Iodopiron solution for external use 1%, 100 ml

Disinfection of the surgeon's hands, operating field, surgical gloves and elbow bends, donors, burns, purulent and infected wounds, osteomyelitis.

Outwardly, 0.1-0.5% aqueous solutions are prepared from a 1% solution immediately before use. As an antiseptic for treating the hands of the surgeon, 0.1% (based on active iodine) solutions (5 ml) are used, the operating field is wiped with a napkin soaked in the solution. With extensive burns, the patient is immersed in a bath with a solution of 1:32 or 1:50 for 10-15 minutes. For the complex treatment of purulent and infected wounds, osteomyelitis, disinfection of surgical gloves and treatment of the elbow bends of donors, 0.5% and 1% (based on active iodine) solutions of Iodopiron are used.

1000 ml of solution contains:
Active ingredient: Iodine - 14.10 g
Excipients: Potassium iodide - 13.80 g; povidone K-17 - 122.10 g; purified water up to 1000 ml.

Hypersensitivity to the drug's components, hyperthyroidism, Duhring's dermatitis herpetiformis, thyroid adenoma, renal failure, before radioactive iodine therapy; neonatal period (especially in premature babies).

Carefully

Childhood, pregnancy, breastfeeding period.

Trade name:

Yodopiron

INN or grouping name:

Povidone-Iodine + [Potassium Iodide]

Dosage form:

Solution for external use

Composition:

1000 ml of solution contains:
Active ingredient: Iodine - 14.10 g
Excipients: Potassium iodide - 13.80 g; povidone K-17 - 122.10 g; purified water up to 1000 ml.

Description

A film-forming dark brown liquid, odorless or with a weak characteristic odor.

Pharmacotherapeutic group

Antiseptic.

Pharmacological properties

Iodine in the form of a complex of polyvinylpyrrolidone iodine. The concentration of active iodine is not less than 1%. An antiseptic agent, when applied externally, has a bactericidal (against a wide range of gram-positive and gram-negative microorganisms, including antibiotic-resistant strains of Escherichia coli, Staphilococcus aureus and Proteus), antifungal effect.

Indications for use

• Disinfection of the surgeon's hands, operating field, surgical gloves and elbow bends, donors;

• burns,

• purulent and infected wounds,

• osteomyelitis.

Contraindications

• Hypersensitivity to the components of the drug,

• hyperthyroidism,

• Duhring's dermatitis herpetiformis,

• adenoma of the thyroid gland,

• renal failure

• before radioactive iodine therapy,

• neonatal period (especially in premature babies).

Carefully

Childhood, pregnancy, breastfeeding period.

Application during pregnancy and during breastfeeding

It is not recommended to use the drug during pregnancy and during breastfeeding (if necessary, use is possible under individual medical supervision).

Method of administration and dosage

Outwardly, 0.1-0.5% aqueous solutions are prepared from a 1% solution immediately before use. As an antiseptic for treating the hands of the surgeon, 0.1% (based on active iodine) solutions (5 ml) are used, the operating field is wiped with a napkin soaked in the solution. With extensive burns, the patient is immersed in a bath with a solution of 1:32 or 1:50 for 10-15 minutes. For the complex treatment of purulent and infected wounds, osteomyelitis, disinfection of surgical gloves and treatment of the elbow bends of donors, 0.5% and 1% (based on active iodine) solutions of Iodopiron are used.

Side effect

Dry skin, allergic reactions (pruritus, hyperemia at the application sites, urticaria). When applied to a large wound surface, a fast-passing burning sensation is possible.

Overdose

Symptoms: irritation at the site of application.
Treatment: symptomatic.
Prolonged use (more than 7-10 days) can cause the phenomenon of iodism ('metallic' taste in the mouth, increased salivation, swelling of the eyes or larynx, etc.), in the event of which you should stop using the drug and consult a doctor. If iodine is accidentally swallowed, the mucous membrane of the gastrointestinal tract may be damaged. The stomach should be flushed with 0.5% sodium thiosulfate solution, activated charcoal, starch paste, flour broth, mucous drink, milk and / or intravenously every 4 hours with 10 ml of 10% sodium thiosulfate solution are used as an antidote, as well as symptomatic therapy.

Interaction with other medicinal products

Pharmaceutically incompatible with disinfectants containing mercury, oxidants, alkali salts and acidic substances, with medicines for external use containing enzymes (iodine reduces the activity of enzymes). In the presence of blood, the bactericidal effect may be reduced. With simultaneous use with lithium preparations, a synergistic hypothyroid effect is possible.

special instructions

Avoid contact with eyes.
Do not heat before use.
Do not use on insect bites, pets and wild animals.
During use, test papers for detecting occult bleeding in stool and urine may show false positive results due to the strong oxidative effect of povidone iodine.
Coloring on skin and fabrics can be easily washed off with water.

Influence on the ability to drive vehicles, mechanisms

Does not affect the ability to drive a vehicle and engage in other potentially hazardous activities that require increased concentration.

Release form

Solution for external use.
10, 15, 20, 25, 30, 40, 50, 100 ml in polyethylene bottles or in orange glass bottles. Each bottle, along with instructions for medical use, is placed in a cardboard box.
50, 100, 150, 200, 300 vials of 10, 15, 20, 25, 30 ml; 30, 50, 80, 100, 120, 150 vials of 40, 50 ml; 30, 50, 80, 100 100 ml vials, together with an equal number of instructions for use, are placed in a cardboard box ('for hospitals').
100, 200, 300, 400, 500, 1000 ml in glass bottles or bottles made of polyethylene terephthalate ('for hospitals').
On 3, 5, 10 liters of the drug in polyethylene canisters ('for hospitals').
20, 30, 50, 60, 80, 100 bottles, 100 ml vials; 10, 20, 30, 50 bottles, 200 ml vials; 10, 15, 30 bottles, vials of 300 ml; 10, 15, 20 bottles, 400 ml vials; 6, 12, 18 bottles, 500 ml vials; 6, 8, 9, 10 bottles, vials of 1000 ml, together with an equal number of instructions for use, are placed in a cardboard box ('for hospitals').

Storage conditions

In a dark place at a temperature not exceeding 25 ? C.
Keep out of the reach of children.

Shelf life

2 years. Do not use after the expiration date printed on the package.

Vacation conditions

Available without a prescription.