) with an interval of 20 minutes. The recommended hours of taking the drug are from 5 pm to 10 pm.

If the procedure is scheduled for the second half of the day (after 12 hours), the intake of the solution should be divided into 2 stages (the night before, the patient takes the solution at the rate of 10 bags and 5 bags in the morning). Recommended reception hours: on the eve of the procedure 19-22 hours (10 packages), in the morning before the procedure from 6 to 9 hours (5 packages).

The drug must be completed 3-4 hours before the procedure. In the process of taking and after it, only liquid food is consumed. After 22 hours, food intake is not indicated.

Symptomatic treatment of constipation in adults

The contents of each packet should be dissolved in a glass of water immediately before taking. 1 sachet in the morning or 1 sachet in the morning and in the evening in case of taking 2 packages a day The daily dosage must be adapted according to the clinical response and can range from 1 sachet every day to 2 sachets per day.

The effect of taking the drug is expressed within 24-28 hours after taking it. The recommended course of treatment is 1 month.

The maintenance of the effect after the restoration of normal bowel function should be carried out with an active lifestyle and a diet rich in plant fiber. If symptoms of constipation persist for more than 1 month, a second extended diagnostic examination should be performed.

Side effect

From the digestive system: a feeling of stretching of the anterior abdominal wall, abdominal pain, nausea, diarrhea, vomiting, strong urge to defecate, fecal incontinence, irritation of the perianal region, flatulence.

Allergic reactions: urticaria, pruritus, skin rash, swelling of the face, Quincke's edema, anaphylactic shock, fulminant and acute pulmonary edema.

If any of the side effects indicated in the instructions are aggravated or any other side effects not indicated in the instructions are noted, the patient should inform the doctor about it.

Contraindications for use

  • hypersensitivity to macrogol or any of the excipients that make up the drug;

  • dehydration;

  • chronic heart failure;

  • stomach ulcer;

  • intestinal obstruction;

  • perforation or risk of perforation of the intestinal wall;

  • severe inflammatory bowel disease;

  • violation of gastric emptying (including gastroparesis);

  • age up to 18 years (efficacy and safety have not been established).

With care: ulcerative colitis, patients with impaired swallowing reflex, reflux esophagitis, depression of consciousness, impaired renal function, tendency to develop water-electrolyte imbalance, neurological disorders, impaired motor functions, tendency to aspiration, pregnancy, old age.

Application during pregnancy and lactation

The use of the drug during pregnancy is possible if the expected benefit to the mother outweighs the potential risk to the fetus (due to insufficient data to assess the effect of macrogol on the fetus).

Since macrogol is not absorbed from the gastrointestinal tract, the use of the drug during breastfeeding is possible in consultation with the attending physician.

Application for impaired renal function

The drug should be used with caution in case of impaired renal function.

Application in children

The use of the drug under the age of 18 is contraindicated (efficacy and safety have not been established).

Use in elderly patients

The drug should be used with caution in elderly patients.

special instructions

Elderly patients with various concomitant diseases are recommended to use the drug under medical supervision.

The patient should be warned about the need to inform the doctor about all simultaneously used drugs.

If diarrhea develops, special control and monitoring of the electrolyte composition of the blood is necessary in patients prone to the development of electrolyte disturbances.

It is recommended to use the drug with caution in patients with ulcerative colitis due to the high risk of perforation.

Influence on the ability to drive vehicles and mechanisms

Given the possibility of adverse reactions, care should be taken when driving and operating machinery.

Overdose

Exceeding the dose can lead to a violation of the water-electrolyte balance, the development of diarrhea, which, as a rule, stops on its own 1-2 days after the drug is discontinued.

Drug interactions

Diarrhea caused by the use of LavacolЃ can lead to impaired absorption of other drugs taken simultaneously. In the case of simultaneous administration of the drug LavacolЃ with other drugs, it is recommended to prescribe it 2 hours after taking them.

The simultaneous intake of macrogol and digoxin leads to a decrease in the degree of absorption of the latter in the intestine.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 ? C.

Shelf life of the drug

The shelf life is 5 years.

Terms of sale

The drug is dispensed without a prescription.

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