Helmicide 100 tablets
DESCRIPTION
Helmicide tablets (Helmicid taYets) is a medicinal product for oral use for deworming cattle and small ruminants. In appearance, the drug is round, biconvex or flat tablets from white to gray, with a line on one side and a logo (a cross in the center of the shield) on the other.
COMPOSITION
The medicinal product as active ingredients in 1 tablet contains: albendazole-360 mg and oxyclosanide-175 mg, as well as auxiliary substances: polyvinylpyrrolidone, potato starch, calcium stearate and lactose.
PHARMACOLOGICAL PROPERTIES
Helmicide tablets belongs to the group of anthelmintic drugs.
The combination of albendazole and oxyclosanide, which are part of the drug, provides a wide range of anthelmintic action of tablets against nematodes, cestodes and trematodes.
Albendazole, a compound of the benzimidazole group, is effective in mono- and polyinvasions caused by imago and larvae of nematodes and cestodes, as well as imago of trematodes. Possessing an ovocidal effect, it reduces the infection of pastures with helminth eggs.
The mechanism of action of albendazole is to selectively suppress beta-tubulin polymerization, which leads to the destruction of cytoplasmic microtubules of cells of the intestinal tract of the helminth; changing the course of biochemical processes, albendazole inhibits glucose utilization and inhibits the synthesis of ATP, blocks the movement of secretory granules and other organelles in the muscle cells of helminths, causing their death.
Oxyclozanide is a compound of the salicylanilide group, has a pronounced trematodocidal effect on larval and mature phases of development of trematodes Fasciola spp., Paramphistomum spp. and Dicrocoelium lanceatum parasitizing ruminants.
The mechanism of action of oxyclozanide is to disrupt the phosphorylation processes in helminths, to reduce the activity of fumarate reductase and succinate dehydrogenase, which leads to paralysis and death of trematodes.
When administered orally, albendazole and oxyclosanide are rapidly absorbed in the gastrointestinal tract and penetrate into organs and tissues; from the body of animals are excreted mainly in the urine and partly with feces in unchanged form and in the form of metabolites.
Helmicide tablets, according to the degree of impact on the body, are classified as low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses they are well tolerated by animals.
PURPOSE
Helmicide tablets are used for deworming cattle and small ruminants for the following diseases: trematodosis (acute and chronic fascioliasis, dicroceliosis, paramphistomiasis); nematodes of the gastrointestinal tract (hemonchosis, bunostomosis, esophagostomosis, nematodyrosis, ostertagiosis, habertiosis, cooperiosis, strongyloidosis, trichostrongylosis, trichocephalosis, neoascariasis); nematodes of the lungs (dictyocaulosis, protostrongylidosis, mulleriosis, cystocaulosis); cestodoses (moniesiasis, avitellinosis, tizanesiosis).
DOSAGE AND APPLICATION
Helmicide tablets are administered to animals individually once orally (inside) in the following doses (number of tablets per animal weight): cattle with fascioliasis, dicroceliosis, paramphistomiasis and ostertagiasis -1 tablet per 3-5 kg; with cestodoses and nematodes (excluding ostertagiosis) -1 tablet per 50 kg; sheep and goats with fascioliasis, dicroceliosis, paramphistomiasis and protostrongylidosis -1 tablet per 45 kg; with cestodoses and nematodes (excluding protostrongylidoses) -1 tablet per 70 kg. A special diet and the use of laxatives before deworming are not required.
SPECIAL INSTRUCTIONS
When working with tablets, you should follow the general rules of personal hygiene and safety measures provided for working with medicines. In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they should be rinsed with plenty of water. People with hypersensitivity to the components of the drug should avoid direct contact with the tablets. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for use of the drug or a label with you). It is forbidden to use empty containers from under the medicinal product for household purposes, it must be disposed of with household waste.
Slaughter of animals for meat is allowed no earlier than 21 days after deworming. In case of forced slaughter of a previously established period, the meat can be used as feed for fur animals.
Milk of dairy animals must not be used for food purposes within 4 days after deworming. The milk obtained earlier than the established period can be used after boiling in animal feed.
CONTRAINDICATIONS
Contraindication to the use of tablets is the increased individual sensitivity of the animal to the components of the drug. The drug should not be used by patients with infectious diseases and malnourished animals.
It is forbidden to use the drug during the breeding period, pregnant sheep, goats and pregnant cows in the first half of pregnancy. The possibility of using the drug in lactating females and newborn animals is determined by the attending veterinarian based on an assessment of the ratio of benefits to the possible risk of its use.
SIDE EFFECTS
When using tablets in accordance with this instruction, side effects and complications, as a rule, are not observed. With increased individual sensitivity of the animal to the components of the drug, individual reactions are possible (depression, increased salivation, diarrhea), which spontaneously disappear within 2-4 hours and do not require the use of drugs.
SHELF LIFE AND STORAGE
The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of production. Do not use the drug after the expiration date. The tablets are stored in the manufacturer's sealed packaging, protected from direct sunlight, separately from food and feed, at a temperature from 0 0C to 25 В° C. The drug, packaged in bags, is stored under the specified conditions in a place protected from moisture.
PACKAGING
The drug is produced in packs of 100 tablets in polymer bags, individually placed in cardboard boxes. Each consumer package is supplied with instructions for use.
Specifications
Bonus points
0
KolVUP
40
Manufacturer
Agrovetzashita
Temperature regime
from 0 to +25
Teaser
for deworming cattle and sheep with trematodes, nematodes and cestodes