iron III hydroxide polymaltozat | Ferrum Lek syrup 50 mg / 5 ml, 100 ml

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SKU
BID462638
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Latin name

Ferrum Lek
Latin name

Ferrum Lek

Packaging

100 ml in dark glass bottles, complete with a dosage spoon, in a cardboard box.

Pharmacological action

Antianemic drug.

In the Ferrum Lek® preparation, iron is in the form of a complex compound of iron (III) hydroxide polymaltose.

The molecular weight of the complex is so great (about 50 kDa) that its diffusion through the gastrointestinal mucosa is 40 times slower than diffusion of ferrous iron. The complex is stable and does not release iron ions under physiological conditions. The iron of the multinuclear active zones of the complex is bound into a structure similar to that of the natural compound of iron, ferritin. Due to this similarity, the iron of this complex is absorbed only by active absorption. Iron-binding proteins located on the surface of the intestinal epithelium absorb iron (III) from the complex through competitive ligand exchange. Absorbed iron is mainly deposited in the liver, where it binds to ferritin. Later in the bone marrow, it is included in hemoglobin. The iron (III) complex hydroxide polymaltosate does not have the prooxidant properties inherent in iron (II) salts.

Indications

treatment of latent iron deficiency

treatment of iron deficiency anemia

prevention of iron deficiency during pregnancy.

Contraindications

excess iron in the body (e.g. hemochromatosis)

impaired iron utilization (e.g. anemia caused by lead intoxication, siderohrestical anemia)

anemia not associated with iron deficiency (e.g. hemolytic anemia, megaloban deficiency, megaloban )

hypersensitivity to the components of the drug.

Use in children

Use is possible according to indications and in doses taking into account the age of the patient. For children under 12 years of age, in connection with the need to prescribe the drug in low doses, it is preferable to use in the form of a syrup.

Use during pregnancy and lactation

In controlled trials with the use of the drug in the II and III trimesters of pregnancy, there was no negative effect on the mother or fetus. There were no harmful effects on the fetus when using the drug in the first trimester of pregnancy.

Dosage and administration

The drug is recommended to be taken during or immediately after a meal. Chewable tablets can be chewed or swallowed whole. The daily dose can be divided into several doses or taken 1 time.

Doses and duration of treatment depend on the degree of iron deficiency.

Syrup can be mixed with fruit or vegetable juices or added to baby food. The measuring spoon included in the package is used to accurately dispense the syrup.

With iron deficiency anemia, the duration of treatment is about 3-5 months. After normalizing the hemoglobin level, you should continue taking the drug for a few more weeks to replenish iron stores in the body.

Children under the age of 1 year are prescribed 2.5-5 ml (1/2-1 scoop) of syrup / day.

For children aged 1 to 12 years - 5-10 ml (1-2 measured spoons) of syrup / day.

Children over 12 years old, adults and mothers who are breast-feeding a baby - 1-3 tab. chewing or 10-30 ml (2-6 measured spoons) of syrup / day.

Pregnant women are prescribed 2-3 tablets. chewing or 20-30 ml (4-6 measured spoons) of syrup to normalize hemoglobin levels. After this, you should continue to take 1 tab. chewing or 10 ml (2 scoops) of syrup / day, at least until the end of pregnancy to replenish iron stores in the body.

With latent iron deficiency, the duration of treatment is about 1-2 months.

For children aged 1 to 12 years - 2.5-5 ml (1 / 2-1 measured spoon) of syrup / day.

Children over 12 years old, adults and mothers who are breast-feeding a baby - 1 tab. chewing or 5-10 ml (1-2 measured spoons) of syrup / day.

Pregnant women are prescribed 1 tab. chewing or 5-10 ml (1-2 measured spoons) of syrup / day.

Daily doses of Ferrum Lek® for the prevention and treatment of iron deficiency in the body.

Age Iron deficiency anemia Latent iron deficiency Prevention of iron deficiency

Children under 1 year2. 5-5 ml syrup (25-50 mg of iron) **

Children (1-12 years) 5-10 ml (50-100 mg of iron) 2.5-5 ml (25-50 mg of iron) *

Children (> 12 years), adults and nursing mothers 1-3 tab. chewing or 10-30 ml of syrup (100-300 mg of iron) 1 tab. chewing or 5-10 ml of syrup (50-100 mg of iron) *

Pregnant 2-3 tablets. chewing or 20-30 ml of syrup (200-300 mg of iron) 1 tab. chewing or 10 ml of syrup (100 mg of iron) 1 tab. chewing or 5-10 ml of syrup (50-100 mg of iron)

* - due to the fact that low doses of iron are necessary for this group of patients, it is not recommended in these cases to prescribe the drug in the form of tablets or syrup.

Side effects

From the digestive system: very rarely - a feeling of heaviness, a feeling of overflow and pressure in the epigastrium, nausea, constipation, diarrhea. When taking the drug, staining of feces in a dark color is noted, which is due to the removal of non-absorbed iron and does not have clinical significance.

Reported side effects were mostly mild and transient.

Drug Interaction

No interaction with other medicines or foods has been noted.

overdose

In cases of overdose with Ferrum Lek®, no signs of intoxication or signs of excess iron intake have been reported so far, since iron from the active substance is not present in the gastrointestinal tract in free form and does not suction.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 РC.

Expiration

3 years.

Deystvuyuschee substances

iron III hydroxide polymaltozat

Pharmacy terms

Prescription

Sandoz, Switzerland

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