Lactobacilli acidophilus, Bifidobacteria BB12 | Linex Forte capsules 14 pcs.

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SKU
BID475762
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Release form

p.
Release form

p.

Packing

14 pieces.

Pharmacological action

PHARMACOTHERAPEUTIC GROUP

Eubiotic. ATX Code: A07FA51

PHARMACOLOGICAL PROPERTIES

Pharmacodynamics

Linex® Forte normalizes intestinal microflora. One capsule of Linex Forte contains lactic acid bacteria (Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. Lactis (BB-12)), each capsule contains 109 colony forming units of live lyophilized lactic acid bacteria. Living lactic acid bacteria are a normal component of the natural intestinal microflora. The main functions of lactic acid bacteria:

protective: synthesis of substances with antibacterial activity

enzyme-producing: hydrolysis of fiber, proteins, fats, starch, deconjugation of bile acids

synthetic: synthesis of vitamins B, C, K, amino acids, organic acids, etc. Lactic acid bacteria LA-5 and BB-12 inhibit the growth of pathogenic bacteria by: lowering the pH in the intestines (the result of the ability of LA-5 to synthesize lactic acid and BB-12 to synthesize acetic and succinic acids in addition to lactic acid)

produce metabolites that are toxic action against pathogenic bacteria (H2O2 formation)

formation of antimicrobial agents, bacteriocins (LA-5 secretes acidocin, a broad-spectrum bacteriocin that inhibits the growth of bacteria and fungi)

competitors and with pathogenic bacteria for nutrients

interactions with adhesion receptors, thereby preventing the colonization of other potentially pathogenic microorganisms.

Pharmacokinetics

Lactic acid bacteria such as LA-5 and BB-12, act directly in the gastrointestinal tract, when taken orally, the drug is not subjected to systemic absorption. Standard pharmacokinetic studies are therefore not applicable. The resistance of LA-5 and BB-12 to the effects of gastric juice and bile allows strains to survive in large numbers when passing through the stomach and duodenum. Both strains attach to the intestinal mucosa. Like other microorganisms, they are gradually excreted from the gastrointestinal tract by motility and defecation.

Indications

Treatment and prevention of intestinal dysbiosis.

Dysbacteriosis of the intestine is manifested by the following symptoms: diarrhea (diarrhea), dyspepsia (indigestion), constipation, flatulence (bloating), nausea, belching, vomiting, abdominal pain, allergic skin reactions are possible.

Contraindications

- hypersensitivity to the components of the drug

- hereditary fructose intolerance, deficiency of sucrose, isomaltase or glucose-galactose malabsorption.

CAUTION

Caution for diabetes mellitus (simple sugars included), deficiency of the immune system (eg, HIV infection). Diarrhea in children under 6 years of age must be treated under medical supervision.

Use during pregnancy and lactation

Due to the lack of data on use in pregnant women, it is not recommended to use Linex Forte capsules during pregnancy and lactation without first consulting a doctor.

When prescribing a drug for the treatment of acute diarrhea during pregnancy and lactation, the supervision of a doctor is necessary.

Special instructions

Do not drink LinexВ® Forte with hot drinks and take with alcohol.

You should consult your doctor before taking the drug if you have:

- body temperature above 38 РC

- traces of blood or mucus in the stool

- diarrhea lasts more than two days and is accompanied by acute abdominal pain, dehydration and weight loss

- chronic diseases - diabetes mellitus, HIV infection.

In the treatment of diarrhea, compensation for lost fluid and electrolytes is necessary.

Composition

1 capsule contains:

Active ingredient:

powder Probio-tech AB Blend 64 (Probio-tecΠAB Blend 64) - 60,000 mg (powder contains active ingredients: Lactobacillus acidophilus (LA-5) - 13.8 mg and Bifidobacterium animalis subsp. lactis (BB-12) - 4.2 mg

auxiliary components:

anhydrous dextrose - 29.1 mg, microcrystalline cellulose - 6 mg, potato starch 6 mg, magnesium stearate 0.9 mg).

Excipients:

Beneo Synergy 1 (BeneoΠSynergy 1) - 171,500 mg (powder contains 90-94% inulin and 6-10% oligofructose (dextrose + fructose + sucrose)) magnesium stearate - 3,500 mg.

Composition of the capsule body:

hypromellose - 33.149 mg, titanium dioxide (E 171) - 0.691 mg. The composition of the capsule cap: hypromellose - 22.080 mg, dye of titanium dioxide (E 171) - 0.240 mg, dye of iron oxide yellow (E 172) - 0.240 mg.

Dosage and administration

Linex® Forte Capsules should preferably be taken with or after meals with a small amount of liquid.

Adults and teenagers over 12 years of age: 1 capsule 1-3 times a day.

Children from 2 to 12 years: 1 capsule 1-2 times a day.

Newborns and children up to 2 years: 1 capsule 1 time per day.

Diarrhea in children under 6 years of age must be treated under medical supervision.

When prescribing Linex® Forte to children and patients who cannot swallow an entire capsule, it must be opened, pour the contents into a spoon and mix with a small amount of liquid.

The duration of treatment depends on the cause of the development of dysbiosis and the individual characteristics of the body. Linex® Forte can be taken until the symptoms of dysbiosis disappear.

Do not exceed recommended daily doses of the drug.

Side effects

The drug is well tolerated. There are no reports of adverse effects, but hypersensitivity reactions may be noted.

Drug Interactions

There was no adverse interaction with other drugs.

With the simultaneous use of antibiotics, the recommended interval between taking the drug (antibiotic) and Linex Forte capsules is 3 hours.

Overdose

There are no symptoms of overdose.

Storage conditions

Do not store above 25 РC. Keep out of reach of children.

Shelf life

2 years.

Active ingredient

Lactobacillus acidophilus, Bifidobacteria VV12

Terms and conditions vacations from srdlk's vacation without a prescription prescription

dosage form

capsules

Possible product names

Linex Forte capsules 14 pcs

Laboratory Unit, Switzerland

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