Hydrolyzat human placenta | Laennec solution for iv. and w / mouse. enter ampoules 2 ml 10 pcs. pack

Special Price $244.72 Regular Price $275.00
In stock
SKU
BID480250
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Release form

Injection
Release form

Injection

Packing

10 ampoules of 2 ml.

Pharmacological action

Laennec - immunomodulating and hepatoprotective drug.

The drug exhibits immunomodulating properties due to its ability to stimulate humoral immunity and increase the functional activity of phagocytes and natural killers. Increases the bactericidal activity of peripheral blood leukocytes, manifested in their ability to destroy the captured pathogen. The cytokines that make up the drug activate the metabolic and supervisory functions of skin cells.

Biologically active substances contained in the hydrolyzate stimulate the regeneration (proliferation) of hepatocytes, exhibit detoxification properties, reduce the deposition of lipids and cholesterol in the liver cells, increase the activity of tissue respiration, activate the metabolism in the liver, reduce the intensity of the development of connective tissue in the liver.

Indications

chronic recurrent herpes (as part of complex therapy)

atopic dermatitis of moderate and severe severity, incl. complicated (as part of complex therapy)

chronic liver diseases: steatohepatitis (alcohol, metabolic and mixed etiology) - in the form of monotherapy.

Contraindications

childhood

pregnancy

lactation

hypersensitivity to the drug.

Caution should be used in patients with a polyvalent allergy to drugs, in the elderly.

Use during pregnancy and lactation

The drug is contraindicated in pregnancy and during breastfeeding.

Special instructions

According to current data, the drug can be prescribed for the elderly. However, given that the physiological functions of the elderly are deteriorating, the drug should be used under close supervision.

Pediatric use

No studies have been conducted on the safety of using Laennec in infants (including premature infants) and minors. Use in children is not recommended.

Composition of

1 ampoule contains:

Active ingredient:

human placenta hydrolyzate 112 mg

Excipients:

water for injection,

sodium hydroxide or hydrochloric acid (for pH adjustment).

Dosage and administration of

In chronic recurrent herpes and atopic dermatitis, the drug is administered intravenously: 10 ml (560 mg of the placental hydrolyzate) of the drug (5 ampoules) are dissolved in 250-500 ml of a 5% dextrose solution or physiological saline and injected through the ulnar vein for 1.5-2 hours. Injections are carried out 3 times a week with an interval of 2 days. The course of treatment is 10 injections.

In chronic liver diseases (steatohepatitis / alcohol, metabolic and mixed etiology /), the drug is administered in / m at 2 ml / day (112 mg of placental hydrolyzate). Depending on the severity of the disease, the frequency of injections can be increased up to 2-3 times (6 ml) / day. The drug can be administered intravenously: 10 ml (560 mg of placental hydrolyzate) of the drug (5 ampoules) are dissolved in 250-500 ml of 5% dextrose solution or physiological saline and injected through the ulnar vein for 1.5-2 hours. Injections are carried out 2 times in Week. The course of treatment is 2-3 weeks.

Side effects

Side effects are noted in 3.7% of patients.

Clinically significant adverse reactions: allergic reactions possible.

Other adverse events: pain at the injection site (2.56%), allergic reactions (redness, itching) (0.37%), numbness at the injection site (0.37%), gynecomastia (0.37%) - a causal relationship with the administration of the drug has not been established.

Drug interaction

When mixing a Laennec solution with other drugs that are strong bases (pH above 8.5), the activity of the drug decreases.

To date, no other clinically significant drug drug interactions have been identified.

Overdose

No cases of overdose with Laennek have been reported at this time.

Storage Conditions

The product should be stored in a dark place out of the reach of children at 18 ° to 25 РC.

Shelf life

3 years.

Deystvuyushtee substance

Gidrolizat platsent per person

Terms and conditions

prescription

dosage form

injection and infusions

Possible product names

Laennec rr for iv. and w / mouse. enter ampoules 2 ml 10 pcs.

Rana Clinic, Japan

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