Klenzit gel 15g

Release form, composition and packaging

Gel for external use, white, homogeneous.

1 g

adapalene 1 mg

disodium edetate, carbomer 940 (carbopol 940), propylene glycol, methyl parahydroxybenzoate, phenoxyethanol, poloxamer 407, sodium hydroxide, purified water.

15 g - lacquered aluminum tubes (1) - cardboard packs.

30 g - lacquered aluminum tubes (1) - cardboard packs.

pharmachologic effect

Adapalene is a retinoid metabolite, has comedolytic and anti-inflammatory activity, normalizes the processes of keratinization and epidermal differentiation.

The mechanism of action of adapalene is based on interaction with specific gamma receptors of epidermal skin cells.

As a result of the action of adapalene, in particular, there is a decrease in the cohesion" of epithelial cells at the mouth of the sebaceous hair follicle and a decrease in the prerequisites for the formation of microcomedones.

Adapalene has an anti-inflammatory effect in vitro and in vivo, acting on inflammatory factors by inhibiting the migration of leukocytes in the focus of inflammation and the metabolism of arachidonic acid.

Pharmacokinetics

The absorption of adapalene through the skin is very low (about 4% of the applied dose).

Excretion from the body occurs mainly with bile.

Indications for use

- acne.

Contraindications for use

Hypersensitivity to the components of the drug, pregnancy, lactation.

Dosage regimen

Outwardly.

Before using Klenzit gel, you need to cleanse and dry your face.

With a light touch, evenly apply the gel to the affected surface 1 time a day before going to bed on clean, dry skin, avoiding contact with the eyes and lips.

The therapeutic effect develops after 4-8 weeks of treatment, persistent improvement occurs after 3 months of treatment.

In some cases, due to short-term skin irritation, treatment may be suspended until the irritation disappears.

A second course of treatment is possible after consulting a doctor.

Overdose

Overdose is unlikely.

Side effect

Skin irritation (treatment must be suspended until skin irritation disappears or the frequency of use must be reduced).

Drug interactions

Since adapalene does not interact with oxygen and is not destroyed by light, it is possible to simultaneously treat acne with drugs such as clindamycin phosphate or benzoyl peroxide.

Application during pregnancy and lactation

It is not recommended to use the drug during pregnancy and breastfeeding.

special instructions

Avoid contact with eyes and lips.

In case of accidental contact of the drug on the mucous eyes, mouth or nose, rinse thoroughly with warm water.

Avoid direct sunlight.

skin irritation may appear.

Treatment can be continued if sun exposure is minimized (use of sunglasses and hats).

The simultaneous use of cosmetics with drying and irritating effect on the skin (for example, perfumes or alcohol-containing products) is not recommended.

Adapalene applied to the skin in the evening can be combined with acne medications applied in the morning.

Name ENG

CLENZIT

Clinical and pharmacological group

A drug for the treatment of acne.

Retinoid

ATX code

Adapalene

Dosage

0.1% x 15g

Structure

adapalen

Indications

Acne.

Storage conditions and periods

In a dark place at a temperature not exceeding 25 degrees.

(do not freeze).

Expiration date: 3 years

INN / Active ingredient

adapalen

Contraindications

Hypersensitivity to one of the ingredients of the drug, pregnancy, lactation.

Carefully:

Dermatitis, eczema.

Specifications

Category

Acne

Scope of the drug

General

Release form

Gel

Manufacturer country

India

Package quantity, pcs

one

Scope of application

Dermatology

Way of introduction

Outwardly

Vacation conditions

Without recipe

Brand name

Glenmark Pharma

,

Glenmark

The amount of the dosage form in the primary package

15 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Acne rash treatment

Anatomical and therapeutic characteristics

D10AD03 Adapalen

Dosage form

Gel for external use

Item weight, g

15

Dosage (volume) of the substance in the preparation

In 1 g: adapalene 1 mg

Expiration date in days

1095

Package weight, g

25

Mode of application

:

Outwardly.

Before using Klenzit gel, you need to cleanse and dry your face.

With a light touch, evenly apply the gel to the affected surface 1 time a day before going to bed on clean, dry skin, avoiding contact with the eyes and lips.

The therapeutic effect develops after 4-8 weeks of treatment, persistent improvement occurs after 3 months of treatment.

In some cases, due to short-term skin irritation, treatment may be suspended until the irritation disappears.

A second course of treatment is possible after consulting a doctor.

Information on technical characteristics, delivery set, country of manufacture "