Ketonal cream d / nar. approx. 5% tube 30g
Dosage:
5% x 30g
5% x 50g
Release form:
Gel
Cream
Scope of the drug
General
Release form
Cream
Manufacturer country
Germany
Package quantity, pcs
one
Way of introduction
Outwardly
Release form, composition and packaging
?
Cream for external use 5% white or almost white, homogeneous.
1 g
ketoprofen 50 mg
methyl parahydroxybenzoate - 2 mg, propyl parahydroxybenzoate - 0.5 mg, propylene glycol - 70 mg, isopropyl myristate - 50 mg, white petrolatum - 320 mg, elfakos ST9 - 30 mg, propylene glycol glyceryl oleate - 90 mg, magnesium sulfate - 5 mg. 5 mg, purified water - 382 mg ...
30 g - aluminum tubes (1) - cardboard packs.
50 g - aluminum tubes (1) - cardboard packs.
100 g - aluminum tubes (1) - cardboard packs.
pharmachologic effect
NSAIDs.
It has an analgesic, anti-inflammatory and anti-edema effect.
Inhibits the activity of COX, which leads to inhibition of the synthesis of prostaglandins.
In addition, ketoprofen inhibits lipoxygenase, bradykinin synthesis, stabilizes lysosomal membranes and prevents the release of enzymes involved in the inflammatory process.
Ketoprofen does not adversely affect the condition of the articular cartilage.
Pharmacokinetics
Absorption Ketoprofen is absorbed very slowly and practically does not accumulate in the body.
Bioavailability is 5%.
Ketoprofen penetrates into the subcutaneous tissue, ligaments and muscles, synovial fluid and reaches therapeutic concentrations there.
The concentration of the drug in blood plasma is extremely low.
Metabolism and excretion Ketoprofen is metabolized in the liver to form conjugates, which are mainly excreted in the urine.
Ketoprofen is characterized by slow urinary excretion.
Pharmacokinetics in special clinical situations Ketoprofen metabolism does not depend on age, the presence of severe renal failure or liver cirrhosis.
Indications for use
Symptomatic therapy of painful and inflammatory processes of various origins, including: - rheumatoid arthritis and periarthritis
- ankylosing spondylitis (ankylosing spondylitis)
- psoriatic arthritis
- reactive arthritis (Reiter's syndrome)
- osteoarthritis of various localization
- tendinitis, bursitis
- myalgia
- neuralgia
- sciatica
- Injuries of the musculoskeletal system (including sports), bruises of muscles and ligaments, sprains, ruptures of ligaments and muscle tendons.
Contraindications for use
- hypersensitivity to drug components
- hypersensitivity to salicylates, tiaprofenic acid or other NSAIDs, fenofibrate, UV blockers, fragrances
- violation of the integrity of the skin (eczema, weeping dermatitis, open or infected wound)
- a history of indications of bronchial asthma attacks caused by taking NSAIDs and salicylates
- a history of photosensitivity reactions
- exposure to sunlight, incl.
indirect sunlight and UV irradiation in a solarium throughout the entire treatment period and for another 2 weeks after stopping treatment
- III trimester of pregnancy
- children under 15 years of age.
With care: impaired liver and / or kidney function, erosive and ulcerative lesions of the gastrointestinal tract, blood diseases, bronchial asthma, chronic heart failure.
Dosage regimen
For external use.
A small amount of cream (about 3-5 cm) is applied with a thin layer on the skin over the lesion with light rubbing movements.
The cream is applied 2-3 times / day.
The duration of treatment without consulting a doctor should not exceed 14 days.
Overdose
Symptoms: irritation, erythema, itching.
Treatment: the drug should be discontinued.
The patient needs to see a doctor.
Side effect
Local reactions are the most common.
Determination of the frequency of adverse reactions: very often (? 1/10), often (? 1/100 and < 1/10), infrequently (? 1/1000 and < 1/100), rarely (? 1/10 000 and < 1 / 1000), very rarely (< 10,000).
Allergic reactions: very rarely - angioedema, anaphylaxis.
On the part of the skin and skin appendages: infrequently - erythema, itching, burning, eczema, t
Name ENG
KETONAL
Clinical and pharmacological group
NSAIDs for external use
ATX code
Ketoprofen
Dosage
5% x 30g
Structure
1 g of cream for external use contains: Active substance: ketoprofen - 50 mg
Excipients: methyl parahydroxybenzoate, propyl parahydroxybenzoate, propylene glycol, isopropyl myristate, petrolatum (white), elfakos ST9, propylene glycol glyceryl oleate, magnesium sulfate, water
Indications
Symptomatic therapy of painful and inflammatory processes of various origins, including:
rheumatoid arthritis and periarthritis
ankylosing spondylitis (ankylosing spondylitis)
psoriatic arthritis
reactive arthritis (Reiter's syndrome)
osteoarthritis of various localization
tendinitis, bursitis
myalgia
neuralgia
radiculitis
injuries of the musculoskeletal system (including sports), bruises of muscles and ligaments, sprains, ruptures of ligaments and muscle tendons.
INN / Active ingredient
ketoprofen
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 5 years
Contraindications
hypersensitivity to drug components
hypersensitivity to salicylates, tiaprofenic acid or other NSAIDs, fenofibrate, UV blockers, fragrances
violation of the integrity of the skin (eczema, weeping dermatitis, open or infected wound)
a history of indications of bronchial asthma attacks caused by taking NSAIDs and salicylates
a history of photosensitivity reactions
exposure to sunlight, incl.
indirect sunlight and UV irradiation in a solarium throughout the entire treatment period and for another 2 weeks after stopping treatment
III trimester of pregnancy
children under 15 years of age.
With care: impaired liver and / or kidney function, erosive and ulcerative lesions of the gastrointestinal tract, blood diseases, bronchial asthma, chronic heart failure.
Specifications
Scope of the drug
General
Release form
Cream
Manufacturer country
Germany
Package quantity, pcs
one
Way of introduction
Outwardly
Vacation conditions
Without recipe
Brand name
Sandoz
The amount of the dosage form in the primary package
30 g
Primary packaging type
Tuba
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
NSAIDs
Anatomical and therapeutic characteristics
M02AA10 Ketoprofen
Dosage form
Cream for external use
Dosage (volume) of the substance in the preparation
In 1 g: ketoprofen 50 mg
The target audience
Children
Expiration date in days
1826
Package weight, g
45
Category
:
Bruises, sprains
,
Joints
,
Treatment of diseases of the musculoskeletal system
,
Synovial fluid
,
Bone metabolism
Mode of application
:
For external use. < br> < br> Apply a small amount of cream (3-5 cm) with light rubbing movements in a thin layer on the skin of an inflamed or painful area of the body 2-3 times a day. < br> < br> The duration of the course of treatment should not exceed 14 days.
Drug action
:
Pain reliever
,
Anti-inflammatory
,
Analgesic
,
Decongestant
Information on technical characteristics, delivery set, country of manufacture