Hymekromon | Odeston tablets 200 mg, 50 pcs.

Release form

Tablets

Packing

50 pcs.

Pharmacological action

Cholagogue. Increases the formation and secretion of bile. It has a selective antispasmodic effect on the bile ducts and sphincter of Oddi. The drug does not reduce gastrointestinal motility and blood pressure.

Reduces stagnation of bile, prevents the crystallization of cholesterol and, thereby, the development of cholelithiasis.

Pharmacokinetics

Absorption and distribution of

After oral administration, it is rapidly absorbed from the digestive tract. Cmax in the blood after oral administration is achieved after 2-3 hours. It weakly binds to plasma proteins.

Excretion of

T1 / 2 is about 1 hour. Excreted in the urine: about 93% as glucuronate, 1.4% as sulfonate, 0.3% unchanged.

Indications

biliary dyskinesia and sphincter of Oddi for hyperkinetic type

non-calculous chronic cholecystitis, cholangitis, cholelithiasis

condition after surgery on the gall bladder and bile ducts, gout, yellowing, and appetite.

Contraindications

hypersensitivity

biliary obstruction

renal / hepatic insufficiency

ulcerative colitis, Crohn's disease

gastric ulcer and duodenal ulcer

hemophilia 18 years of age.

Use during pregnancy and lactation

There is no data on the safety of the use of gimecromon during pregnancy and lactation.

Prescribing Odeston during pregnancy and lactation (breastfeeding) is permissible only in cases where the intended benefits to the mother outweigh the potential risk to the fetus or child.

Special instructions

Special precautions for disposal of unused drug

Do not dispose of drugs in the sewer or in your household waste containers. You should contact your pharmacist about how to dispose of an unused product. These activities will help protect the environment.

Effect on the ability to drive vehicles and control mechanisms

The drug does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Composition

1 tab. contains:

Active substances: gimekromon 200 mg

Excipients: potato starch - 45 mg, gelatin - 3 mg, sodium lauryl sulfate - 1 mg, magnesium stearate - 1 mg.

Method approx Do not take a double dose of the drug in order to compensate for the missed.

Side effects of the

From the digestive system: diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa.

Other: allergic reactions, headache.

Drug interaction

With the simultaneous use of morphine, which causes spasm of the sphincter of Oddi, weakens the effect of Odeston.

With the simultaneous use of Odeston with metoclopramide, a mutual weakening of action is noted.

Odeston enhances the effects of indirect anticoagulants.

Overdose

There have been no reports of an overdose of Odeton at this time.

Storage Conditions

In a dark place at a temperature not exceeding 25 РC.

Shelf life

3 years.

Active ingredient

Gimekromon

Conditions for dispensing from pharmacies

Without a prescription

dosage form

tablets

Possible product names

ODESTON 0.2 N50 TABLE

Odeston 200mg Tab. X20

Odeston 200mg Tab. X50

Odeston 200mg tablet X50 Blist. (ACTION 10)

Odeston 200mg tab. X50 Blist. (ACTION)