Iversect injection 50ml
DESCRIPTION
Iversect is a drug for the treatment and prevention of arachno-entomoses and nematodes of ruminants. Dosage form: injection solution.
COMPOSITION
The drug as an active ingredient contains ivermectin - 1%, as well as auxiliary components: benzyl alcohol - 5%, polyethylene oxide 400 - 50%, water for injection - 6.25%, novocaine - 1% and ethyl alcohol - up to 100%.
PHARMACOLOGICAL PROPERTIES
Iversect is a systemic antiparasitic drug from the class of macrocyclic lactones.
Ivermectin, which is part of the drug, is a mixture of hydrogenated avermectins B1a and B1b, has a wide spectrum of antiparasitic action, is active against larval and mature phases of development of nematodes of the gastrointestinal tract and lungs, hypodermic, nasopharyngeal, gastric gadfly, lice, bloodsuckers and sarcoptic mites. The mechanism of action of ivermectin lies in its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chlorine channels and gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite.
After parenteral administration of the drug, ivermectin is rapidly absorbed from the injection site and is distributed in the organs and tissues of the animal, providing a long-term parasiticidal effect. It is excreted from the body with urine and bile, in lactating animals - partly with milk.
According to the degree of exposure to the body, according to GOST 12.1.007-76, it belongs to moderately hazardous substances (hazard class 3), the active substance, ivermectin, belongs to extremely hazardous substances (hazard class 1).
In recommended doses, the drug has no embryotoxic, teratogenic and mutagenic effects; in the external environment is rapidly destroyed.
INDICATIONS
Iversect is prescribed to ruminants and pigs with a therapeutic and prophylactic purpose for nematodes, gadfly invasions and arachno-entomoses:
Cattle, sheep, goats and deer - at diktikauleze, ostergioze, gemonhoze, trihostrongileze, kooperioze, ezofagostomoze, nematodiroze, nematodirelleze, bunostomoze, strongyloidiasis, trihotsefaleze, elafostrongileze, thelaziasis, setarioze, onchocerciasis, hypodermosis, edemagenoze, tsefenomioze, Estrozi, sifunkulyatozah , psoroptosis, sarcoptic mange and chorioptosis.
Pigs - with ascariasis, esophagostomosis, trichocephalosis, strongyloidosis, metastrongylosis, hematopinosis and arcoptic mange.
APPLICATION
Kind of animal Dosage and method of administration
Cattle, sheep, goats and deer injected subcutaneously or intramuscularly at 0.2 mg of ivermectinan 1 kg of animal weight
Pigs injected subcutaneously or intramuscularly, 1 ml per 33 kg of animal weight (0.3 mg of ivermectin per 1 kg of weight)
If the volume of the injected solution is more than 10 ml, it should be administered to the animal in several places.
The drug is used in animals with nematodes and gadfly invasions once, with arachno-entomoses - twice with an interval of 8-10 days.
Treatment of animals with nematodes is carried out in the fall before stalling and in the spring before being taken to pasture, against gadfly infestations - immediately after the end of the summer of gadflies, against pathogens of arachno-entomoses - according to indications.
In case of mass processing of animals, each batch of the drug is preliminarily tested on a small group (5-7 heads) of animals. In the absence of complications, the entire livestock is processed within 3 days.
Manure from animals for the first two weeks after treatment with Iversect should be placed in manure accumulators or manure storages, excluding its entry into water bodies and groundwater.
In case of non-observance of the established period of repeated treatment of animals with arachno-entomoses, the use of the drug should be resumed as soon as possible in the same dosage.
SPECIAL INSTRUCTIONS
An unused preparation with an expired shelf life is neutralized with a 5% solution of caustic alkali or an aqueous suspension of slaked (or bleach) lime (1: 3) and disposed of in specially designated places, away from sources of drinking water and reservoirs.
It is forbidden to use empty vials from the medicinal product for household purposes. Areas of workplaces and transport contaminated with the drug are neutralized with 5% sodium hydroxide solution.
CONTRAINDICATIONS
It is not allowed to use Iversect in milking, sick with infectious diseases and malnourished animals, pregnant females whose milk will be used for food purposes, less than 28 days before lactation, as well as animals with increased individual sensitivity to ivermectins.
Iversect should not be used concurrently with avermectin-containing drugs, as well as mixed with other drugs in the same syringe.
OVERDOSE
With a significant overdose of Iversect, an animal may experience: swelling at the injection site, impaired coordination of movements, increased salivation, recumbency. There are no specific means of detoxification, general measures are used to remove the drug from the body.
SIDE EFFECTS
The peculiarities of the action of the drug during its first use were not revealed.
As a rule, side effects and complications when using Iversect in accordance with this instruction are not observed. With increased individual sensitivity of the animal to the components of the drug and the appearance of signs of intoxication, the treatment is stopped.
Slaughter of animals for meat is allowed no earlier than 28 days after the last injection of the drug. In the event of the forced slaughter of animals before the established deadline, the meat can be used as feed for fur animals.
PRECAUTIONS
When carrying out therapeutic and prophylactic measures using Iversect, the general rules of personal hygiene and safety measures provided for when working with medicines should be observed.
FIRST AID MEASURES
In case of accidental contact of the drug on the skin, it must be immediately washed off with soap and water if it gets into the eyes - rinse them for several minutes with running water, if it gets into the stomach - give a few glasses of warm water to drink. If necessary, seek help from a medical institution, having a container label or instructions for use of the drug with you.
SHELF LIFE AND STORAGE
Store in closed manufacturer's packaging in a dry place protected from direct sunlight, separate from food and feed, at temperatures from 0 В° C to 30 В° C. The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture, after opening the bottle - no more than 24 days.
PACKAGING
The drug is produced in glass bottles of 50 ml.
Specifications
Product subcategory
Injection
KolVUP
56
Manufacturer
Pharmbiomedservice
Teaser
drug for the treatment and prevention of arachno-entomoses and nematodes of ruminants