Inspector Kvadro K drops for cats 4-8kg 0.8ml

DESCRIPTION

Inspector Qu.adro K is a drug for the treatment and prevention of entomosis, otodectosis, notoedrosis, acarosis in cats. In appearance, it is a transparent oily liquid from colorless to yellow.

COMPOSITION

Inspector Quadro K in 1 ml contains as active ingredients: fipronil -107 mg, praziquantel -42.8 mg, pyriproxyfen -21.4 mg and moxidectin -10.7 mg, as well as auxiliary substances: diethylene glycol monoethyl ether (DEME), N-methylpyrrolidone, butylhydroxyanisole, butylhydroxytoluene.

PHARMACOLOGICAL PROPERTIES

Inspector Kvadro K belongs to the pharmacotherapeutic group of antiparasitic agents in combinations.

The active ingredients included in the preparation provide a wide range of antiparasitic action against sarcoptoid ticks (Notoedres cati, Otodectes cynotis), fleas (Ctenocephalides felis), lice (Felicola subrostratus) and ixodid ticks (Dermacentice spp., Rpp. Spp. , as well as larval and sexually mature phases of development of nematodes (Toxocara mistax, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum), cestodes (Dipylidium caninum, Alveococus multilocularis, Taenia spp., Mesocestoides lineatus microfilaria, Diphyllobilar phases) and Dirofilaria repens, which are parasitic in cats.

Fipronil is an insectoacaricide of the phenylpyrazole group, its mechanism of action is to block the gamma-dependent receptors of arthropods, disrupt the transmission of nerve impulses and the activity of the nervous system, which leads to paralysis and death of ectoparasites.

Praziquantel is a compound of the pyrazinisoquinoline group, has a pronounced effect against sexually mature and immature cestodes; the mechanism of its action is based on inducing the breakdown of tegument and inhibition of fumarate reductase, persistent depolarization of muscle cells of the helminth, disruption of energy metabolism, which causes paralysis and death of cestodes and promotes their excretion from the gastrointestinal tract.

Moxidectin is a semisynthetic compound of the milbemycin group (macrocyclic lactones), which stimulates the release of gamma-aminobutyric acid and binds to postsynaptic receptors, causing disruption of muscle innervation, paralysis and death of ectoparasites and nematodes.

Pyriproxyfen, disrupting the hormonal balance of arthropods, causes developmental abnormalities and sterilization of adults. The mechanism of action of pyriproxyfen consists in disrupting the processes of chitin synthesis and molting of larvae, prevents the development of full-fledged pupae and causes the death of insects in the preimaginal phases of development, which leads to the termination of the replacement of the population of ectoparasites.

After cutaneous application, fipronil and pyriproxifen, which are part of the Inspector Quadro K preparation, quickly spread over the surface of the epidermis and have a contact insectoacaricidal effect, preventing insect and tick infestation. Moxidectin and praziquantel enter the systemic circulation, are distributed in organs and tissues and have a systemic antiparasitic effect on intestinal nematodes, cestodes, larvae of dirofilariae migrating in the bloodstream, as well as sarcoptoid, demodectic and ixodid ticks. Insectoacaricidal and anthelmintic effect of the drug after a single treatment lasts 4-6 weeks.

Inspector Kvadro K, according to the degree of impact on the body, belongs to moderately hazardous substances (hazard class 3 in accordance with GOST 12.1.007-76), in recommended doses it does not have a local irritant, resorptive-toxic and sensitizing effect. The drug is toxic to rabbits, bees, fish and other aquatic organisms.

DOSAGE AND APPLICATION

Inspector Kvadro K is prescribed to cats for the treatment and prevention of entomoses, otodectosis, notoedrosis, acarosis caused by ixodid ticks, nematodes of the gastrointestinal tract (toxocariasis, toxascariasis, uncinariosis, ankylostomiasis, cestodioses, dyestocytosis), cestodiasis (teniidiosis) also for the prevention of dirofilariasis.

Inspector Quadro K is applied to animals by application to dry, intact skin, in the doses indicated in the table:

Animal weight, kg Drug dose (nominal pipette volume), ml

from 1 to 4 kg 0.4 ml

from 4 to 8 kg 0.8 ml

from 8 to 15 kg 1.5 ml

When treating cats weighing more than 15 kg, the drug is used at the rate of O, 1 ml per kilogram of animal weight, using a combination of pipettes or tubes of various packaging, when treating cats weighing less than 1 kg - at the rate of one drop of solution (0.05 ml) per 0 , 5 kg of animal weight.

To destroy fleas, lice and ixodid ticks, the drug is applied by drop ('spot-on') to the skin in places inaccessible for licking - between the shoulder blades at the base of the neck. Treatment of animals for therapeutic purposes is carried out once, to prevent re-invasion - once every 4-6 weeks throughout the season of ectoparasite activity.

In order to prevent re-infestation by fleas, animals are replaced by bedding or treated with an approved insecticidal agent in accordance with the instructions for use.

The acaricidal effect of the drug manifests itself after 12 - 24 hours, taking into account this, the treatments should be carried out no later than 24 hours before the intended walking of the animal in the places of possible habitation of ixodid ticks (parks, squares, forests).

To destroy the sucked ixodid ticks on the body of the animal, Inspector Quadro K in the amount of 1 drop is applied to the tick and the place of its attachment to the skin. If the tick does not spontaneously fall off within 20 minutes, it is carefully pulled out of the skin with tweezers and destroyed.

For the treatment of otodectosis, the external auditory canal is cleaned of scabs and crusts, then 3 drops of the drug are instilled into each ear (drops must be injected into both ears), the auricle is folded in half lengthwise and its base is massaged. The remainder of the drug in the pipette or tube used (based on the weight of the animal) is applied to the skin between the shoulder blades. Treatment is carried out 2 - 3 times with an interval of 7 - 1 O days. In case of complication of otitis media, antimicrobial and anti-inflammatory drugs are prescribed.

If necessary, the course of treatment is repeated after 1 month under the control of microscopy of scrapings.

In the case of perforation of the tympanic membrane, the drug is used by drip application to the skin between the shoulder blades at the base of the neck at the dose indicated in the table.

In case of notoedrosis, Inspector Quadro K is applied in a thin layer to the affected areas of the body previously cleaned of scabs with the capture of borderline healthy skin up to 1 cm2 at the rate of O, 1 ml per kg of weight. Processing is carried out 2 - 4 times with an interval of 7 - 1 O days. Animals with extensive lesions are treated in two doses with an interval of 1 day, applying the drug to the affected areas first of one and then the other half of the body. Treatment is recommended to be carried out in a complex manner with the use of pathogenetic and symptomatic drugs until the animal's clinical recovery, which is confirmed by two negative results of microscopic examinations of scrapings.

To prevent licking of the drug, the animal is put on a muzzle, a neck collar, or the jaws are closed with a loop of tape, which are removed 20 minutes after applying the drug.

For deworming, Inspector Kvadro K is applied by applying to the skin in the doses indicated in the table, for therapeutic purposes once, for prophylactic purposes - once a month.

In order to prevent dirofilariasis in regions unfavorable for the disease, the drug is used in the spring-summer-autumn period: before the beginning of summer mosquitoes and mosquitoes (carriers of the pathogen D. immitis) once, then once a month and the last time in the season 1 month after the end of the flight insects.

CONTRAINDICATIONS

Contraindication to the use of Inspector Kvadro K is the individual hypersensitivity of the animal to the components of the drug. Auricular use of the drug (for ear scabies) is not allowed when the tympanic membrane is perforated. Patients with infectious diseases and weakened cats and animals of other species are not subject to treatment. Handling cats less than 1 kg should be done with caution under the supervision of a veterinarian.

Kittens under 7 weeks of age cannot be processed. Treatment of cats during pregnancy and feeding of offspring, if necessary, is carried out with caution under the supervision of a veterinarian.

SHELF LIFE AND STORAGE

The shelf life of the drug in the manufacturer's sealed packaging, subject to storage conditions, is 2 years from the date of production. Store the drug in a closed manufacturer's packaging, protected from direct sunlight, separate from food and feed, at a temperature from 0 В° C to 30 В° C and a relative humidity of no more than 60%.

PACKAGING

Inspector Kvadro K is produced packaged in 0.8 ml in polymer pipettes, individually packed in polymer blisters, placed in cardboard boxes along with instructions for use.

Specifications

Bonus points

0

Product subcategory

Drops from fleas and ticks

KolVUP

40

Manufacturer

Ecoprom

Temperature regime

from 0 to +30

Teaser

for the treatment and prevention of entomosis, otoectosis, notoedrosis, acarosis in cats